Research works

PHARMACOVIGILANCE AND ADVERSE DRUGS REACTION

Pharmacovigilance, a scientific discipline of the public health and medicine. The primary goal is the detection, evaluation, understanding and prevention of ADRs and other drug-related problems. ADRs are a significant cause of patient morbidity and mortality, prolongs hospitaliza...

GREEN PHARMACY: ECO-FRIENDLY APPROACHES IN PHARMACEUTICAL MANUFACTURING – A REVIEW

Green pharmacy is an emerging approach that integrates the principles of environmental sustainability into pharmaceutical research, manufacturing, distribution, use, and disposal of medicines. The pharmaceutical industry contributes significantly to environmental pollution throug...

ASSOCIATION OF ANTIBIOTIC RESISTANCES AMONG MYCOBACTERIUM TUBERCULOSIS AMONG SALAH-ALDEEN COMMUNITY

Background: Mycobacterium tuberculosis, the etiological agent causing tuberculosis, is one of the most common contagious diseases that poses a serious threat to human health. As per the recent WHO report, TB incidence throughout the world amounts to 10.7 million and the total dea...

SUCCESSFUL GLYCEMIC CONTROL WITH MICON GOLD FACILITATING GRADUAL TAPERING OF ORAL HYPOGLYCEMIC AGENT - A CASE REPORT

Madhumeha is described under Prameha in Ayurveda and resembles Type 2 Diabetes Mellitus. Long-term hyperglycemia leads to microvascular and macrovascular complications. Ayurvedic formulations such as Vasant Kusumakar Rasa have been traditionally used in the management of Madhumeh...

MACHINE LEARNING IN PHARMACEUTICAL FORMULATION DEVELOPMENT

The use of ML algorithms in pharmaceutical research has enabled remarkable progress, especially by circumventing the problems inherent in the trial and error method of drug development. This review is intended to highlight the growing use of machine learning algorithms such as ar...

DEVELOPMENT OF HPMC-BASED MATRIX TABLETS FOR THE SUSTAINED RELEASE OF METFORMIN HYDROCHLORIDE

537 million individuals globally are affected by type 2 diabetes mellitus (T2DM) India has the highest number of cancer cases worldwide. Metformin Hydrochloride is classified as a biguanide of BCS Class III. It is the first oral agent used to treat diabetes. Side-effects of this...

A REVIEW ON FORMULATION AND EVALUATION OF TOPICAL GEL OF CLINDAMYCIN FOR ACNE VULGARIS

Acne vulgaris is one of the most common chronic inflammatory skin disorders affecting adolescents and adults worldwide. It develops due to excessive sebum production, follicular hyper keratinizati on, bacterial colonization by Cutibacterium acnes, and inflammation. Topical drug d...

MANAGEMENT OF OVERT HYPOTHYROIDISM WITH A SINGLE DOSE OF HOMOEOPATHIC MEDICINE PHOSPHORUS – AN EVIDENCE BASED CASE REPORT

INTRODUCTION: Hypothyroidism is a hypo-metabolic state resulting from inadequate secretion of thyroid hormones. It is the second most common endocrine disorder among women and leading cause of menstrual abnormalities in all age group. Levothyroxine is the standard lifelong mode o...

A REVIEW OF UPAVANAVINODA: INSIGHTS INTO VRIKSHAYURVEDA FOR SUSTAINABLE AGRICULTURE AND ENVIRONMENTAL HEALTH

The domestication and cultivation of plants have been integral to human civilization since ancient times. In Ayurveda, Vrikshayurveda represents the traditional science of plant health and sustainable cultivation. Among its classical texts, Sharangadhara Paddhati (13th century CE...

IBUPROFEN-LOADED CORE-SHELL NANOPARTICLES FOR OSTEOARTHRITIS: A REVIEW

Core-shell nanoparticles present a revolutionary approach in local nanomedicine, featuring highly adjustable physicochemical structures. The advanced bimodal nanoparticles contain a specifically designed hydrophobic core for the encapsulation and molecular stabilization of the th...

FORMULATION AND IN-VITRO CHARACTERIZATION OF TRANSFEROSOMAL GEL FOR ENHANCING THE TRANSDERMAL PERMEATION OF ACECLOFENAC

Background: Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of rheumatoid arthritis, osteoarthritis, and other inflammatory conditions. However, its oral administration is associated with gastrointestinal irritation, first-pass metaboli...

FORMULATION AND EVALUATION OF IMMEDIATE-RELEASE OFLOXACIN TABLETS PREPARED BY WET GRANULATION METHOD

The present study was undertaken to formulate and evaluate immediate-release (IR) tablets of Ofloxacin using the wet granulation method. Six formulations (F1–F6) were prepared with different concentrations of pharmaceutical excipients to obtain tablets with satisfactory physicoch...

ASSESSMENT OF SERUM ELECTROLYTES, UREA AND CREATININE IN A COMPARATIVE STUDY OF SOME HYPOGLYCEMIC DRUGS ON STREPTOZOTOCIN INDUCED ALBINO WISTAR RATS

Type 2 diabetes mellitus is the 7th leading cause of death in United States of America. One way by which this disease can be managed is through the use of hypoglycemic drugs. This study aims to investigate the effects of some hypoglycemic drugs such as Biguanide (metforming), sul...

EVALUATION OF ANTIHELMINTIC ACTIVITY OF COMBINATION OF CARICA PAPAYA AND TINOSPORA CORDIFOLIA LEAF EXTRACTS USING PHERETIMA POSTHUMA

The present study was carried out to evaluate the antihelmintic activity of aqueous leaf extracts of Carica papaya and Tinospora cordifolia individually and in combination using Pheretimaposthuma as an experimental model. The extracts were prepared using the aqueous maceration me...

FORMULATION AND EVALUATION OF COLLAGEN-BASED QUERCETIN CREAM

Background: Inflammation is a fundamental pathophysiological feature in numerous chronic diseases including arthritis, dermatitis, and wound-related conditions. Synthetic anti-inflammatory agents, though effective, are associated with significant adverse effects such as gastroint...

PREDICTORS OF SURGICAL MORBIDITY IN PEDIATRIC HEPATIC HYDATID DISEASE: A RETROSPECTIVE STUDY FROM THE JORDANIAN ROYAL MEDICAL SERVICES

Background: Pediatric hepatic hydatid disease is a major health problem in various regions. The concurrent pulmonary involvement in children is considered common and increase the postoperative risk. In our study assessed if pulmonary co-involvement independently predicts surgical...

FORMULATION AND EVALUATION OF POLYHERBAL DENTAL PASTE OF MEDICINAL EXTRACTS BY USING ALLIUM CEPA AND KALONJI SEEDS

Oral diseases, including dental caries, plaque, gingivitis, and halitosis, are among the most prevalent health problems worldwide. Although conventional toothpastes effectively maintain oral hygiene, prolonged use of products containing synthetic chemicals may be associated with...

TRIVIDHA CHIKITSA: FROM SACRED PETALS TO PRACTICE IN STREE ROGA AND PRASUTI TANTRA

Introduction: Flowers possess unique therapeutic qualities that make them highly suitable for women’s healthcare. Their natural origin, gentle action, and compatibility with the female body enable their safe use across different stages of life, including adolescence, reproductive...

INTRANASAL GEL TO TREAT PARKINSON DISEASE

Parkinson disease the second most common neurodegenerative disease caused due to the degeneration of dopaminergic neuron in substantial nigra results in the depletion of striatum dopamine.[1] The symptoms of this disease are classified into motor and non-motor symptoms. The motor...

EFFICACY OF AYURVEDIC TREATMENTS IN STRESS MANAGEMENT

The significance of stress in the development of various diseases is acknowledged in both Ayurvedic knowledge and contemporary medicine. In Ayurveda, stress is known as sahasa. Due to sahasa leading to ojahksaya, or decreased immunity, the body is rendered more susceptible to var...