Research works

Carboplatin/Paclitaxel can be an effective alternative for cisplatin-ineligible patients with locally advanced HNSCC

Abstract Background Despite considerable therapeutic advances, a significant evidence gap remains regarding optimal treatment strategies for cisplatin-unfit patients and whether carboplatin/paclitaxel represents a valid therapeutic alternative. This study investigates the treatme...

Improving emotion regulation and well-being through immersive interaction with chatbots among working adults in Taiwan

This study presents a novel, dual-method validation of how AI chatbot interaction enhances well-being, integrating Flow Theory and Emotion Regulation (Cognitive Reappraisal). Using data from 122 professionals, we combined PLS-SEM to confirm the theoretical paths and an Artificial...

Skeletal Muscle Dysfunction and Exercise Intolerance in COPD and Idiopathic Pulmonary Fibrosis: Extracellular Vesicles as Candidate Mediators of a Lung–Muscle Axis

Skeletal muscle dysfunction and exercise intolerance are major extrapulmonary manifestations of chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), yet their severity is not fully predicted by pulmonary impairment. This narrative review examines...

Chrononutrition and Pediatric Metabolic Health: An Integrative Review of Circadian Biology and Early-Day Metabolic Regulation

Childhood obesity remains one of the most important public health challenges worldwide, resulting from the complex interaction of biological, behavioral, environmental, and socioeconomic factors. Although substantial advances have been achieved in nutritional science, increasing...

Fertility incentives in Canada: Period and cohort perspectives

Abstract We study the fertility effects of the 1997 Quebec Family Policy using two complementary approaches: (i) a period‐based repeated cross‐sectional analysis that examines the impact on period fertility (i.e., fertility rates in a given calendar year, such as births per 1,000...

Enhancing Mn(II)/Mn(IV) Redox Activity and Reducing Polarization of NASICON‐Type Na 3 MnTi(PO 4 ) 3 Through Al‐Doping

ABSTRACT NASICON‐type cathode materials have garnered significant interest for their stable structure and favorable Na + diffusion pathways. However, Na 3 MnTi(PO 4 ) 3 (NMTP) often suffers from substantial voltage hysteresis and limited capacity, primarily attributed to intrinsi...

Source Transparency in Human–AI Communication: Context-Dependent Effects in Emotional Support and Problem Solving

This research examined how source disclosure and task context shape evaluations of generative AI. Across two within-subject experiments, participants evaluated GPT-4o and human responses before and after source disclosure in emotional-support and analytic problem-solving settings...

Short- to mid-term clinical outcomes and return to sport and work after arthroscopic debridement of the extensor carpi radialis brevis in patients with chronic lateral epicondylopathy

BACKGROUND: This study aimed to evaluate the short- to mid-term clinical outcomes following arthroscopic extensor carpi radialis brevis (ECRB) debridement in patients with chronic epicondylopathy humeri radialis (cEHR). We hypothesized that arthroscopic ECRB debridement would res...

Martian‑Regolith Simulant Confined Nanogenerators for Wireless Tactile Sensing for Human‐Machine Interface

Achieving a sustainable energy system for space missions remains challenging due to the continued reliance on Earth-supplied materials. This underscores the importance of in situ resource utilization (ISRU) strategies that convert planetary resources into functional electronic co...

Finite element analysis of a novel repair device for lumbar spondylolysis

Abstract Background This study aimed to compare the biomechanical differences between a novel repair device for lumbar spondylolysis and a nail–hook internal fixation system through three-dimensional finite element analysis. Methods Three-dimensional images of L4–S1 were construc...

The Shift from Cost Cutting to Value Creation: A Paradigm for Integrating Procurement Strategy in Dufil Company, Port Harcourt

Abstract The study examines the shift from cost cutting to value creation through an integrated procurement strategy framework, using Dufil Industries, Port Harcourt as a case context. Procurement strategy was conceptualised through three dimensions, namely strategic sourcing, su...

Polymerization as a structuring strategy for hierarchical order and function

Abstract Polymerization has long been used as a tool for structural fixation: liquid or soft precursors are converted into solids. Recent advances in polymerization-based processing technologies have greatly expanded this role, now allowing complex external architectures to be in...

Good Governance as Responsible Sovereignty: Francis Deng and the Conflict–Development Nexus

The South Sudanese UN official, diplomat, and scholar Francis Deng is widely recognized for his intellectual contributions to the Responsibility to Protect (R2P) principle, most notably through his 1996 coauthored publication, Sovereignty as Responsibility: Conflict Management in...

Does Supply-Chain Digitalization Policy Reshape Supplier Selection? Evidence from China’s Supply Chain Innovation and Application Pilot Program

Although government-directed supply-chain programs increasingly seek to enhance firms’ operational capabilities, their downstream effects on supplier selection—and the firm-level conditions that shape these effects—remain underexplored. Using China’s 2018 Supply Chain Innovation...

Artificial Intelligence in Banking: A Bibliometric Analysis of Research Trends, Intellectual Structure, and Performance-Related Themes

Purpose: This study provides a comprehensive bibliometric analysis of AI integration in banking, mapping research trends, intellectual structures, and performance-related themes. While AI’s growing importance in financial services has attracted scholarly attention, bibliometric s...

Unravelling the genetic structure and genetic relationships of indigenous Greek sheep breeds using SNP markers

Abstract Background Indigenous sheep of Greece represent important genetic resources shaped by long-term adaptation to diverse environments. However, many populations face demographic decline, genetic erosion, and their genomic diversity remains inadequately characterized. This s...

Development of Periodontal Organoid-like Constructs Using Human Periodontal Ligament and Gingival Epithelial Cells: Comparison of Two Assembly Strategies

Periodontal organoid research remains underdeveloped, largely due to the lack of standardized fabrication protocols and multicellular constructs capable of reproducing epithelial–mesenchymal interactions relevant to periodontal biology. In particular, it remains unclear whether d...

Crack mitigating and microstructure engineering through in-process mechanical work in wire directed energy deposited Invar alloy

Abstract Wire-based directed energy deposition (WDED) of Invar alloys is prone to cracking due to high thermal stresses and microstructural anisotropy. In this study, in-process machine hammer peening (MHP) was integrated into WDED to mitigate cracking and control the microstruct...

A New CRT-based Fully Homomorphic Encryption

The idea of computing on encrypted data without decryption dates back to the notion of privacy homomorphisms introduced by Rivest, Adleman, and Dertouzos (1978). Their proposals built using the elegant structure of Chinese Remainder Theorem (CRT), were later shown to be insecure...

Numerical Investigation of Differential Speed Coupling Mechanisms in a 600 L Eccentric Four-Shaft Mixer for High-Viscosity Polyurethane Adhesives

Polyurethane adhesives often suffer from high viscosity, poor flowability, and limited mass transfer efficiency, making it challenging for conventional single-shaft or twin-shaft mixing systems to achieve uniform mixing in large-capacity equipment. This study investigates the dif...