Research works

Pulsed Field Versus Cryoballoon Ablation for Atrial Fibrillation: Procedural Outcomes and Hemolysis-Related Laboratory Changes in a Single-Center Pilot Study

Background and Objectives: Pulsed field ablation (PFA) and cryoballoon ablation (CRYO) are established approaches for pulmonary vein isolation in atrial fibrillation (AF). Given emerging concerns regarding hemolysis following PFA, this pilot study aims to directly compare outcome...

Mapping autonomy in mental health care: a scoping review protocol

Autonomy is regarded as a fundamental principle in the global reform of mental health care, as promoted by the Convention on the Rights of Persons with Disabilities (CRPD) and reflected in various international initiatives aimed at eliminating coercive practices and fostering rig...

The locus coeruleus gateway hypothesis: Noradrenergic integrity as a candidate determinant of amyloid-β clearance efficiency in anti-amyloid immunotherapy for Alzheimer's disease

) status, or tau burden-leave largely unexplained. We propose that a systematically unmeasured upstream variable contributes to this variability: the structural integrity of the locus coeruleus (LC), the principal source of brain norepinephrine (NE), framed as a candidate determi...

Undecidability in Computation and Physics: Fundamental Limits from Halting and Incompleteness — E8 Intelligence Research

FINDING: Undecidable problems (halting problem, Gödel incompleteness) impose fundamental limits on computation and physics, revealing that not all physical questions are algorithmically solvable. | MATH: Halting problem: no Turing machine can decide if an arbitrary program halts...

Translating Complexity into Credible Evidence: Quantum Expert Witnesses in Construction Disputes Arena

Abstract In construction disputes, resolution often hinges not only on the strength of legal arguments but also on the persuasive power of numbers, figures that are frequently complex, contested, and highly consequential. Within this landscape, quantum expert witnesses—independen...

When Does an Accounting Inequality Have Teeth? A landing criterion for the maintenance power bound in prebiotic chemistry, with a first empirical execution

Abstract Background. Prebiotic chemistry has long lacked a common ledger. Synthesis experiments either reconstruct reaction pathways or investigate energetic conditions in isolation; over several decades the two have advanced separately, and the two standard strategies, “lower th...

Spatial distribution of short birth intervals and associated factors among reproductive-age women in Somalia, 2020: a spatial and multilevel analysis

Short birth interval (SBI) is a major contributor to maternal and child morbidity and mortality. In Somalia, a nation experiencing high fertility rates alongside protracted conflict and humanitarian crises, evidence on birth spacing patterns is scarce. This study investigates the...

Real-Time Symptom and Wearable Monitoring May Improve Prediction of Postoperative Recovery in Lumbar Spine Surgery Beyond Standard Measures

BACKGROUND AND OBJECTIVES: Accurately identifying candidates likely to benefit from surgery and addressing modifiable preoperative risk factors are central to optimizing outcomes. Current prediction tools often rely on static clinical data and patient-reported measures, which lac...

Diketopyrrolopyrrole‐Based Cation as a Semiconducting Spacer in Layered Perovskite

ABSTRACT Incorporating π‐conjugated organic spacers in layered “2D” perovskites in order to extend solar light harvesting has remained a challenge, as typically‐incorporated spacers (e.g. phenethylammonium, PEA + ) do not absorb deep into the visible spectrum. Here, we introduce...

Hyperacute Cytokine Kinetics and Early Interleukin-10 Elevation as Predictors of Neurological Outcome in Post-Cardiac Arrest Syndrome

Background: Post-cardiac arrest syndrome (PCAS) involves a complex interplay between systemic inflammatory and compensatory anti-inflammatory responses. The hyperacute kinetics of these cytokines and their incremental prognostic value beyond established brain injury biomarkers re...

Could foods from the Mediterranean diet act as a DNA-protective tool against the mutagenic and genotoxic effects of urban fine air particulate matter (PM0.5)? An exploratory investigation on bacteria and human cell lines

Fine particulate matter (PM 0.5 ) is an emerging public health concern due to its ability to penetrate deeply into tissues and induce oxidative stress–mediated damage, contributing to the development of chronic diseases. Despite increasing exposure in urban environments, its biol...

Sleep and Stroop Performance with Adjunctive Melatonin in Pharmacotherapy-stable Pediatric ADHD: A Prospective Open-label Study

Background: Attention-deficit/hyperactivity disorder (ADHD) is frequently comorbid with sleep disturbances; evidence linking melatonin to objective neurocognitive outcomes in this population is lacking. The present study assessed the association of melatonin with parent-reported...

How university drive agribusiness entrepreneurial opportunity exploitation? A knowledge orchestration perspective

Purpose This study aims to explore how university knowledge embedding enables agribusinesses to exploit entrepreneurial opportunities in resource-constrained environments. Specifically, it examines the dynamic transition from passive adaptation to proactive creation in firm-unive...

Monitoring Injected Drug Use in Greece Through Syringe Residue Analysis: A Multicity Study Within the ESCAPE Network

This study presents findings from the European Syringe Collection and Analysis Project Enterprise (ESCAPE) conducted in Greece between 2022 and 2024. Used syringes were collected through harm reduction services and needle distribution and collection programs coordinated by EOPAE...

Study on Walnut Oil–Fructooligosaccharide Emulsions Fabricated by High-Pressure Microfluidization and Their Application in Improving Rice Quality

The present study aimed to optimize the fabrication conditions of walnut oil–fructooligosaccharide emulsion and evaluate its efficacy in improving the quality of cooked rice. Three food-grade emulsifiers, namely sucrose fatty acid ester (SE), polyglycerol fatty acid esters (PGEs)...

Factors for Success and Failure of Allergen Immunotherapy ( AIT ) Trial Design in the Light of Evidence‐Based Medicine: Current Aspects 2026

Allergen immunotherapy (AIT) has been acknowledged as the only disease-modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study res...

Spatio-ecological determinants of Biomphalaria and Bulinus snail intermediate hosts and schistosome-like infections in the Lango subregion, Northern Uganda: a geostatistical approach to guide targeted disease control

Abstract Background Freshwater snails of the genus Biomphalaria transmit Schistosoma mansoni (intestinal schistosomiasis), Bulinus species transmit S. haematobium (urogenital schistosomiasis), and Lymnaea species transmit Fasciola spp. (fascioliasis). These diseases are of major...

Spatiotemporal Evolution and Nonlinear Drivers of Eco-Environmental Quality Under Production–Living–Ecological Space Transition in Northern Xinjiang: An XGBoost–SHAP Analysis

The development of arid-oasis agriculture and territorial spatial restructuring strongly influence regional eco-environmental quality. Clarifying production–living–ecological space (PLES) transitions and the nonlinear mechanisms driving eco-environmental quality is important for...

The Consent to Destroy: Imperial Melancholia and the Hegemony of Fragmentation

Across the world’s most powerful states, millions actively embrace the destruction of the shared reality on which democratic life depends. Democracy does not simply collapse from without; it can be unmade from within through consent. This article introduces hegemonic fragmentatio...

Symmetry Breaking Entropy: Quantum Randomness in Wigner-Eckart Corrections — E8 Intelligence Research

FINDING: Spontaneous symmetry breaking (SSB) in quantum systems is linked to algorithmic randomness and incompressibility, with corrections to Wigner-Eckart relations providing a quantitative measure of symmetry-breaking entropy. | MATH: Wigner-Eckart theorem: ⟨α', j'| T_q^(k) |α...