Ain Shams University

Frequency of pathological gambling among Egyptian patients with substance use disorders: a cross-sectional study

Abstract Background Pathological gambling and substance use disorders (SUDs) share overlapping neurobiological pathways and clinical features. However, the prevalence of pathological gambling among Egyptian patients receiving treatment for SUDs remains insufficiently explored. Ob...

Microcomputed tomographic evaluation of root filling removal techniques in long oval mandibular premolar canals

Abstract This investigation evaluated the efficiency of various root canal filling removal techniques in removing gutta-percha (GP) and iRoot SP sealer in mandibular premolars with long-oval shaped canal using micro-computed tomography (micro-CT). Forty-eight mandibular premolars...

BRCA1/2 variant profiling and HPV/HMTV DNA detection in a cohort of Egyptian women with breast cancer

Abstract Breast cancer (BC) is a multifactorial disease influenced by both genetic and environmental factors. Pathogenic variants in BRCA1 and BRCA2 significantly increase hereditary BC risk, while oncogenic viruses such as human Papillomavirus (HPV) and human mammary tumor virus...

Introducing the toroidal blade concept to small-scale horizontal axis wind turbine: A CFD study

This study evaluates the toroidal blade concept in horizontal-axis wind turbine design compared to conventional shapes. Both designs utilize the NACA 4412 airfoil, with the toroidal rotor featuring elliptical geometry. Three-dimensional transient CFD simulations using URANS equat...

Ensemble transformer-based framework for predicting finger angles

Abstract More than 50% of individuals with upper-limb amputation reject the use of prosthetic devices, primarily due to limitations in functionality, comfort, and intuitive control. Accurate estimation of finger joint angles is a key requirement for proportional prosthetic contro...

Hypobaric hypoxia at 3,466 m suppresses hepatic bile acid metabolism and remodels the tumor lipidome in mice

Abstract Background Systemic hypoxia induces whole-body metabolic adaptation, but its impact on tumor metabolism and hepatic bile acid (BA) pathways remains poorly defined. Methods We investigated how high-altitude (HA) hypobaric hypoxia at 3,466 m affects tumor growth, tumor lip...

Oncology nurse navigator core competencies and patient satisfaction

Oncology nurse navigators (ONNs) are increasingly recognized for their vital role in improving the quality of cancer care by supporting patients throughout their treatment journey. In Egypt, nurse navigation implementation remains limited, and empirical evidence examining the rel...

Bianchi IX dynamics with a phantom field

Abstract We consider Bianchi IX dynamics of a Universe filled with a massless phantom field. Such an exotic matter source enables regimes impossible in vacuum or with a standard scalar field. In particular, two Kasner indices of BKL oscillations can be simultaneously negative, an...

Colonoscopic and histopathological findings in obese patients with fibroscan-detected hepatic steatosis: a cross-sectional study

Abstract Background Obesity and steatosis are increasingly linked to systemic and gut inflammation, yet the frequency of colitis in this population remains insufficiently defined. This study aimed to characterize the frequency and spectrum of colonic inflammatory, endoscopic, and...

Harnessing shrimp shell waste: enhanced chitinase production through optimization techniques for ecofriendly solutions using bacteria

Chitinous wastes, particularly shrimp shell residues, represent a major underutilized biomass resource with significant potential for bioconversion into high-value products. In this study, four thermophilic bacterial strains ( Bacillus amyloliquefaciens BT 2022, Bacillus lichenif...

Single and multiple oral giant cell fibromas: a case report and review of the literature

Giant cell fibroma (GCF), a benign fibrous growth, accounts for about 4.7% of all oral benign or reactive fibrous growths. GCF commonly occurs in Caucasians, with a minor female predilection and a peak occurrence in the first three decades of life. Clinically, gingival nodules th...

Hippobosca equina as an emerging threat in northern temperate zones: Species distribution modelling under climate change

Climate change poses significant threats to arthropod vectors of veterinary importance. Hippobosca equina, the forest fly, is an obligate ectoparasite of ungulates with demonstrated capacity for pathogen transmission. We employed maximum entropy modelling to predict current and f...

How does rewetting propagate through restored peatlands? An integrated surface–subsurface modelling analysis of water–table dynamics

Abstract Peatland restoration, through drainage suppression, is widely implemented to recover hydrological and ecological functions; however, the groundwater system responses governing rewetting efficiency remain insufficiently quantified across spatiotemporal scales. Here, a bor...

Geomechanical stratigraphy defines foundation suitability of Turonian carbonates in New Giza Egypt

Geotechnical parameters—including uniaxial compressive strength (UCS), Young’s modulus (E), Poisson’s ratio (ν), and derived competence indices (Material Index γ, Concentration Index Ci, and Stress Ratio Si)—were evaluated to assess foundation quality in Turonian carbonate rocks...

Insecticidal activity of Metarhizium anisopliae-mediated nanoparticles and fungal metabolites against the red palm weevil, Rhynchophorus ferrugineus

Abstract This study evaluated the insecticidal activity of green-synthesized metallic nanoparticles (Ag, CuO, and ZnO) and the ethanolic extract of Metarhizium anisopliae against the red palm weevil ( Rhynchophorus ferrugineus ). Physicochemical characterization confirmed the suc...

Elastic intramedullary nails versus submuscular locked plates in treatment of pediatric length stable femoral shaft fractures: A prospective, randomized clinical trial

Objectives: Diaphyseal femoral fractures are frequently encountered in children aged 6–14 years and remain a management challenge. The optimal fixation strategy for length-stable fracture patterns in this age group remains debated, particularly regarding the relative benefits of...

Evaluation the role of quinoa seeds in attenuation the brain cellular senescence and aging induced by D-galactose and γ-radiation in rats: insights into autophagy, telomerase activity, amyloid-β and tau proteins

The gradual loss of cognitive function, manifested by impaired learning and spatial memory, is a hallmark of brain senescence during aging. However, effective natural interventions targeting multiple mechanisms involved in aging-related neurodegeneration remain limited. This stud...

Integrated geophysical and hydrogeochemical characterization of a fractured limestone aquifer in new Tuna El Gabel village, West El-Minia, Egypt

Abstract Groundwater is a vital component of water supply in arid regions, such as West El-Minia Governorate, Egypt, where water scarcity is projected to worsen, with per capita water supply expected to drop below 500 m 3 by 2025. In response, Egypt’s One and a Half Million Fedda...

Knowledge, attitudes, and practices (KAP) toward stroke prevention among hypertensive patients in Egypt: a multicenter cross-sectional study

Abstract Stroke is the second most common cause of death worldwide and represents a major health concern in Egypt. Hypertension is the most important modifiable risk factor for stroke; we aim to assess knowledge, attitudes, and practices (KAP) toward stroke prevention among hyper...

Association between fibroblast growth factor 23 and left ventricular hypertrophy in Egyptian patients on regular hemodialysis

Abstract Background Cardiovascular disease remains the leading cause of mortality in end-stage renal disease (ESRD) patients, with left ventricular hypertrophy (LVH) representing a prevalent and prognostically significant complication. Fibroblast growth factor 23 (FGF23), a bone-...