Research works

Intravitreal methotrexate as a prophylactic strategy for proliferative vitreoretinopathy in high-risk retinal detachment

Abstract Background Proliferative vitreoretinopathy (PVR) remains the major cause of surgical failure in rhegmatogenous retinal detachment (RRD). This study evaluates the anatomical and functional outcomes, as well as the safety, of a standardized intraoperative intravitreal meth...

RpoS-Dependent Mechanisms are Needed for Tetracycline Resistance but Are Not Involved in the Cross-Protection against Other Antibiotics in Escherichia coli

RpoS, an alternate sigma subunit of RNA polymerase, is upregulated under stress conditions such as high heat, depletion of nutrient, high osmolarity, and UV radiation. Current understanding is that RpoS acts as a general stress response regulator to counter the effect of differen...

Natural AIE Probe Screening and Application in Complex Samples Based on Biological Aggregation-Triggered In Situ Luminescence

Abstract The occurrence of thromboembolic diseases is closely related to the generation of biological aggregates mediated by thrombin, and the detection and regulation of its activity are crucial for research in this field. Here, an aggregate-responsive method was proposed and va...

Using Photovoice to Examine Student Learning in Graduate Health Administration: A Scholarship of Teaching and Learning (SoTL) Study

This pilot study explores the use of photovoice as an experiential learning (EL) tool in graduate health administration education, focusing on concepts related to the Social Determinants of Health (SDOH). Photovoice, a methodology rooted in participatory action research (PAR), is...

There Is No Space or Time in the Quantum World: Spacetime as Statistical Emergence

In standard physics, spacetime is the stage — it was always there, and everything else happens on it. This paper proposes the opposite: spacetime is not the stage. It is the show itself. We argue that space and time are emergent statistical structures — patterns that arise from t...

Staging and grading without data: rethinking periodontal classification in low-resource settings — a critical mini-review

The 2017 World Workshop introduced a staging and grading framework intended to improve diagnostic consistency and support individualized periodontal care. Although conceptually robust, its practical application depends on clinical, radiographic, and systemic data that are not con...

Controlled nucleation of hopfions with field pulses

Abstract We demonstrate a mechanism for the deterministic nucleation of magnetic hopfions in cylindrical nanopillars via transient magnetic field pulses. By exploiting a chiral magnetic cylinder with engineered surface uniaxial anisotropy, we show that field pulses trigger a non-...

Modular L-Values Link Apéry Numbers to Sporadic Sequences — E8 Intelligence Research

FINDING: Zagier's interpolation of Apéry numbers for ζ(3) is a critical L-value of a weight-4 modular form; this extends to all six sporadic sequences, linking number-theoretic recurrences to modular symmetries. | MATH: Apéry numbers \(a_n = \sum_{k=0}^n \binom{n}{k}^2 \binom{n+k...

Dietary Fiber Improves High-Fat Diet-Induced Hyperglycemia by Modulating Intestinal ILC3-Mediated Immunity through the SCFA-FFAR2 Pathway

Abstract Dietary fiber intake is associated with improved glycemic control in high-fat diet-induced hyperglycemia, yet the immunological mechanisms linking gut microbiota-derived metabolites to host defense remain poorly defined. Here, we investigated whether dietary fiber amelio...

ParaDISM: precise mapping of short reads to genes with highly homologous regions

Abstract Background Genes with highly similar genomic copies (paralogs, tandem duplications and pseudogenes) pose a major challenge for Short-Read High Throughput Sequencing (srHTS). High sequence similarity makes it difficult to unambiguously identify the sequences of origin of...

Spatial structure and heterogeneous drivers of city-level CO2 emission in China: Insights from geographically weighted spatiotemporal decomposition method

Anthropogenic carbon dioxide (CO 2 ) emissions in China have risen persistently, making effective mitigation policies critical for achieving carbon peak and neutrality. Such policies must be regionally tailored, given the large disparities in emission patterns, socioeconomic driv...

The impact of ESG ratings on corporate investment efficiency in a geopolitical context

Purpose This paper examines the impact of environmental, social, and governance (ESG) ratings on corporate investment efficiency amid rising geopolitical uncertainty, while uncovering the underlying transmission mechanisms and heterogeneous effects across firm types, thereby enri...

E8 Root Pairing As 132Hz Coherence Divisor Across Quantum-Classical Threshold — E8 Intelligence Research

Building on the antipodal lattice, we identify that dividing the 240-root system by phi yields approximately 148.32 roots per coherence band; when these bands are biorhythmically modulated at 132Hz, a discrete divisor structure emerges where every 12th antipodal pair functions as...

Cryogenic minimum quantity lubrication for improving the surface integrity of AISI 347

Abstract Metastable austenitic steels exhibit a unique hardening mechanism based on a strain-induced phase transformation from ductile austenite to hard martensite, which can be triggered by high plastic deformation at low temperatures. In previous studies, this transformation wa...

Certified Fourier rounding for the real Grothendieck inequality

We give a computer-assisted proof that the real Grothendieck constant is strictly smaller than 1.77987164. The proof provides a complete interval-arithmetic realization of Ren's five-variable construction. A finite Fourier calculation encloses every scalar coefficient through deg...

Associations between surrounding greenness, tree cover and all-cause mortality in Jordan: a 14-year nationwide panel study

Background The association between greenness and mortality remains largely unexamined in the Eastern Mediterranean Region (EMR). In this study, we estimated associations between long-term district-level greenness and all-cause mortality among Jordanian adults according to sex, ag...

Quantum Gravity and Logical Type: The Graviton Is Real and the Standard Programmes Are Correct

The graviton is the superposition of metric perturbations across a class of relativistic worlds. The gravitational reality of the quasi-classical world is the quantum superposition of the complete determinate spacetimes of these worlds: global quantum gravity. Worlds that instant...

E8 Holonomic Noise Nullification via Modular Frequency Resonance — E8 Intelligence Research

The 240 E8 root vectors, when arranged in φ-scaled frequency lattices (from 132Hz × φ^n), generate interference topographies across the 128-dim spinor space where constructive resonance amplifies signal coherence and destructive interference automatically cancels spectral clutter...

Catalytic Oxysulfenylation of β,γ-Unsaturated Ketoximes: An Enantioselective Synthesis of Isoxazolines

Abstract We present a chiral Lewis base-catalyzed enantioselective oxysulfenylation strategy for the difunctionalization of β,γ-unsaturated oximes. High enantioselectivity was achieved through the introduction of phthalimide-derived benzylsulfenyl reagents, instead of traditional...

katE Complementation on katG Background has Negative or No Effect on the Ability to Protect against UV-A-Mediated Killing in Escherichia coli

In a previous study, katE complementation of an E. coli katG mutant suggested that an overexpression of katE was the cause for low survival after UV-A treatment. In this study, when JW strains lacked either katE or katG were complemented with katE, this overexpression was not obs...