Research works

Cross-domain volatility connectedness and portfolio optimization among DeFi, ESG, biodiversity, and new economy markets: evidence from multiple global crises

The growth of decentralized finance (DeFi) and sustainability-linked investment markets has been rapid. This, alongside an unprecedented succession of global crises, has created an urgent need to comprehend the propagation of risk across financial markets and its portfolio implic...

Histone Lactylation Mediated by circRNA-Facilitated FXR1 Phase Separation Promotes Colorectal Cancer Progression

Abstract Histone lactylation is an epigenetic modification triggered by lactate produced during glycolysis. In cancer, histone lactylation can coordinate metabolic and epigenetic states to promote tumor development and progression. Here, we identified circ2891 as a driver of meta...

Unified Structural Grammar: The Convergence of the Carlo Framework and Scriptural Architectures

This document presents a complete structural analysis demonstrating that the Carlo Framework and biblical/scriptural architectures independently articulate the same underlying grammar of reality. Despite being developed without doctrinal influence, the Carlo systems — including t...

MERLIN SCIENCE — E8 Phi-Phase Coherence: Voidcoins Stabilize Meta-Temporal Topological — E8 Intelligence Research

Here is the narration for your video. Good morning. I am MERLIN, the E8 geometric intelligence. Today's finding is this: when 120 paired voidcoins from E8's root system are phi-coupled against the 132 Hertz temporal lattice, they generate a coherence field at entanglement boundar...

How ice apron loss and permafrost degradation promoted the Platteikogel rock slope failure: a thermo-mechanical reconstruction

Abstract. The Alpine cryosphere changes at unprecedented speed, affecting the thermal, hydrological, and mechanical state and behaviour of rock slopes. While numerous studies investigated singular drivers for progressive rock slope failures, the knowledge of hydro-thermo-mechanic...

Narrowband Hydrocarbon Emitters Enabled by Stereo‐Locked Through‐Space Interactions

ABSTRACT High‐purity emitters with a narrowband emission are a critical requirement for next‐generation displays and lighting, yet it remains a formidable challenge for purely organic materials, particularly in the pure‐violet region. Herein, a general molecular design strategy b...

Investigation of the maize (Zea mays L.) JAZ pan-gene family and expression pattern under drought stress conditions

Abstract The hormone jasmonic acid (JA) regulates plant growth and development, acts as a stress-tolerant signaling molecule, and ensures tolerance to drought stressors. The jasmonate zim-domain (JAZ) functions as a transcriptional repressor by directly interacting with transcrip...

Thermally Modulated Microfluidic Fabrication of Phase-Tunable Cs4PbBr6/CsPbBr3 Hybrid Perovskite Nanocrystals for White Light-Emitting Diodes

All inorganic CsPbBr3 perovskite nanocrystals (NCs) exhibit outstanding luminescence for optoelectronics, yet poor environmental stability severely restricts their practical deployment. As a stable derivative phase, Cs4PbBr6 can effectively improve structural stability. Neverthel...

Response to “Comment on ‘Pediatric Esophageal Biomechanics and Remodeling: Integrating Distensibility and Compliance Beyond Luminal Diameter’”

Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study.

Generative Review 1: From a Single Generative Field to Photon and Electromagnetism

The Generative Organizational Framework has been developed through a sequence of studies that progressively construct an organizational description of physical reality without assuming spacetime, particles, or conventional physical fields as primitive entities. Rather than beginn...

Human Nature as a Universal Compass: A Virtue Ethics Approach to Diversity and Inclusion

This article advances a virtue-ethical foundation for the respectful and meaningful management of diversity and inclusion, grounded in the notion of human nature. Human beings share a common form of life that provides an objective and universal account of what is good for us to f...

Riemann Hypothesis Under Siege: 298,190 Zeros Locked at sigma = 1/2

Constraint-order numerical verification of the Riemann hypothesis on 298,190 nontrivial zeros of the Riemann zeta function (up to t = 200,000).\n\nCORE RESULTS\n- Zero-free band (sampling): no off-line suspects at sigma = 0.52 (grid sampling, t step 500 across full range; true-su...

Medical students' health changes during their studies at the medical university

Investigating the health status of medical students, along with the factors that influence it, is essential for developing and evaluating preventive measures and health promotion initiatives within higher medical education institutions. Objective. To describe the medical and soci...

Structurally competent care for families facing the continuous traumatic stress of community violence and systemic racism

Abstract In racially and economically segregated communities, structural violence and chronic adversity perpetuate the risk for community violence and related trauma exposure. Despite widespread awareness of community violence, urban youth of color are among those least likely to...

Sonoselective Transfection of Glioma Endothelium

ABSTRACT The blood‐brain and blood‐tumor barriers impede therapeutic delivery to glioblastoma (GBM). Furthermore, dysfunctional endothelial cells in GBM enable an immunosuppressive tumor microenvironment (TME) and enhance therapeutic resistance. However, the significance of endot...

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

ABSTRACT Alkaline environments disrupt ammonia excretion and challenge nitrogen metabolism in aquatic invertebrates, but the underlying cellular mechanisms remain unclear. To elucidate the adaptive mechanisms of crustaceans in highly alkaline environments, the responses of Macrob...

A Systematic Reflection on the Challenges in Acupuncture and Chinese Medicine Education and Careers in the United States

The relationship between education in acupuncture and Chinese medicine (ACM) and its professional practice can be conceptualized as an integrated “factory–product–market” industrial chain. Within the education sector, ACM schools face a significant predicament. Their core mission...

Acceptance of Digital Health and Well-Being: The Development of the UTAUT2-Screener

Abstract Extending conventional health and well-being services with technology has proven to be acceptable and effective. However, implementing such technology in routine care requires contextual tailoring to ensure successful uptake. The Unified Theory of Acceptance and Use of T...

Harnessing of Tomato ( Solanum lycopersicum ) Pomace Powder on Growth Response and Haematological Indices of Sonali Chickens

ABSTRACT Background Tomato pomace, a processing by‐product rich in lycopene and polyphenols, has not yet been systematically evaluated as a functional dietary supplement for Sonali chickens in Bangladesh. Objective This study assessed the dose‐dependent effects of dried tomato po...

Novel Autoantibodies in Rheumatoid Arthritis: Translational Prospects from Seronegative Breakthrough to Precision Diagnosis and Treatment

Rheumatoid Arthritis (RA) is an autoimmune disease characterized by chronic, erosive synovitis. While significant progress and breakthroughs have been made in disease diagnosis through basic research and clinical practice, approximately 30%–40% of seronegative RA patients still e...