Research works

Telesupervision of allied health students during work-integrated learning: a scoping review of the international evidence-base and its representation in localised professional guidelines

Abstract Background Work-integrated learning (WIL) plays a critical role in the experiential construction and assessment of allied health students’ professional capabilities, forming a core component of allied health education programs. Innovation in work-integrated learning has...

Two major floods affect fish, invertebrates and marine habitats within a temperate estuary

Context Severe flooding can cause physiological stress and mortality for marine organisms within estuaries through reduced salinity, increased turbidity and sedimentation, and the delivery of nutrients, organic matter and contaminants. Aims The Port Stephens estuary in Australia...

What a slice-level benchmark certifies without the pixels: a label-file audit of seven public benchmarks, and a protocol-frozen random-sample screen of how often the check is reported

Background. Volumetric images are often labelled and scored one slice at a time. Shortcut learning, acquisition confounding and the inflation caused by slice-level splits are documented, and a pixel-free positional baseline is itself prior art; what is unmeasured is how much of a...

Outcomes following major dysvascular lower limb amputation: an updated systematic review

Abstract Background Adults with major lower limb amputation (LLA) due to dysvascular etiology often experience diverse health outcomes. However, the absence of standardized outcome reporting limits the ability to synthesize evidence, evaluate care models, and develop consistent c...

Wanted? The Elusiveness of (Post-)Growth in Anthropocene Research

Abstract There is now wide agreement that the Earth has entered a new geological epoch as a result of human activities, which is often encapsulated in the concept of the “Anthropocene.” Meanwhile, there remains considerable debate about the impact of economic growth on planetary...

The use of machine learning models for subdural hematoma detection: a single-arm meta-analysis

Abstract Manual evaluation of non-contrast CT scans (NCTS) for detecting subdural hematoma (SDH) is time consuming, potentially inaccurate, and subjective to the expert analyzing them. In recent years, two deep learning (DL) algorithms have been popularly studied in this respect,...

Recovery-phase contamination of the resting baseline window in block-design fNIRS: a computable criterion and a diagnostic protocol

In block-design functional near-infrared spectroscopy (fNIRS), the resting baseline window is placed by convention rather than by derivation. We show that the recovery phase of the preceding hemodynamic response and anticipatory recruitment for the upcoming task act on that windo...

Unraveling Immune Dysregulation in ZNFX1 Deficiency: From Interferonopathies to Macrophage Activation Syndrome

Abstract Purpose ZNFX1 interferes with early viral replication after exposure to type I interferon, and interacts with mitochondrial antiviral sensors (MAVS) leading to a balanced expression of interferon-stimulated genes (ISGs). ZNFX1 deficiency mimics systemic autoinflammatory...

Performance Analysis of Dielectric-Modulated C-ShapedPocket Dual-Gate Metal-Stacked Oxide-Sandwiched Drain TFET-Based Biosensor

Abstract The article examines the performance of a C-shaped dual-gate metal-stacked oxide-sandwiched drain TFET (CSP-DGM-SO-SD TFET) designed for label-free biosensing applications. Key design considerations such as dual nanocavity placement, a C-shaped pocket region, a sandwiche...

“Am I doing everything right enough?”: a mixed methods evaluation of the early post-bariatric surgery period

Abstract Background The post-bariatric surgery period is a multidimensional experience encompassing individuals’ physical, psychological, and social adjustment processes. During this period, personality functioning and emotion regulation abilities may significantly influence post...

Multi-scale characterization of karst media, negative-pressure suffusion mechanism and collapse risk assessment for urban metro engineering: A case study of Guiyang metro line 3, China

Abstract Multi-scale characterization of karst media is a fundamental prerequisite for accurate stability evaluation and collapse risk assessment in karst terrains, especially for the safety control of urban metro engineering. Taking the Huaxi South Parking Lot of Guiyang metro l...

MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA

Abstract The oncoprotein MDM2 is widely recognized as the principal negative regulator of p53, thereby controlling the expression of numerous RNA polymerase II (Pol II)-dependent genes involved in cell cycle arrest and apoptosis. Beyond this canonical role, MDM2 also engages in t...

Patients’ perceptions on HIV testing and starting antiretroviral therapy during implementation of universal test and treat

Abstract Introduction Universal Test and Treat (UTT) was introduced to South Africa in 2016 as an HIV prevention and treatment strategy. In this study we aimed to assess the individual perspectives of people living with HIV (PLWH) on starting antiretroviral therapy (ART) during t...

Artificial intelligence-supported segmentation of cardiac anatomy in open-heart surgery videos

Abstract Accurate identification of anatomical structures is essential for safe congenital cardiac surgery and for the development of assistive robotic systems. However, scalable annotation of open-heart surgical video remains a major challenge due to dynamic tissue motion, occlu...

Concurrence in Neutron–Proton Scattering for Polarization-Induced Mixed States

We investigate spin entanglement generated in neutron–proton scattering by evaluating the concurrence from the scattered two-nucleon density matrix. While previous studies mainly discussed pure initial spin states, the present work extends the analysis to polarization-induced mix...

One Core to Root them All: A Core Bacterial Community in Closely Related but Geographically Distant Mammillaria Species from Contrasting Environments

Abstract Understanding the core microbiome has potential applications on biomonitoring and conservation. We explore whether closely related xerophytes from the M ammillaria h aageana s pecies c omplex (MHSC), a recently diverged group (ca. 2 mya) that occupy geographically distan...

Conditional Structural Classification of the GP Network Within Field-Network Theory Application Note to the Mathematical Research Programme

Description This application note presents a conditional structural classification of the Growth Platform (GP) network within the framework of Field-Network Theory (FNT). It does not attempt to prove the engineering performance or empirical effectiveness of the GP network. Instea...

Immune response to DNA and RNA: structural insights, molecular mechanisms, and therapeutic targeting

Abstract The recognition of mislocalized DNA and RNA by cGAS–STING, RIG-I/MDA5, the OAS–RNase L axis, and endosomal TLR3/7/8 has emerged as a unifying paradigm linking cancer, autoinflammation, and antiviral immunity. Counterbalancing these sensors is a structurally heterogeneous...

Hydrogen 1s Orbital from Stochastic Collapse Testing the Quantum Measurement Problem via the Fine-Structure Constant

We test a recently proposed algebraic resolution of the quantum measurement problem by deriving the fine-structure constant from the same dissipative collapse dynamics, and by verifying that the resulting stochastic collapse reproduces the Schrödinger distribution for the hydroge...

Predominant NR1-positive puncta with limited PSD95 colocalization and close GluA2–EAAT2 apposition in the preBötzinger complex

Abstract The preBötzinger complex (preBötC) is a medullary network that generates the inspiratory phase of respiratory rhythm in mammals and depends critically on glutamatergic transmission. To characterize the anatomical organization of excitatory signaling elements within this...