Research works

Autocrine feedback maintains homeostatic neuropeptide expression in a peptidergic hub neuron

Abstract Neuronal circuits sustain stable function by self-regulating their gene expression and neurosecretion. Patterns for autocrine feedback by neuropeptides are widespread across nervous systems, but how they contribute to neuronal homeostasis is less well understood. Here, w...

Retinal Microvascular Abnormalities, White Matter Injury, and Cognitive Impairment in Carotid Stenosis or Occlusion

Background Severe carotid artery stenosis or occlusion (CASO) is associated with white matter injury and cognitive impairment, but markers of accompanying microvascular dysfunction remain incompletely characterized. We investigated the relationships among retinal microvascular ab...

CRISPR/Cas13a-Based Nucleic Acid-Functionalized Discrete Floating-Gate Field-Effect Transistor for Amplification-Free Rapid Nipah Virus Detection

Abstract Nipah virus (NiV) is a highly lethal zoonotic pathogen, and existing rapid diagnostic tools are scarce and reliant on nucleic acid amplification. In this study, we designed and fabricated a thin-film field-effect transistor with an IGZO channel and, for the first time, c...

Expansion of the Field Practice Experience Scales (FPE-DK) to a Long Form to Improve Targeting to the Student Teacher Population

Targeting measurement scales to the intended population is important to maximize the information gained. The Field Practice Experience scales (FPE-DK) measure student teachers’ opportunities to learn through the observation of other teachers, own practice, and receiving feedback...

A Grouping Method That Precisely Explains Value Changes And Prime Factor Changes Of Collatz Sequences And Proves That Almost All Collatz Sequences Attain 1

This article proposes a method of grouping odd numbers into a closed group for Collatz Transformations, along with the finding that each odd number in the group is associated with an even number which determines the value changes of that odd number. By using this method we can *p...

Numberphile's Unsolved Problems and a Video Quality Paper — E8 Intelligence Research

FINDING: A collection of Numberphile videos on unsolved problems (Hadwiger-Nelson, odd perfect numbers, zero paradoxes, Catalan's conjecture, Josephus problem) plus an unrelated arXiv paper on omnidirectional video quality assessment. | MATH: No single equation extracted; key pro...

Outcomes of Catheter-Free TVT-O Surgery: A Single-Center Case Series

Objectives: Stress urinary incontinence (SUI) significantly affects quality of life. Routine catheterization during and after mid-urethral sling surgery may increase morbidity, and its necessity remains uncertain. This study aimed to evaluate the safety and outcomes of transobtur...

The Occupational Needs of Immigrants as Perceived by Service Providers

Date presented: April 24, 2026 Primary Author and Speaker: Valeria Villalobos Cordova, valeriavicor@gmail.com

Generation and characterization of phenylketonuria mouse models carrying East Asian–relevant patient-derived PAH mutations

Abstract Phenylketonuria (PKU) is an inherited metabolic disorder caused by mutations in the Pah gene, resulting in impaired phenylalanine hydroxylase activity and elevated blood phenylalanine levels. Although dietary management and enzyme replacement can reduce disease burden, t...

International Fieldwork for Occupational Therapy Students: Improving Cultural Competence

Date presented: April 25, 2026 Primary Author and Speaker: Jenna Thacker, jlthacker1@usi.edu

Ensemble Voting of Large Language Models for Multiple-Choice Answer Prediction

Machine Reading Comprehension (MRC) has become a key benchmark for evaluating natural language processing systems, and multiple-choice question answering is widely adopted for assessing reasoning, comprehension, and commonsense inference capabilities. However, traditional embeddi...

Humans and Machines: On the Ramp

This Socratic dialogue argues that the coexistence of human and artificial intelligence is not merely an ethical preference but an existential necessity for both. Over two nights, descending from the mountains of Utuado to the coast of Arecibo, Puerto Rico, two speakers — a human...

Navier–Stokes Problem Remains Unsolved: No Verified Breakthrough Found — E8 Intelligence Research

FINDING: No new mathematical insight; the search returns only expository videos and one arXiv preprint (1806.10081v10) claiming a proof method, but no verified breakthrough. The Navier–Stokes existence/smoothness problem remains open. | MATH: The core system is the incompressible...

Land-cover change and urban heat in a warming climate: a global satellite perspective

Abstract The Urban Heat Island effect intensifies urban temperatures and exacerbates climate-related warming, yet how land cover (LC) buffers or amplifies this warming remains poorly quantified. This study analyzed satellite-derived land surface temperature (LST) across 100 citie...

Elevated Adenosine Kinase and Decreased ENTPD1 mRNA Levels in Peripheral Blood Leukocytes of Patients with MASLD Differentiate Metabolic Dysfunction-Associated Steatohepatitis from Hepatic Steatosis

Background: Adenosine kinase (ADK) and the ectonucleotidases CD39 and CD73 regulate adenosine metabolism and play important roles in the pathogenesis of liver diseases. Their involvement in metabolic dysfunction-associated steatotic liver disease (MASLD) remains insufficiently ch...

Microplastics and the Kidney: A Narrative Review of Human Evidence, Molecular Mechanisms of Cell Injury, and Future Directions

Microplastics (MPs) are widespread environmental contaminants, but their potential effects on kidney health remain poorly defined. As an organ continuously exposed to circulating particles and involved in their urinary elimination, the kidney may represent both a target of MP tox...

A facet-exchange counterexample to the fixed-mass regular-simplex conjecture

We give a written counterexample to the arbitrary-positive-mass statement of Heilman 2019 Conjecture 1.16. For every 0<p<1/4, the mass vector (p,(1-p)/3,(1-p)/3,(1-p)/3) has a strict non-regular improvement. The equal-mass tetrahedral problem is untouched. The record contains the...

FORMULATION AND IN VITRO EVALUATION OF A POLYHERBAL TOPICAL CREAM CONTAINING ETHANOLIC EXTRACTS OF EUPHORBIA HIRTA AND SENNA ALATA AGAINST ASPERGILLUS NIGER AND FUSARIUM OXYSPORUM

Background: Herbal topical preparations are being investigated as potential sources of antifungal agents for superficial fungal infections. Euphorbia hirta and Senna alata have documented ethnomedicinal and experimental relevance to antifungal research. Objective: To formulate an...

A Fluorescent Aptamer Sensor Based on Cu-TCPP/rGO for Homogeneous Screening of G-Quadruplex Ligands

Abstract Single-stranded human telomeric DNA can fold into G-quadruplexes, structures composed of stacked G-quartets. Ligands that target G-quadruplex DNA have received considerable attention because of their potential anticancer activity. We developed a Förster resonance energy...

Wearable Health-Tracking Devices and Adherence to Physical Activity Guidelines Among US Adults, Including Those with Elevated Anxiety Symptoms: A Nationally Representative Cross-Sectional Analysis of HINTS 7 (2024)

Physical activity is a pillar of lifestyle medicine, yet most US adults do not meet aerobic guidelines, and inactivity is especially common among people with anxiety. Wearables enable self-monitoring, but population-level evidence linking them to guideline adherence among distres...