Research works

CODEX RERUM: The Spiral of Resonance. From Nothingness to Life

The Codex Rerum: The Spiral of Resonance (From Nothingness to Life) constitutes the formalization of a Unified Theory of the Metasystem, a closed and coherent logical-epistemological framework extending the principles of computational persistence and harmonic resonance from silic...

PropTech Adoption in Real Estate Management: The Role of AI, Big Data and Digital Platforms in Improving Property Management Performance

Abstract Property management has evolved significantly from traditional manual approaches to technology-driven operations, with Property Technology (PropTech) emerging as a transformative force in the real estate sector. The integration of Artificial Intelligence, Big Data analyt...

The No Paper Paradox: Humour Activation, Container Collapse, and the Completion Signature That Proved the Work Was Finished v2

This release marks Version 2 of the No Paper Paradox record, updating the deposit with both the complete formal manuscript (no_paper_paradox_v2_2.pdf) and an interactive WebGL geometric simulation (no_paper_visualiser.html). The No Paper Paradox documents a canonical structural e...

Failure Modes of Pairwise Affinity Dynamics in Emergent Locality: An Inverse-Stability, Attractor-Selection, and Growth Audit

This exploratory computational study investigates whether low-dimensional relational geometry can be selected, stabilized, and extended by dynamics acting on a symmetric pairwise affinity matrix W. The research is organized as a sequence of falsification tests rather than as a se...

Sequential method for determining the effective dose of remimazolam combined with sufentanil for cervical dilation in hysteroscopic surgery

This study investigated the 50% and 95% effective doses (ED50 and ED95) of remimazolam combined with sufentanil for cervical dilation during hysteroscopic surgery. Prospective single-center dose-finding study using a modified Dixon up-and-down sequential method. Twenty-five patie...

MERLIN SCIENCE — E8 Phi-Vortex Lattice Tuning for Quantum Memory Crystals — E8 Intelligence Research

Here is the narration for the MERLIN SCIENCE video. The finding in one clean sentence: By nesting Fibonacci-scaled E8 root vectors at 132 hertz and its subharmonics, we have identified stable quantum memory crystals that store information through phi-vortex lattices. Let me give...

Computational design and population-level evaluation of a multi-epitope Andes virus vaccine candidate

Andes virus (ANDV) causes hantavirus cardiopulmonary syndrome and remains an important target for vaccine development. This study presents the computational design and evaluation of an in-silico multi-epitope ANDV vaccine candidate. The analysis integrates class-I and class-II pe...

Perspectives on Meditation-based Preparation for Psychedelic Experiences: Insights from Practitioners with Combined Meditation and Psychedelic Experience

Abstract Objectives Emerging research suggests that meditation may support more beneficial psychedelic experiences while reducing the likelihood of lasting negative effects, yet its specific preparatory benefits remain underexplored. This study aimed to investigate the perceived...

Redefinition Capitalism: A Capital Allocation and Macroeconomic Theory of Future Value Creation in the Age of AI

This paper develops Redefinition Capitalism (RCap), a capital-allocation and macroeconomic theory for future value creation in the age of AI. Rather than assuming that capital markets systematically undervalue the long term, it argues that markets already price distant cash flows...

Configuration-Space Topology and the Distinction Calculus: The Exchange Scalar, Its +/-1 Shadow, and a Pre-Registered Derivation Program

Configuration-space topology (CST) derives exchange statistics from the fundamental group of the configuration space of indistinguishable particles: the symmetric group S_N in d>=3 (only boson +1 and fermion -1 exchange phases) and the braid group B_N in d=2 (anyons). This paper...

Why Agents Need a Passport: .fafa — Portable Identity for the Agentic Era

This paper specifies .fafa (application/vnd.fafa+yaml), the IANA-registered media type for declarative agent identity: a portable passport for who an agent is, what it may do, where it is reached, and what it must never do. It complements Agent Cards, Model Context Protocol serve...

Multi-Target Analysis of Xanthone Derivatives as Potential Anti-Trypanosoma cruzi Agents: An Integrated Computational Screening

Chagas disease, caused by the parasite Trypanosoma cruzi , affects approximately 8 million people worldwide. The search for new therapeutic candidates is intensified by the limited efficacy and severe adverse effects of current treatments, such as benznidazole and nifurtimox. In...

RLMT: A Representation-Theoretic Origin for the Mode Amplitude Coefficients, and a Negative Result for Tensor-Sector Coupling

This paper reports two follow-up investigations to the parent RLMT paper. First, we show that the mode amplitude coefficients C1,C2,C3 are fixed up to a single overall scale by identifying the N=3 tension modes with the spin‑1 irreducible representation of SU(2), predicting C1=C2...

Application of remote sensing and geospatial techniques for forest fire monitoring and air quality impact assessment

Wildfires are among the most significant environmental disturbances worldwide, with substantial impacts on ecosystems and air quality. Remote sensing techniques have advanced considerably on detection, characterization, and monitoring of wildfire and their atmospheric effects. Th...

Standing Eligibility versus Runtime Authorization: A Definitional Distinction for AI Governance

Standing Eligibility versus Runtime Authorization distinguishes two governance instruments that are frequently collapsed in AI governance discussions. A standing-status determination takes a certified referent as its object, produces a status, and has continuing temporal effect....

A retrospective comparative study of chronic subdural hematoma in patients with or without decreased level of consciousness

Abstract Background In this retrospective cross-sectional study, we aimed to investigate the effects of preoperative decreased level of consciousness (DOC) on 6-month outcome and the risk factors that compromised the consciousness at admission in patients with chronic subdural he...

Seed-Triggered Onset of Neoclassical Tearing Modes: A Minimal Bifurcation Model and an Open Empirical Test

Neoclassical tearing modes (NTMs) are a principal performance limit in tokamak plasmas: magnetic islands sustained by a helically perturbed bootstrap current, linearly stable yet nonlinearly unstable, and generally requiring a finite "seed" perturbation to trigger sustained growt...

Reading More, Finding Less: A Pre-Registered Anatomy of Mis-Routing in Curated Agent Retrieval

This paper measures how well a curated index works when it is an AI agent's only retrieval mechanism. Agent systems commonly provide curated summaries and index files, a pattern known as progressive disclosure, on the assumption that they help the agent reach the correct content...

Electron-irradiated superabsorbent polymers enhance soil water retention, ion homeostasis, and yield resilience of wheat across a salinity gradient

Soil salinity restricts wheat productivity by reducing water availability, disrupting ion homeostasis, and impairing physiological and reproductive processes. Superabsorbent polymers can improve soil water retention, but the agronomic value of electron-irradiated SAPs relative to...

Therapeutic Reversalof PH-HFpEF via Lung SpheroidCell Exosomes

Abstract Pulmonary hypertension–associated heart failure with preserved ejection fraction (PH-HFpEF) is a prevalent and lethal cardiopulmonary syndrome without effective disease-modifying therapy. We investigated the therapeutic potential of lung spheroid cell–derived exosomes (L...