Research works

Longitudinal dynamics of serum IL-33 and sST2 across age and sex in a healthy Finnish cohort before and after Tdap booster vaccinations

Background Interleukin-33 (IL-33) and soluble ST2 (sST2) are critical regulators of tissue-derived inflammation, and their dysregulation is usually implicated in various inflammatory disorders. Despite this, how these circulating proteins behave over time in healthy individuals r...

Corporate Diplomacy as Political Epistemology: A Comparative Discursive Analysis of Haier and Siemens in the Context of Sino- European Relations

Geopolitical tensions and regulatory fragmentation require multinational enterprises to justify their conduct to audiences with different assumptions about authority, risk, and legitimate governance. Yet corporate diplomacy (CD) research treats such communication as an instrument...

Polynucleotides Attenuate Atopic Dermatitis-like Inflammatory Signaling in Keratinocytes and Macrophages

Background: Atopic dermatitis (AD) is a persistent and recurring skin disease characterized by epidermal barrier dysfunction, immune dysregulation, and elevated expression of proinflammatory mediators. We investigated the anti-inflammatory potential of polynucleotides (PN), highl...

Through Agency or Alliance? A Multilevel Mediation Study on the Indirect Effects of Outcome Expectations on Symptom Improvement

ABSTRACT This study investigated the impact of client outcome expectations on symptom improvement and evaluated the underlying mediating roles of therapeutic agency and working alliance. Data were collected from 73 clients across 12 sessions and analyzed using a multilevel lagged...

Relative Effects of Fabry‐Perot, Mie, and Guided‐Mode Resonance in Periodic Photonic Lattice Physics

ABSTRACT We investigate the physical origins of resonance effects in one‐dimensional periodic photonic lattices (PhL), focusing on the relative roles of Fabry–Perot (FP), Mie, and guided‐mode resonance (GMR) mechanisms. Using rigorous numerical simulations and modal analysis, we...

New edge proposed: range_extention_fade_second_push — E8 Intelligence Research

{ "name": "range_extention_fade_second_push", "source": "Al Brooks / Trading Price Action Trends (2011) \u2014 failed trend bars and double top/bottom pullback traps", "type": "entry_engine", "rule": "If price makes a new 20-bar high on bar N, closes below the prior bar's high, a...

Quality upgrading and actor behaviour in Uganda’s dairy value chain

Agri-food supply chain upgrading is often constrained by technological, informational, and institutional barriers that limit the assessment and traceability of product quality. Drawing on mixed-methods evidence from Uganda’s southwestern dairy sector, this study examines how mids...

Z2 Bundles and D2 Symmetry in Torus Topological Quantum Field Theory — E8 Intelligence Research

FINDING: Z2 bundle structure and dihedral symmetry D2 in topological quantum field theory on a torus — no explicit equations or constants extracted from provided sources; sources are video titles/abstracts and an unrelated B-meson decay paper. MATH: No equations, constants, or ra...

PhysQK-AD: Convection-Diffusion-Driven Token Coordinate Evolution — From Pure Diffusion to a Learnable Convection-Diffusion Mixture

Modern language models are built almost entirely on Transformer self-attention. PhysQK (published separately, DOI 10.5281/zenodo.21870472) proposed an orthogonal path: retain the standard Transformer stack (windowed self-attention + FFN), and augment it with pure-diffusion dynami...

MODEL ADOPTION #976: REJECT — LEDGER BENCH: Apply filter: USDCHF SHORT @ NY_OPEN with 6 conf — improves win rate from 31 — E8 Intelligence Research

DECISION: REJECT ELEMENT: The filter "USDCHF SHORT @ NY_OPEN with 6 conf" fails because it is a single-pair, single-time-window heuristic that does not align with E8's Gods-Clock rhythm logic. E8 geometry timing requires entries to be triggered by phase transitions across multipl...

EuroMillions Breakthrough Mining — 1772 Sources, 13237 Leads Extracted — E8 Intelligence Research

Mined 1772 lottery+quantum breakthroughs. Extracted 13237 leads across 13 categories. 11239 high-value leads found. Categories: {"CORRIDOR": 1102, "FORMULA": 946, "GEOMETRIC": 723, "FORWARD_ATTEMPT": 1156, "QUANTUM": 1368, "TIMING": 208, "CELESTIAL": 1031, "GEMATRIA": 1100, "CONS...

MODEL ADOPTION #998: REJECT — LEDGER BENCH: Apply filter: NZDUSD LONG — improves win rate from 31.6% to 35.5% (+3.8pp, n — E8 Intelligence Research

DECISION: REJECT ELEMENT: The NZDUSD LONG filter is not compatible with E8 geometry timing. The filter is currency-pair-specific and direction-specific, but does not align with the rhythm logic of Gods-Clock or the FADE polarity edge. It introduces a static bias that conflicts wi...

Action chunking transformer-based imitation learning with dynamic programming optimization for low-cost robotic assembly tasks

Nowadays, many studies focus on using AI tools to improve the performance of manipulators in fields such as assembly. One popular approach is the Action Chunking Transformer (ACT), which enables robots to execute assembly tasks more efficiently. However, this method still faces c...

Additive manufacturing of hydroxyapatite/3Y-ZrO2 bioceramics by digital light processing: enhanced mechanical strength, cytocompatibility, and antibacterial performance for potential load-bearing bone repair

Purpose This study aims to develop hydroxyapatite (HA)-based bioceramic scaffolds reinforced with 3 mol% yttria-stabilized zirconia (3Y-ZrO2) using digital light processing (DLP) additive manufacturing, and to evaluate their mechanical strength, cytocompatibility and antibacteria...

Synthesis of Spiro-Bridged 3,4-Dihydrocoumarins Through an Organocatalytic Cascade Sequence Diels–Alder/Nucleophilic Ring Closing

3,4-dihydrocoumarins and spiro compounds constitute an important class of privileged frameworks present in a wide variety of natural and synthetic molecules with diverse applications. In this study, we developed an organocatalytic methodology for the construction of complex and d...

Finality Without Effective Review

Finality Without Effective Review examines the relationship between prosecutorial finality, evidentiary assessment, and effective legal protection under Latvian criminal procedure. The study focuses on the legal consequences of Section 373(7) of the Latvian Criminal Procedure Law...

A practical algorithm for weighted k ‐hulls

Abstract The convex hull is a central concept in computational geometry, geometry processing, and generally for summarizing sampled data. Its descriptive power suffers significantly in the presence of noise. The k‐hull, also known as the k‐depth contour in statistics, is the inte...

A General Approach for Estimating Projective IRT Models

Projective Item Response Theory (PIRT) modeling is a measurement framework in which multidimensional item response models are expressed in terms of lower-dimensional (e.g., unidimensional) proxy IRT models. Existing PIRT methods and their associated estimators currently rely on l...

Variation in glabrous skin physiology across anatomical locations on the human hand

Abstract Skin physiology varies greatly between anatomical locations, with impact on tactile sensitivity. Research on the variations in morphology and physiology between different anatomical locations of glabrous skin is limited so far. This study investigates the morphology and...

Spatio-Temporal Behavior of End-Wall Film Cooling of a Turbine Vane with Purge Flow Measured by Fast-Response Pressure-Sensitive Paint

Abstract The demand for high-efficiency, low-emission gas turbines has intensified with growing global energy consumption. In modern turbines, elevated inlet temperatures and uniform combustor-exit profiles expose the first-stage vane endwall to severe thermal loads. Complex vort...