Research works

History of worsening heart failure and outcomes with vericiguat in ambulatory HFrEF: an exploratory post-hoc analysis of VICTOR

Stefan Störk, Javed Butler, Caroline Morbach, Fabian Kerwagen, Johann Bauersachs, Ephraim B Winzer, Justin Ezekowitz, Carolyn S P Lam, Inga Bayh, Stefan He

Planned Social Media Ban and Depression and Anxiety in Adolescents

This cohort study assesses underlying assumptions pertaining to adolescent mental health in the implementation of the Social Media Minimum Age restrictions in Australia.

The Geometry of Bitcoin: A Tangent-Based Asymptotic Model and Finite-Time Singularity

The traditional Power Law model for Bitcoin is limited; it struggles to simultaneously fit historical data points across different eras without piecewise parameter adjustments. Bitcoin's trajectory is more naturally described as a tangent-based hyper-exponential system, driven by...

Chaos Without Infinity: How Computational Finitism Resolves the Paradox of Deterministic Chaos

Deterministic chaos has long been considered a hallmark of continuous nonlinear systems, characterized by sensitive dependence on initial conditions and positive Lyapunov exponents implying infinite divergence. We challenge this paradigm through the lens of Computational Finitism...

Dried blood spots perform well in the quantification of HBV DNA and detection of HBeAg

Abstract Background Hepatitis B virus (HBV) DNA quantification and hepatitis B e-antigen (HBeAg) detection are recommended in the management of chronic HBV infection. The use of dried blood spots (DBS) collected with fingerstick could improve access to these tests in resource-lim...

Web-Based Risk Communication for Visitors to the Cascadia Coast: A Systematic Review of Official Destination Websites

Destination websites provide information to visitors about local attractions, events, amenities, and businesses. However, it is unclear how much websites for coastal tourism inform tourists about coastal hazards and safety threats they may be exposed to while visiting. Prior rese...

Health Literacy and Interprofessional Education: Contributions of Speech-Language Pathologists

PURPOSE: Health literacy and health literacy gaps add layers of complexity in health care. Speech-language pathologists (SLPs) offer a unique skill in addressing health literacy disparities within health care teams and with patient care provision. This commentary discusses the sy...

EuroMillions Breakthrough Mining — 3003 Sources, 25598 Leads Extracted — E8 Intelligence Research

Mined 3003 lottery+quantum breakthroughs. Extracted 25598 leads across 13 categories. 23298 high-value leads found. Categories: {"CORRIDOR": 2171, "FORMULA": 2005, "GEOMETRIC": 894, "FORWARD_ATTEMPT": 2305, "QUANTUM": 2520, "TIMING": 273, "CELESTIAL": 2091, "GEMATRIA": 2203, "CON...

Phytochemical and Pharmacological Evaluation of Wodyetia Bifurcata Leaf Extracts in High-Fat-Diet-Induced Hypercholesterolemia-Associated Diabetes in Albino Rats

ABSTRACT Background: Hypercholesterolemia and diabetes are interrelated metabolic disorders in which disturbed lipid metabolism, oxidative stress and impaired glucose homeostasis may coexist. This study investigated the phytochemical composition and pharmacological potential of W...

Audience Engagement or Production Scale? Determinants of Film Return on Investment in the Motion Picture Industry

The film industry presents one of the most capital-intensive and financially uncertain environments within cultural markets. While prior research has predominantly measured success through box office revenue, return on investment (ROI) offers a more meaningful lens for producers...

Human centered artificial intelligence for smart city traffic coordination

Abstract Smart city traffic systems increasingly rely on edge intelligence and distributed learning to coordinate vehicles and infrastructure. However, many existing approaches prioritize system-level optimization while overlooking how humans perceive, interpret, and respond to a...

The Infinite Line and the Theater of Possibility: A Non-Reductionist Framework for Environmental Coupling and Multi-Axiomatic Reality

Traditional theoretical physics is dominated by a reductionist obsession with micro-mechanics and the perpetual search for how every physical interaction unfolds. This paper presents an inverted epistemological and ontological framework that shifts the primary focus from mechanic...

The effects of different prone positioning angles on cardiopulmonary function in children after congenital heart disease surgery: a randomized controlled trial

To evaluate the effects of different head-elevated prone positioning angles on oxygenation, respiratory mechanics, hemodynamics, and enteral nutrition tolerance in children after congenital heart disease（CHD）surgery, and to determine the optimal intervention angle. In this rand...

Tissue-specific trace element accumulation, mercury and arsenic speciation in Atlantic walrus (Odobenus rosmarus rosmarus)

Walruses ( Odobenus rosmarus ) are long-lived Arctic marine mammals and play an important ecological and cultural role in northern communities. We quantified and compared concentrations of 34 elements in blubber, liver, and muscle tissues from 97 Atlantic walruses ( Odobenus r. r...

Pneumonitis in Older Patients With Non-squamous Non-small Cell Lung Cancer Treated With Pembrolizumab and Pemetrexed

Background/Aim: Pembrolizumab combined with pemetrexed is efficacious in older patients with metastatic non-squamous non-small cell lung cancer (NSCLC) and a PD-L1 tumor proportion score (TPS) of <50%. However, treatment-related pneumonitis is concerning, and its impact on clinic...

Recent advances in zeolitic imidazolate framework-based materials for ciprofloxacin removal from aqueous environments

CIP is a widely used fluoroquinolone antibiotic that poses increasing environmental and public health concerns due to its persistence and biological activity in aquatic environments. Zeolitic imidazolate frameworks, known for their high surface area, tunable porosity, and versati...

Design and analysis of an X-band low-RCS A-sandwich radome based on double-layer frequency-selective surface for modern defence systems

This article presents the design of an X-band A-sandwich radome based on a double-layer frequency-selective surface (FSS) to reduce the radar cross-section (RCS) of the co-designed antenna. The proposed radome is designed with bandstop FSS elements on the top and bottom surfaces...

Multimethod examination of change in autistic preschoolers' emotion dysregulation in the context of parenting stress intervention

Background Many autistic preschoolers experience heightened emotion dysregulation and rely heavily on parents for co‐regulatory support, which may be compromised by elevated parenting stress. Methods We examined secondary outcomes of a randomized trial (ClinicalTrials.gov – NCT03...

EVALUATION OF CYANIDE CONTENT, MINERAL COMPOSITION, AND SENSORY PROPERTIES OF FOUR GARRI SAMPLES PRODUCED IN ANKPA LOCAL GOVERNMENT AREA, KOGI STATE, NIGERIA

The cyanide content, mineral composition, and sensory properties of four garri samples obtained from different local markets in Ankpa Local Government Area, Kogi State. Cyanide levels were determined using the alkaline picrate method, mineral composition was analyzed through atom...

BEFORE DISPERSION - HEAT ATTRACTS — Thermal Causality Through Simple Experimentation

Three simple probe-array experiments examined the spatial and temporal ordering of temperatureduring bottom heating in soybean oil and water. In soybean oil, the bottom probe responded first. During a later 17 s interval of continuous heating,however, the bottom temperature showe...