Institution
Academia Sinica
Recent research
- BiologyOpen access
Agrobacterium -mediated transient expression has revolutionised plant research, enabling numerous landmark discoveries across diverse areas of plant biology. Yet this powerful approach remains largely confined to solanaceous species, leaving most economically important crop famil...
- Engineering & TechnologyOpen access
Abstract This study introduces electrochemical sensor materials based on a conductive polymer PEDOT:PSS and a green-synthesized WO3 electrode (i.e., polymer composites of PEDOT:PSS@WO3-n, where n = 1–3 with three wt. ratios of PEDOT:PSS/WO3 = 1/1, 1/2, and 1/3, respectively) to d...
- Climate & EnvironmentOpen access
Earthquake prediction has long been considered one of the greatest challenges in the global scientific community due to the complex and uncertain nature of seismogenic processes, along with the prevailing consensus that earthquakes are inherently unpredictable. Here, we present a...
- AI & ComputingOpen access
Bounds on Treewidth via Excluding Disjoint Unions of Cycles
One of the fundamental results in graph minor theory is that for every planar graph $H$, there is a minimum integer $f(H)$ such that graphs with no minor isomorphic to~$H$ have treewidth at most $f(H)$. The best bound known for an arbitrary planar $H$ is ${O(|V(H)|^9\operatorname...
- Engineering & TechnologyOpen access
Abstract Hastelloy fiber paper (HAP) can be used as the oxygen evolution reaction porous transport layer (PTL) without using a catalyst layer in anion exchange membrane water electrolysis. It is combined with Ru on nickel fiber paper (NFP) (hydrogen evolution reaction PTL) to for...
- BiologyOpen access
The circulating lipidome in severe obesity
Severe obesity (SevO; BMI ≥ 40 kg/m 2 ) is rising globally yet remains understudied mechanistically. To characterize lipidomic alterations at the species level, we analyzed Border Health Research Cohort participants with fasting plasma lipidomics and genetic data, comparing SevO...
- Engineering & TechnologyOpen access
Developing electrodes that simultaneously enable rapid redox kinetics and efficient mass transport is critical for advancing high-performance vanadium redox flow batteries (VRFBs). Herein, a defect-rich three-dimensionally ordered macroporous MgCo 2 O 4 catalyst is integrated ont...
- Society & EconomicsOpen access
One linker, many relations: unifying Mandarin de via qualia, events and crosslinguistic insights
Abstract This paper argues that prenominal Mandarin de in XP- de -NP constructions serves uniformly as a polymorphic semantic linker, despite its varied syntactic environments. We propose that de introduces an underspecified relation variable, R, which connects the XP to the NP’s...
- Climate & EnvironmentOpen access
Abstract Per- and polyfluoroalkyl substances (PFASs) commonly occur as complex mixtures, yet the relationships among PFAS structure, cytotoxicity, and DNA strand-break responses remain incompletely resolved. We evaluated 11 PFASs selected to span environmentally prevalent and reg...
- BiologyOpen access
Taiwan oil millet (TOM; Eccoilopus formosanus) is a semi-domesticated orphan crop with potential as a resilient crop species and a model for C4 biology. However, the lack of an efficient tissue culture system has limited its use in genetic and functional studies. In this study, w...
- BiologyOpen access
Pancreatic cancer remains a lethal malignancy with few effective treatment options. MAPKAPK2, a downstream effector of p38 signaling, represents a potential target for disrupting tumor survival pathways. Structure-guided computational screening has become an important strategy fo...
- Engineering & TechnologyOpen access
Oxygen vacancy‐engineered CoSnO 3 /reduced graphene oxide (CoSnO 3 /rGO) serves as a durable cathode electrocatalyst for vanadium redox flow batteries (VRFBs). Structural and spectroscopic analyses confirm the formation of defect‐rich amorphous CoSnO 3 uniformly integrated with a...
- BiologyOpen access
Vertebrate organs undergo massive growth during the post-embryonic period. Yet, our understanding of how this organ-wide process is organized at single-cell resolution has been limited by an inability to monitor individual cells of different types throughout intact adult organs....
- Materials & Energy
ABSTRACT Seawater‐based artificial leaves are fundamentally constrained by anodic surface poisoning and insufficient photovoltage for bias‐free reaction under complex electrolytes. Here we report a pH‐gradient photoelectrochemical–electrochemical (PEC–EC) system that couples phot...
- BiologyOpen access
Abstract G protein-coupled receptors (GPCRs) are central physiological signal transducers and represent a primary class of therapeutic targets. While emerging evidence highlights a critical link between ligand-induced receptor conformations and pharmacological outcomes, the struc...
- Materials & EnergyOpen access
Abstract Fermi level pinning (FLP) fundamentally limits contact engineering in two-dimensional semiconductors, yet its intrinsic origin remains obscured by the presence of interfacial disorder and defect-induced gap states. Although theoretical models attribute FLP to metal-induc...
- Materials & EnergyOpen access
The inefficient carrier transport of earth-abundant tin sulfide (SnS), arising from its intrinsically low crystal symmetry, limits its thermoelectric performance at low temperatures. Here, the substitutional Ag+ doping modifies the Na-doped SnS crystal structure by reinforcing la...
- Biology
Abstract Sialic acid (Neu5Ac) is a monosaccharide terminating glycoconjugates, serving as ligands for lectins in health and disease. Tools to target sialyltransferases (STs) and neuraminidases (NEUs) are important in the study of sialoglycans. 3FaxNeu5Ac is a common ST inhibitor,...
- Materials & EnergyOpen access
Abstract Hastelloy fiber paper (HAP) exhibits excellent corrosion resistance, electrical conductivity, and structural robustness; however, its application as a porous transport layer (PTL) in water electrolysis systems remains relatively underexplored. In this study, a highly act...
- BiologyOpen access
Expanding horizons: a decade of synergy between light sheet and expansion microscopy
Abstract Over the past decade, biological imaging has been revolutionized by the convergence of two distinct technologies: expansion microscopy (ExM) and light sheet fluorescence microscopy (LSFM). ExM bypasses the diffraction limit of light by embedding biological specimens in a...