Research works

Purpose-built WAAM 316L benchmark walls for thermo-mechanical calibration and strain-based hardness prediction

Wire Arc Additive Manufacturing (WAAM) of 316L generates complex thermal cycles, distortion and work hardening that are difficult to validate in 3D. Hence, in this paper, we design, build and fully characterise two benchmark walls (two-layer and three-layer) expressly for calibra...

Effects of aqueous PM2.5 extract on developmental traits of Aedes aegypti mosquitoes

Abstract Seasonal biomass burning in Southeast Asia generates high concentrations of fine particulate matter (PM₂.₅), which can deposit into small aquatic habitats used by mosquito larvae. This study assessed the effects of PM₂.₅-contaminated water on key life-history traits of A...

Drones providing live video to dispatch centers during time-critical incidents

Abstract Background Early triage of emergency calls at dispatch centres relies mainly on verbal information, which may not reflect the complexity and severity of a situation, limiting dispatchers situational awareness and early decision-making. Real-time live-video could potentia...

Butter-Fat

Volume 34 Number 08 November 1956

Taking Aristotle seriously in liberal democracy

This paper replies to Randall Curren’s review of my book, Against Aristotelian Character Education. I argue that Curren’s response leaves the book’s central dilemma untouched. First, I argue that liberal freedom and equality place demands on compulsory public education that exten...

EuroMillions Breakthrough Mining — 2962 Sources, 25199 Leads Extracted — E8 Intelligence Research

Mined 2962 lottery+quantum breakthroughs. Extracted 25199 leads across 13 categories. 22902 high-value leads found. Categories: {"CORRIDOR": 2138, "FORMULA": 1972, "GEOMETRIC": 885, "FORWARD_ATTEMPT": 2269, "QUANTUM": 2482, "TIMING": 269, "CELESTIAL": 2059, "GEMATRIA": 2167, "CON...

Three-body problems involving the mother, fetus, and microorganisms

Pregnancy is a unique immunological state in which the maternal immune system tolerates a semi-allogeneic fetus. Traditionally, this relationship has been viewed as a dyadic interaction between the mother and the fetoplacental unit. However, accumulating evidence suggests that th...

AI Alignment Progress Report 2025: RLHF Successors and Constitutional AI Evaluation

Research article: AI Alignment Progress Report 2025: RLHF Successors and Constitutional AI Evaluation

Butter-Fat

Volume 26 Number 04 July 1948

Extreme Risk Protection Orders Among Military Service Members and Veterans

Importance Service members and veterans who die by suicide disproportionately use firearms. Extreme risk protection orders (ERPOs) temporarily restrict firearm access for individuals deemed at risk of harming themselves or others. Despite elevated firearm-suicide risk among servi...

Transcriptomic profiling of lineage transformation and actionable therapy opportunities in EGFR-mutant non-small cell lung cancer evolving to small cell lung cancer

Abstract Background Neuroendocrine transformation of epidermal growth factor receptor-mutant lung adenocarcinoma (EGFR m LUAD) represents a significant mechanism underlying acquired resistance to EGFR tyrosine kinase inhibitors (TKIs). This histological transformation lacks effec...

A closed-loop calibrated digital twin for vibration suppression and performance enhancement of the milking robot manipulator

The Automatic Milking System (AMS) has significantly improved dairy farming efficiency. However, residual vibrations generated by the high-speed motion of the milking manipulator continue to pose significant challenges, particularly by compromising positioning accuracy and cup at...

Butter-Fat

Volume 34 Number 06 September 1956

Single bi-functional flexible sensor device for simultaneous pH and oxygen monitoring during pre-transplant normothermic perfusion

Monitoring of organ health and tissue damage through real-time sensing of chemical parameters such as pH and oxygen concentration could provide helpful information in the field of solid organ transplantation. Several sensors have been developed to detect oxygen concentrations and...

Spatial distribution, clustering patterns, and economic burden of comorbidities among hospitalised pulmonary tuberculosis patients in Guangdong province: a spatial epidemiological study based on inpatient big data

Background: Comorbidities may complicate the treatment of pulmonary tuberculosis and exacerbate both the clinical and economic burden. We aimed to examine comorbidity patterns, spatial clustering, and economic burden in hospitalised pulmonary tuberculosis (PTB) patients in Guangd...

Global trends and burden of dental caries in permanent teeth (1990–2021)

This study aims to analyze the incidence, prevalence, and years lost due to disability (YLDs) of permanent dental caries using Global Burden of Disease data, and to investigate its correlation with socioeconomic indicators. Data were obtained from the Global Burden of Disease (GB...

Etelcalcetide Versus Cinacalcet for Secondary Hyperparathyroidism in Hemodialysis Patients: A Multicentre Comparison with 24 Months of Follow-Up

Background/Objectives: Secondary hyperparathyroidism (SHPT) is a prevalent complication of end-stage kidney disease. Although etelcalcetide has demonstrated short-term superiority over cinacalcet in randomized trials, real-world comparative data beyond 12 months remain scarce. Th...

Point-Cloud-Based 3D Inspection and Volume Quantification of Drainage-Pipeline Defects Using WCPC-GAN and Density-Adaptive Alpha Shapes

Closed-circuit television (CCTV)-based inspection provides limited depth information and cannot directly quantify the three-dimensional geometry of drainage-pipeline defects. Moreover, the scarcity of annotated point-cloud data and the topological artifacts produced by convention...

Small extracellular vesicles induced by Angiotensin-(1-7) enhance cardioprotection following myocardial ischemia-reperfusion injury

Although Angiotensin-(1-7) [Ang-(1-7)], a non-classical peptide of the renin-angiotensin system (RAS), is widely recognized for alleviating cardiovascular stress through activation of the Mas receptor. we identified a largely Mas receptor-independent pathway that expands its ther...

A Pre-Registered Configuration Test for the Göbekli Tepe Pillar 43 "Date Stamp"

Two published readings assign the animal carvings of Göbekli Tepe's Pillar 43 to constellations and conclude that the pillar encodes a date connected to the Younger Dryas event. This paper audits the published probability and then runs the spatial test both sides have called for...