Academy of Scientific and Innovative Research

Insight into the sunlight-mediated photodegradation of active pharmaceuticals using ZnO-doped TiO2/Carbon nanocomposite derived from leather waste

Treatment of pharmaceutical wastewater is gaining importance due to health risks. In this study, carbon sourced from vegetable-tanned leather waste was utilized to develop an effective photocatalyst. ZnO incorporated TiO 2 /carbon nanocomposites were synthesized via the sol–gel r...

Role of Aromatic Topology in Hyper-Crosslinked Polymers on CO2 Adsorption and CO2/N2 Selectivity

Abstract Despite extensive studies of hyper-crosslinked polymers (HCPs) for carbon dioxide adsorption and separation, the fundamental role of aromatic precursor topology in governing localized gas confinement and molecular recognition has remained poorly understood. Herein, we de...

β-Sheet Antimicrobial and Antimycobacterial Peptides with a High Therapeutic Index by Employing the Repeats of a 5-Mer Segment of α-Helical Cytolytic Melittin

Abstract Despite strong antimicrobial activity, high haemolytic/cytotoxic properties, associated with its non-cell-selective membrane-lytic property and its large size prohibits considering bee-venom, α-helical, 26-residue, melittin as a lead molecule for antimicrobial-drug devel...

Magneto‐Photoactivated Gold Plasmonic Nano‐Islands and Quantum Dot Assemblies for ppt‐Level NO 2 Detection

ABSTRACT The intrinsic instability and limited chemical reactivity of metal nanoparticles have long restricted their direct integration in chemiresistive gas sensing. Here, we present a highly selective, tunable, ultra‐stable, and ultra‐sensitive NO 2 sensor derived from gold nan...

Molecularly Tuned PHFP- g -MA Anion-Exchange Membranes for High-Performance Vanadium Redox Flow Batteries

Abstract Developing membranes with high ion selectivity and long-term chemical stability is essential for advancing vanadium redox flow battery (VRFB) technologies. In this work, uncross-linked and cross-linked anion-exchange membranes (AEMs) based on PHFP grafted with 2-(dimethy...

Complete Isocyanide Triple Bond Scission by a Silylene Yields an Optoelectronic 1,3-Disilacyclobutene

Abstract The complete scission of strong triple bonds is a definitive hallmark of transition metals, typically remaining beyond the reach of main-group elements. Despite the success of silylenes in activating various inert linkages, the full fragmentation of the isocyanide C≡N mo...

Visible-Light-Responsive Pt–Cu(OH)2/ZnIn2S4 Catalysts for Efficient Nonsacrificial H2 Production from Water

Abstract Photoplatinized Cu(OH)2/ZnIn2S4 catalysts synthesized using a hydrothermal process and simple deposition methods are showing promising efficiencies in photosynthetic water-splitting reactions without any sacrificial agents present. The prepared Cu(OH)2/ZnIn2S4 with diffe...

LC3 forms functional nanoclusters on autophagosomes

Abstract Autophagosome biogenesis depends on the coordinated action of proteins and lipids. However, how LC3B organizes at high density and contributes to autophagy-associated functions remains unclear. Using molecular dynamics simulations and super-resolution microscopy, we show...

Lateral Size-Controlled Sulfur-Doped Graphene Aerogels with Tunable Electrical and Magnetic Properties

Abstract Graphene aerogel, an ultralight and highly porous material, shows promise for applications including energy storage, environmental sustainability, electronics, and biomedical fields. The roles of the lateral sheet size and heteroatom doping in graphene are key to its pro...

Design and simulation of high bandwidth compact folded waveguide slow wave structure for 0.65 THz traveling wave tube

This paper presents the design and simulation of a compact Folded Waveguide Slow-wave Structure for a 0.65 THz traveling-wave tube aimed at achieving a balance between bandwidth, output power, and fabrication-oriented structural simplicity. The proposed structure is analytically...

Interface-Engineered AgCoAc on Ti3C2T x MXene as a Bifunctional Electrocatalyst for Advancing CO2 Utilization and Oxygen Evolution

Abstract The escalating global demand for renewable energy sources and chemicals necessitates sustainable and resource-conscious production protocols that address future demands with a minimal environmental impact. The current study presents the viability of the AgCoAc@Ti3C2Tx-ba...

Controlled electro-alignment molecular dynamics in a high tilt angle ferroelectric liquid crystal cell

In a high tilt angle ferroelectric liquid crystal (HTAFLC), spontaneous polarization (Ps) minimization leads to the stripe domain formation with respect to the rubbing direction, arising from the smectic layer bending, limiting uniform alignment and hence practicality. A strategy...

Mass Spectral Investigation of Carbamates Using EI and CI Techniques

ABSTRACT N , N ‐Dialkyl pyridin‐3‐yl dimethylcarbamates (carbamates) are important precursor or degradation products of CWAs, including carbamate nerve agents (CMNAs). Therefore, the detection and identification of these carbamates are essential for the verification of CWC‐relate...

TRIM62 facilitates influenza A virus entry by regulating WASH-dependent endosomal trafficking

Abstract Endocytosis enables efficient cargo uptake while restricting uncontrolled cellular entry, yet how this balance is enforced during endocytic uptake remains poorly understood. Using influenza A virus (IAV) as a model cargo, we reveal a previously unrecognized role for the...

Dopamine alters macrophage metabolism promoting intracellular Mycobacterium tuberculosis survival

Dopamine (DA) is thought to aggravate progress of bacterial infections and enhance risk of intracellular bacterial infection like tuberculosis (TB). Though TB patients are known to present with high dopamine levels the causal link between them has remained unexplored. Mycobacteri...

Surface-Engineered 2D Hybrid h -BN/ g -C3N4 Nanocomposite for High-Efficiency Adsorptive Removal of Heavy Metal Ions from Aqueous Media

Abstract Heavy metal contamination in water sources is a significant concern for environmental and human health, necessitating the development of efficient, cost-effective, and sustainable removal methods. In this study, a surface-engineered hexagonal boron nitride (h-BN)/g-C3N4...

Modulating Sulfur Release Kinetics through Precursor Engineering for the Controlled Formation of 1 T /2H MoS2 Hybrids with Enhanced Charge Storage Properties

Abstract Molybdenum disulfide (MoS2) is a promising electrode material for electrochemical energy storage; however, its practical application is limited by the poor electrical conductivity of the thermodynamically stable 2H phase and the difficulty of achieving conductive 1T-rich...

IL-35 produced by dendritic cells via TIM-3-STAT3 signaling contributes to the development of visceral leishmaniasis

Visceral leishmaniasis (VL), a life-threatening parasitic disease caused by Leishmania donovani (LD), progresses primarily due to profound immunosuppression. However, the molecular and cellular mechanisms underlying this immune dysfunction remain poorly defined. In this study, we...

Nitrogen- and Sulfur-Co-Doped Reduced Graphene Oxide-Based Antifouling Electrochemical Sensor for the Detection of l -Tyrosine

Abstract Electrochemical sensing of l-tyrosine is challenging because its oxidation products and other biomolecules can adsorb onto the electrode surface, resulting in electrode fouling and deterioration of sensing performance. To address this limitation, nitrogen- and sulfur-co-...

Uracil-Thianthrenium Salts (Uracil-TT+BF4–) as a Coupling Partner in Sonogashira Cross-Coupling Reactions: Access to 5-Alkynyl Uracils and Synthetic Applications

Abstract Cross-coupling reactions are powerful tools for forging two different organic fragments via formation of C–C or C–heteroatom bonds. Herein, we for the first time synthesize a bench-stable cross-coupling reagent, uracil-TT+BF4–, for Sonogashira-type reaction to install an...