Research works

Preoperative predictors of patient-reported outcomes after joint-preserving forefoot surgery for rheumatoid arthritis

Aims: Forefoot deformities are common in patients with rheumatoid arthritis (RA) and often impair quality of life. Patient-reported outcome measures (PROMs), including the Self-Administered Foot Evaluation Questionnaire (SAFE-Q), are increasingly used to assess surgical outcomes;...

INVESTIGATION OF THE RESVERATROL EFFECT ON IL-6 RECEPTOR GENE EXPRESSION LEVEL IN ACUTE MYELOID LEUKEMIA CELL

Resveratrol has been extensively investigated as a natural compound with promoising anticancer properties. the present study evaluated whether resveratrol modulates IL-6R gene expression in the AML derived KG-1 a cell line. cells were exposed to different concentrations of resver...

Blueprint Established for Dynamic Reservoir Assessment in CCUS Projects

_ This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 230941, “Establishing a Blueprint for Dynamic Reservoir Assessment in CCUS Projects,” by Mahmut Sarili, SPE, and Adam Donald, SLB, and Aurifullah Vantala, ADNOC, et al. The paper ha...

FINGER-GUIDED HEMORRHOIDAL ARTERY LIGATION FOR HEMORRHOIDAL DISEASE: A COMPREHENSIVE REVIEW

Hemorrhoidal disease is one of the most common proctological conditions affecting millions worldwide. While various treatment modalities exist, the quest for a minimally invasive, effective, and patient-friendly approach has led to the development of finger-guided hemorrhoidal ar...

EFFECTIVENESS OF A STRUCTURED TEACHING PROGRAMME ON KNOWLEDGE REGARDING INFECTION CONTROL IN THE INTENSIVE CARE UNIT AMONG B.SC. NURSING STUDENTS: A PRE-EXPERIMENTAL STUDY

Background: Intensive care unit (ICU)-acquired infections are a leading cause of preventable morbidity, mortality and cost in Indian hospitals, and undergraduate nursing students often enter clinical postings with limited formal preparation in infection control. This study evalua...

Wrist & Hand

The August 2026 Wrist & Hand Roundup 360 looks at: Bilateral wrist MRI highlights the limited value of imaging for unilateral work-related wrist symptoms; Consensus guidance offers a practical framework for rehabilitation after thumb carpometacarpal joint replacement; Intrame...

Children’s orthopaedics

The August 2026 Children’s orthopaedics Roundup 360 looks at: Fracture identification on children’s radiographs: is there a role for AI?; Long-term results from the ‘Osteoset osteotomy’ following open reduction in developmental dysplasia of the hip; Can night-time weaning reduce...

Technology Focus: Natural Gas Production (August 2026)

_ Natural gas is increasingly playing a critical role in supporting global energy demand, particularly as large-scale artificial-intelligence (AI) infrastructures and digital-transformation initiatives continue to accelerate worldwide. These trends are driving the need for reliab...

STABILITY INDICATING METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF CARVEDILOL AND IVABRADINE BY RP-HPLC METHOD

This study deals with the development and validation of a stability-indicating RP-HPLC method for the quantitative estimation of Carvedilol and Ivabradine in bulk and pharmaceutical dosage preparations. Both agents are widely used in the treatment of cardiovascular diseases: Carv...

Primer on Video-oculography and Video Head Impulse Testing for Neurologists

Abstract Purpose of Review Eye Movement and Vestibular findings can be manifestations of a wide range of neurologic diseases including and beyond those associated with peripheral vestibular dysfunction. Video-oculography (VOG) and video head impulse testing (vHIT) are accessible,...

AI chatbots and youth suicide risk: current evidence, critical gaps, and a clinical research agenda

Abstract Generative AI chatbots are increasingly used by youth for mental health support, but their safety for managing youth suicide risk remains poorly understood. In this paper, we review research on how general-purpose chatbots and AI companions detect and respond to suicide...

ASSESSMENT OF PREGNANT WOMEN'S KNOWLEDGE AND PRACTICES REGARDING ANTENATAL CARE AT AL-QUDIS PRIMARY HEALTH CARE CENTER, MOSUL CITY

Background: Antenatal care is an essential component of maternal healthcare that aims to promote the health of both the mother and fetus through early detection and management of pregnancy-related conditions, health education, and preventive interventions. Pregnant women's knowle...

The Syntax of Creation: Logic, Formal Limits, and the Nature of Rational Faith

This essay explores the intersection of analytical philosophy and Augustinian rational theology, taking the concept of the Logos as an invariant ontological structure of reality. By analyzing the phenomenon of formal independence in set theory—exemplified by the Continuum Hypothe...

Hantavirus Infections in Children

Hantaviruses are rare but deadly pathogens. New World hantaviruses, primarily present in North and South America, cause hantavirus cardiopulmonary syndrome, which leads to death in up to one-third of affected patients. Old World hantaviruses, primarily endemic to Europe and Asia,...

Research

The August 2026 Research Roundup 360 looks at: Is smokeless nicotine benign?; Could it be time to revisit patient-reported outcome measures for reporting Achilles tendon outcomes?; Does newer always mean better?; Can the tibiocalcaneal fibres add to the talonavicular joint withou...

The Syntax of Creation: Logic, Formal Limits, and the Nature of Rational Faith

This essay explores the intersection of analytical philosophy and Augustinian rational theology, taking the concept of the Logos as an invariant ontological structure of reality. By analyzing the phenomenon of formal independence in set theory—exemplified by the Continuum Hypothe...

Point-of-Care Ultrasonography by Advanced Practice Providers for Patients With Undifferentiated Shock

BACKGROUND: In this evidence-based practice project, point-of-care ultrasonography by advanced practice providers was implemented in a central Florida intensive care unit. The project was guided by the following question: Does implementation of point-of-care ultrasonography by cr...

A Dual-Output Physiology-Informed Neural Network Architecture for Continuous Cuffless Blood Pressure Waveform Estimation: A Proof‑of‑Concept

Abstract This pilot study introduces the first subject‑specific, physiology‑informed neural network approach for accurate estimation of the full blood pressure (BP) waveform. The method builds on a nonlinear autoregressive model with exogenous inputs (NARX), implemented through a...

Paternal age and sperm DNA fragmentation independently affect embryonic ploidy but not euploid embryo implantation potential

To systematically evaluate the associations between paternal factors (age, semen parameters, body mass index, sperm DNA fragmentation index (DFI), and leukocyte count), embryonic ploidy, and the clinical implantation potential of euploid embryos.

STRUCTURE-BASED DRUG DESIGN FOR PARKINSON'S DISEASE: MOLECULAR DOCKING ANALYSIS OF NOVEL COMPOUNDS

Parkinson's disease is a progressive neurodegenerative condition characterized by dopaminergic neuron destruction and misfolded proteins. Current treatments focus on motor symptoms, but do not target neuronal degeneration. Recent studies suggest a connection between lipid metabol...