Yuka Otsuka

Novel orthotopic uterine leiomyosarcoma model demonstrated enhanced tumor growth, metastasis, and chemosensitivity compared to subcutaneous counterparts

Objective: Uterine leiomyosarcoma (uLMS) maintains a poor prognosis due to its aggressive behavior and limited therapeutic response. Preclinical progress is severely hindered by traditional subcutaneous models that often fail to metastasize, despite one-third of uLMS patients dis...

One Health genomic surveillance identifies potential genetic links of antimicrobial-resistant foodborne pathogens across sectors

Foodborne pathogens and antimicrobial resistance are major global health concerns. The integration and analysis of genomic surveillance data across human, animal, and environmental sectors remain a critical challenge in the study of foodborne bacteria. Here we investigate potenti...