Research works

The cup-on-cup technique for managing massive acetabular defects in revision total hip arthroplasty: a systematic review

Severe acetabular bone loss, particularly Paprosky types IIIA and IIIB, remains a major challenge in revision total hip arthroplasty (rTHA). The “cup-on-cup” or “double-cup” construct has been introduced as a salvage technique to improve fixation and restore hip biomechanics. The...

Toward a Metafunctional Theory of Perception: Recursive Triadic Architecture, Neural Metabinding, and Perceptual Worldhood

Perception remains conceptually elusive despite advances in predictive processing, multisensory integration, and large-scale network dynamics. This article develops the Metafunctional Theory of Perception (MTP), an integrative, neurophenomenologically constrained framework within...

Airway administered artificial mitochondria-enriched nanovesicles for efficient and selective mitochondria transfer to intervene in pulmonary fibrosis

Mitochondrial transplantation is a promising therapeutic approach involving the transfer of exogenous mitochondria into diseased cells to restore impaired mitochondrial homeostasis. However, its clinical translation is severely limited by the lack of efficient methods for precise...

Prevention of new-onset chronic kidney disease with renin–angiotensin system blockers in type 2 diabetes with preserved kidney function

Renin–angiotensin system (RAS) blockers, including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), are known to slow chronic kidney disease (CKD) progression in patients with established renal impairment. However, whether RAS blockade ca...

Molecular and immunological insights into honey as a complementary approach in hepatocellular carcinoma: a systematic review

Abstract Hepatocellular carcinoma (HCC) is a rising worldwide health problem characterized by high mortality. The presence of early asymptomatic phases, the delay in diagnosis, and limited options for curative surgical interventions all enhanced its severity. Various contributing...

Riemann Hypothesis: 298,190 Zeros Verified, Sampled to 200 Trillion — Pure Python, One Command

Numerical verification of the Riemann hypothesis: complete verification of the zero list\n(t <= 200,000, density-matched to the von Mangoldt formula), extended and confirmed at the\nbillion scale (t ~ 10^8) by truncation sampling. Every listed zero carries two independent\nexhaus...

Companionship and Control: Experiencing ChatGPT as Writer-Identity Work in L2 Academic Writing

Abstract The rise of generative artificial intelligence (AI) is reshaping the landscape of academic writing. Existing research has largely emphasized functional aspects of tools such as ChatGPT (e.g., efficiency, accuracy, and plagiarism) while often overlooking how writers actua...

Biophysical reprogramming of immunosuppressive neutrophils by cold atmospheric plasma reinvigorates antitumor immunity

Neutrophils are increasingly recognized as key orchestrators of the immunosuppressive tumor microenvironment, yet their intrinsic plasticity, short lifespan and resistance to genetic manipulation have impeded therapeutic targeting. Here, we report a non-pharmacological, biophysic...

Macroeconomic dynamics and financial performance of mutual fund companies: Evidence for rational investment decision

Mutual funds are vulnerable to market risk. Maintaining an investment portfolio is challenging under such conditions. This study aims to investigate the macroeconomic variables and return on asset (ROA) of mutual fund firms to examine the impact of these factors on the firm's bas...

Groundwater Variability Is Strongly Linked to Soil Temperature Across Global Aquifers

Abstract Groundwater plays a critical role in land‐atmosphere interactions by regulating soil moisture and surface energy fluxes, yet its contribution to land‐surface processes and heat extremes remains poorly quantified globally. Here, we combine observation‐based aquifer record...

Boundary-Generated Overlap Measures under Principal Jacobi Extensions

Let $H_n$ be a finite real symmetric Jacobi matrix, let $H_nu=\lambda u$, and embed $u$ by zeros into a larger principal Jacobi extension $\widehat H$. The squared overlaps of the embedded vector with the eigenvectors of $\widehat H$ define a probability measure $\nu$ on shifted...

A Clustering-Based Multi-Task Balancing Method for Depot Optimization in Single-Depot Multiple Traveling Salesman Problems

In the single-depot multi-traveling salesman problem, traditional depot location methods often overlook task balance among traveling salesmen, leading to excessive load on certain units and compromising overall operational efficiency. To address this issue, this paper proposes an...

Playing the strong game: Investigating pre-season strength adaptations in elite female rugby league athletes

Maximising strength and power during pre-season is essential for performance success and injury mitigation in rugby league athletes. The typical pre-season strength and power adaptations in elite national level female rugby league athletes are currently unknown. An observational...

Using insertable cardiac monitors to test determinants of heart rate and activity in captive baboons

Insertable cardiac monitors (ICMs) provide fine-grained, continuous data on cardiac activity. These data have great potential to reveal individual physiology, energetics, and stress responses, with implications for animal health, cognition, welfare, and conservation. However, the...

long covid and subjective wellbeing among U.S. working-age adults

Long COVID symptoms can persist for months or years, impeding daily functioning, employment, and social relationships. While prior research links long COVID to adverse clinical mental health outcomes, less attention has been paid to broader subjective wellbeing—including life sat...

Geotechnical Characterization of Carbide Lime

Carbide lime is a calcium hydroxide-rich by-product generated during the production of acetylene gas from the reaction of calcium carbide with water. This study characterized carbide lime to evaluate its suitability for geotechnical and engineering applications through chemical a...

Ascetics, slaves, and necessity in Late Antiquity: renouncing all wealth, but for a single slave

Slave owners in Late Antiquity viewed the possession of at least one slave to be a necessity and a defining mark that distinguished the dignified social classes from the poor. Ascetics who shared this perspective faced a choice when renouncing all worldly possessions in pursuit o...

EuroMillions Breakthrough Mining — 1479 Sources, 10394 Leads Extracted — E8 Intelligence Research

Mined 1479 lottery+quantum breakthroughs. Extracted 10394 leads across 13 categories. 8487 high-value leads found. Categories: {"CORRIDOR": 855, "FORMULA": 707, "GEOMETRIC": 677, "FORWARD_ATTEMPT": 886, "QUANTUM": 1099, "TIMING": 179, "CELESTIAL": 795, "GEMATRIA": 840, "CONSTANT"...

Durable Interphase Engineering on SiO x Anodes Through Interfacial‐Enrichment‐Facilitated Polymerization

ABSTRACT Constructing a robust solid electrolyte interphase (SEI) is a proven strategy to enhance the performance of Si‐based anodes by accommodating severe volume swings and suppressing interfacial side reactions. However, existing strategies that rely solely on either chemical...

Human metapneumovirus outbreaks in healthcare facilities: a review of the literature

Human metapneumovirus (hMPV) is a significant cause of acute lower respiratory infections (ALRIs), and outbreaks have occurred in healthcare settings. We reviewed 22 articles presenting original data on hMPV outbreaks in healthcare facilities published in PubMed until 1 October 2...