Research works

Feasible geological carbon dioxide storage projections require updated cost and geological potential assumptions

Integrated Assessment Models project large-scale deployment of carbon dioxide geological storage across many climate change mitigation pathways. However, the feasibility of these projections - particularly concerning near-term scale-up rates - has been criticised. Here, we examin...

Interfacial Mechanisms and Shear-Key Improvement for an Assembled Integral Multi-Ribbed Composite Floor System

A novel assembled integral multi-ribbed composite floor system consisting of precast panels and a cast in situ topping has previously been validated through full-scale one-way and two-way slab experiments. Although the global load capacity of the system was initially verified, th...

Crosstalk between SELENOF and the unfolded protein response in breast epithelium dictates cell fate

Abstract SELENOF is an understudied selenoprotein that contains selenium in the form of selenocysteine. Our previous findings indicate that SELENOF likely functions as a tumor suppressor in breast cancer; however, its precise molecular role and regulatory mechanisms remain poorly...

In Situ High Shear Perturbation of Surface MolecularLayers with Neutron Reflectivity

Abstract We present the effect of in situ imposed shear on two adsorbed molecular layers using a flow cell that enables access to shear rates of up to 2 × 105 s–1 (shear stress: 2 × 102 Pa). The response of these molecular layers to shear is determined by the relative strength of...

Consent Is More Than “Multi-Factor Authentication”: From Intuited Cues to Communicative Accountability

To the Editor,Forrest and Ford (2026) make an important contribution by showing how young heterosexual men move between the formal language of affirmative consent and the less orderly realities of ...

Pyrazolo[3,4-b]pyridine: a privileged scaffold for the synthesis of anti-Alzheimer’s agents

Abstract Alzheimer’s disease (AD) is known to be the most prevalent neurodegenerative disorder that results in dementia and causes a variety of cognitive symptoms. There are many important aspects of AD that should be considered, even though the exact sequence of events is unclea...

Passages

Richard P. Gabriel's Patterns of Software: Tales from the Software Community is the kind of book that Passages, as a column, aspires to bring back to the attention of the software community. I am fairly sure this book, from 1996, is largely forgotten, but I think it deserves a wi...

Problem gambling and affected others: health, relational and economic outcomes across longitudinal trajectories in a population-based Swedish study

Abstract Background Exposure to another person’s gambling problems has been linked to a range of adverse outcomes among affected others (AOs); however, most evidence is based on cross-sectional studies. Less is known about how such outcomes vary over time and across different pat...

Effects of Morning and Evening Narrowband Blue Light and Myopic Defocus on Axial Length in Humans

Purpose To investigate the effects of morning and evening narrowband blue light exposure on axial length, and to examine the short-term effect of morning blue light combined with myopic defocus on axial length.Methods For objective 1, 18 individuals underwent 60 minutes of narrow...

Microfluidic engineering of CeO2/Peptide nanosheet-integrated bioactive hydrogel microspheres for multi-enzymatic biomimetic catalytic therapy of osteoarthritis

Osteoarthritis (OA) is a degenerative joint disease characterized by chronic inflammation and oxidative stress-induced cartilage degeneration, yet effective disease-modifying therapies remain limited. Herein, we report a CeO 2 /peptide nanosheet (CeP)-integrated hydrogel microsph...

Rab4b controls hepatic glucose production during fasting through glycophagy

Abstract Hepatic glucose production, essential for maintaining glycemia, is often altered in metabolic-associated fatty liver and glycogen storage diseases. Therefore, understanding the mechanisms that regulate the glucose production by hepatocyte is pivotal. Recent studies have...

Sewerage and rural disadvantage in England 1945–74

Abstract Prior to local government reorganisation in 1974, English rural councils were largely responsible for local sewerage services. In 1945, British national sentiment supported reversing interwar neglect of rural areas through investment in new housing and affiliated service...

Late Chronotype Is Associated With Dizziness and Postural Instability

OBJECTIVES: Sleep has been reported to be associated with dizziness. However, its relationship with chronotype, a behavioral manifestation of circadian rhythms reflecting individual variation in sleep-activity timing, has not been widely investigated. This study aimed to examine...

High‐Performance Laser Engine Enabling Synchronous Chirp Linearization for Wavelength‐Resolved FMCW Photonic Systems

ABSTRACT Integrated frequency‐modulated continuous‐wave (FMCW) photonic devices provide a promising route toward compact, fully solid‐state LiDAR systems. By incorporating passive dispersive structures, wavelength‐resolved FMCW architectures further exploit wavelength as an addit...

57. Concussion in Older Adults: Patient Characteristics and Key Clinical Considerations for Neuropsychologists

Abstract Purpose To describe the characteristics and clinical presentation of a large sample of concussed older adults, and to outline key considerations for providing specialty concussion care to this population. Method An EMR review was conducted of older adult patients (65-95y...

Uncertainty-Aware Bayesian Machine Learning for Thermo-Kinetic Parameter Estimation from Noisy Temperature Profiles

Temperature–time profiles obtained through thermistor-based monitoring provide a rich but noise-sensitive source of information for estimating kinetic and thermal parameters in exothermic batch reactions. Conventional workflows typically combine deterministic smoothing with numer...

When Metaphors Hurt or Heal: The Effects of Metaphor Use and Protagonist–Reader Similarity in Mental Illness Narratives on Stigma

= 522), the study finds that metaphor effectiveness highly depends on protagonist-reader similarity. Compared with literal narratives, war and journey metaphors increased hope and subsequently MI social interaction and MI help-seeking intentions, but only when protagonist-reader...

Digital and Green Transformations: Leveraging Global Value Chains in Belt and Road Initiative

ABSTRACT This study investigates the link between Global Value Chain (GVC), Digital Adoption Index, and Green Transformation Index across 89 Belt and Road (B&R) countries during 2004–2019. The study employs a multi‐regional input–output framework and the System Generalized Me...

Oxidative Stress Modulation and Organ Protection by Mondia whitei: Phytochemistry, Mechanisms, and Therapeutic Potential

<ns5:p> <ns5:italic>Mondia whitei</ns5:italic> (Hook.f.) Skeels is an indigenous African medicinal plant widely utilized in traditional medicine for the management of reproductive disorders, gastrointestinal ailments, inflammation, and general health promotion. Increasing scienti...

Modernizing the TRIAD ecological risk assessment framework. Part II: Omic methods for high-resolution biological risk indicators

<ns5:p>The TRIAD framework is a widely used approach to assess site-specific ecological risk by integrating three Lines of Evidence (LoE): chemical, ecotoxicological, and ecological. As environmental contamination grows increasingly complex, the framework requires modernization i...