Research works

Acute mental stress-induced adrenergic reactivity profiles predict distinct cardiometabolic risk trajectories over three years: the SABPA study

OBJECTIVES: We previously characterised acute mental stress-induced alpha (α)- and beta (β)-adrenergic-haemodynamic reactivity profiles cross-sectionally and related them to unique cardiometabolic risk outcomes. Whether these profiles predict future cardiometabolic risk remains u...

Enhancing Coastal Safety with AI: A Lightweight Deep Learning Framework for Rip Current Segmentation via Architectural Co-Design and Model Compression

Rip currents pose significant threats to coastal safety and to autonomous marine vehicles operating nearshore. However, deploying high-precision monitoring models on resource-limited platforms remains challenging. This paper proposes a comprehensive framework that combines a nove...

The Influence of Organo-Mineral Fertilization on P and Ca Management in Festulolium braunii (K.Richt.) A. Camus and Their Content in the Soil

The management of spent mushroom substrate (SMS) from the cultivation of the button mushroom Agaricus bisporus poses a significant environmental challenge in Poland. This study analyzed the effect of applying SMS on the phosphorus and calcium content in Festulolium braunii plants...

Overland corridors as a substitute for ocean freight in China–Europe trade

Overland corridors offer alternatives to ocean freight, but rising railway traffic does not by itself demonstrate maritime substitution. This study evaluates the scale, direction, and commodity composition of reported modal reallocation in China–European Union trade. An original...

Surface-Data-Driven Multiple Elimination in the Common-Midpoint Domain and Its Application to Land Seismic Data

Surface-data-driven multiple elimination methods directly use surface data to predict and eliminate multiples without requiring a detailed subsurface velocity model, but can be computationally expensive and not always straightforward on land datasets. We present a unified framewo...

Raman Spectroscopy of Laser-Micro-Annealing-Induced Structural Changes in Ti-6Al-4V

This short study presents the results of micro-Raman investigations performed on the alloy Ti-6Al-4V, which was additively manufactured via metal fused filament fabrication (MF3). Local laser micro-annealing was applied at different power intensities to distinct regions. The appl...

Dietary nutrients and biotics protect against injury to intestinal epithelial barrier in alcohol use disorder: A narrative review

The intestinal epithelial barrier is anatomically and functionally distinct and specifically refers to the barrier formed by epithelial cells (enterocytes) and associated junctional complexes (tight junctions, adherens junctions, and desmosomes). The junctional complex is compose...

Low-Velocity Impact Response and Residual Burst Strength of Fiber-Wound Composite Pressure Vessels

The increasing use of lightweight fiber-wound composite pressure vessels in energy-storage and transportation applications has heightened the need to understand impact-induced structural damage and the associated degradation in residual load-bearing capacity. Despite their superi...

Obstetric Pharmacomicrobiomics

Pregnancy is characterized by physiologic, metabolic, immunologic, and microbial adaptation. Medication use during pregnancy is common. Yet, therapeutic response often remains unpredictable because obstetric pharmacology has historically focused on pharmacokinetic changes while p...

What Is the Best Word to Describe AI Uncertainty: Confidence, Certainty, Reliability, or Accuracy?

AI systems are increasingly common in decision-making tasks. However, these systems often generate probabilistic responses, resulting in uncertainty in their outputs. Understanding this uncertainty can help users make robust decisions, such as when to trust the agent and whether...

Correlation analysis between preoperative inflammation-nutrition-related indices and the risk of pancreatic fistula formation following distal pancreatectomy

Objective To investigate the associations of preoperative C-reactive protein-to-albumin ratio (CAR), inflammatory burden index (IBI), and C-reactive protein-albumin-lymphocyte (CALLY) index with clinically relevant postoperative pancreatic fistula (CR-POPF) after distal pancreate...

Non-sewered sanitation systems reshape microplastics into chemically complex and reactive contaminants

Non-sewered sanitation systems (NSSSs) are gaining global attention as decentralized solutions, yet the transformation of microplastics (MPs) within these systems remains poorly understood. Here, we investigate MP characteristics in the influent and effluent of two NSSSs using la...

Mannose-Functionalized Polymeric Micelles Target CD206-Expressing Macrophages Within Human Tuberculosis Granulomas and Improve Isoniazid Delivery

Background: Latent tuberculosis infection (LTBI) remains a global health challenge, in part due to the ability of Mycobacterium tuberculosis (Mtb) to persist within granulomatous lesions where drug exposure may be limited. Because granulomas are heterogeneous structures composed...

A hybrid deep feature extraction and ensemble learning framework for robust multi-class ECG image classification

Abstract ECG signals, the electrical activity of the heart, play a vital role in early identification of cardiovascular diseases (CVDs), which are currently the leading cause of death across the world. However, manual detection of ECG images can be time-consuming, prone to human...

Timing Matters: Preoperative Lumbar Epidural Steroid Injection and Long-Term Outcomes Following Single-Level Posterior Lumbar Fusion

Study Design Retrospective Cohort Analysis. Objective CESIs are a mainstay of nonoperative treatment for degenerative lumbar spine disease. As increasing numbers of patients undergo sPLF after receiving CESIs, understanding their impact on surgical outcomes is essential. The obje...

Near point-of-care nucleic acid amplification tests (NPOC-NAATs) using respiratory specimens for detection of pulmonary tuberculosis

RATIONALE: Near point-of-care nucleic acid amplification tests (NPOC-NAATs) are a new class of diagnostics that can be used for tuberculosis diagnosis. NPOC-NAATs are suitable for use in peripheral levels of healthcare systems as they are battery-operated instrument-based tests w...

The combination of yeast cell wall and Heyndrickxia coagulans SANK70258 maximized butyrate production in an in vitro gut model

Abstract In recent years, increasing attention has been paid to synbiotic formulations comprising prebiotics and probiotics. Yeast cell walls (YCW) constitute a well-known industrial material with partial prebiotic effects. Its potential as a synbiotic agent that can add value to...

Tacrolimus attenuates BCL-2/BAX-mediated chondrocyte apoptosis and cartilage matrix degradation in experimental osteoarthritis

Osteoarthritis is a progressive whole-joint disease characterized by cartilage matrix degradation, synovial inflammation and impaired chondrocyte survival. Current pharmacological treatments mainly relieve symptoms and do not reliably prevent structural progression. Here, we inve...

Propionibacterium cheese and bone turnover in active young adults: a randomized-controlled trial

Abstract Introduction Young physically active individuals exposed to prolonged physiological stress and low energy availability are prone to reduced gonadal steroid protection and increased bone turnover. Nutritional strategies that favor positive bone remodeling balance are of c...

A lightweight attention-enhanced intrusion detection method for anomalous network traffic analysis

Network intrusion detection in complex traffic environments requires a careful balance between detection performance and computational efficiency, particularly when models are intended for resource-constrained scenarios. Existing deep learning-based intrusion detection methods ca...