Research works

Moving beyond treatment: pulmonary function, autonomous motivation, and physical activity enjoyment in adults with cystic fibrosis

Abstract Background Physical activity (PA) and structured exercise are established cornerstones of cystic fibrosis (CF) management. While CFTR modulators have transformed treatment, the psychological factors affecting sustained PA adherence, particularly motivational regulation a...

Ultrasound-guided assessment for decannulation with critically ill patients: a prospective cohort study

Abstract Identifying a diagnostic method and treatment guidance tool for decannulation that can demonstrate anatomical and physiological effects of long-term artificial-airway (AA) in critically-ill-patients (CIPs). In this prospective study, ultrasound-guided-decannulation (UGD)...

Why Contemporary Meaning Is Gossamer

Why Contemporary Meaning Is Gossamer offers a structural account of how meaning behaves in contemporary cultural environments. The paper distinguishes rich meaning, which is layered, slow, ambiguity‑tolerant, and supported by high relational density, from gossamer meaning, which...

The Hecate: An Integration-Gate Scoring Protocol and a 430-Row Cross-Substrate Census of Consciousness States

This paper defines a named measurement unit, the hecate (Hc), and an integration-gate function ordering biological and artificial states: Hc = K · λ^b · σ(κ(φ − φ0)), with one healthy awake adult (H-89) fixed at 1.000 Hc and no scale factor. The unit is provisional. The gate is f...

Controlling Solid Carbon Formation in Gliding Arc CH4 Plasmas

Abstract Non-oxidative coupling of methane (CH4) in plasma reactors offers a promising route for electrified hydrocarbon production but is hindered by solid carbon formation, reducing efficiency and causing reactor fouling. Here, we systematically investigate solid carbon formati...

PUH Theorem 120 (Restated) — Koide Q = 2/3 Is Parameter-Free: the √2 Is Forced by Z₃ Mode Counting, and the Phase (6π+2)/9 Predicts m_τ = 1776.989 MeV

Photonic Universe Hypothesis (PUH) — Restatement with a Prediction. WHY THIS EXISTS. Theorem 120 is cited across this archive as the origin of its strongest empirical claim — that the Koide ratio Q = 2/3 follows from Z₃ symmetry rather than being a numerical accident. IT HAS EXIS...

Bidirectional migration routes of Chelonia mydas from the northern Great Barrier Reef

Understanding the full migration dynamics of highly migratory marine species is essential for effective conservation and management. In sea turtles, research has largely focused on one-way, post-nesting migrations, leaving key gaps in knowledge regarding return movements and over...

Leveraging the Data to Make Your Case: Demonstrating the Value of Pediatric Hospital Medicine to Hospital Leadership

Effective financial stewardship of any clinical program within an academic medical center or health care organization begins with a clear understanding of how the organization generates revenue and allocates it to programs. While the budget allows leaders to see where their finan...

Coverage-Free Fuzzing: LLM-Guided Refinement of Grammar-Based Test Generators

Property-based testing tools such as Hypothesis can turn a formal grammar into a generator of syntactically valid inputs, but the generator itself is typically static: hand-tuned once and reused unchanged for the rest of a fuzzing campaign. We study whether a large language model...

Review of Hypoxemia Quantification Methods for Assessing the Severity of Obstructive Sleep Apnea

Abstract Purpose of Review Obstructive sleep apnea (OSA) is a common nocturnal breathing disorder characterized by recurrent upper airway obstruction during sleep, leading to sleep fragmentation and intermittent hypoxemia. The apnea-hypopnea index (AHI) is the most widely used cl...

Copenhagen longitudinal study on quality of life in a young adult population with gliomas

Abstract Background Patients diagnosed with glioma in the brain are prone to lowered quality of life (QoL). The risk of neurological symptoms and emotional burden may restrict participation in everyday life.The glioma diagnosis is considered chronic with a limited overall surviva...

Modeling a 5D Hamiltonian conservative hyperchaotic oscillator with complicated dynamics

Abstract Based on the 3D Euler equation, 5D generalized Euler equations are realized by introducing three coupling parameters and combining three subbodies with two same axes, whose Casimir energy and Hamiltonian are both conservative. By violating the Casimir energy conservation...

Integrated Genome Mining and Bioactivity-Guided Isolation of Antimicrobial Peptides from Bacillus amyloliquefaciens BS4

Bacterial resistance remains a critical global health challenge, driving the continuous search for novel antimicrobial agents. Bacillus amyloliquefaciens is a recognized repository of bioactive metabolites; however, its full biosynthetic potential requires integrated genomic and...

Categorical Structures as Generative Geometry: A Unified Model of Duality, Thickness, EM/Kleisli Layers, ∞‑Stratification, and Curvature

This paper presents a generative geometric interpretation of categorical structures, where dualization forms layered depth, monads and comonads create thickness, EM/Kleisli yield four-layer organization, and ∞-categorical stratification and curvature describe higher-order deviati...

Edward Miles Vaughan Williams’ classification of antiarrhythmic drugs: then and now

Abstract This historical review provides a short biographical overview of the British pharmacologist Edward Miles Vaughan Williams (1918–2016) and summarises the experimental findings which form the basis for his original definition of three classes of antiarrhythmic drug (AAD) a...

Guilt, Shame, and Compensatory Claims: An Exploratory Case Study of Petitioning by a Victim of Employment Fraud

In the xinfang—or letters-and-visits—complaint reception work of public-sector companies in China, some petitioning matters involve harms that were not directly caused by the company itself. Nevertheless, because the company either controls, or is imagined by the petitioner to co...

Continuous Mission Intelligence: The Decisive Architecture for Command at Machine Speed

Defense AI has succeeded at four layers and created a fifth problem. Data integration, command and control, fleet-scale coordination and platform autonomy all work, and their success is precisely what makes the missing layer decisive. When every sensor, platform and agent is inte...

Understanding Belonging in Practice Placements – a Scoping Review of Studies Examining Health Professional Student Belonging

Abstract Background: Practice placements are an opportunity for health professional students to apply knowledge and skills in real-world environments. A growing body of evidence links students’ sense of belonging to enhanced learning and motivation in higher education. Given that...

Quaternionic Generative Geometry of Primes: Local–Global Hierarchy and Elliptic Interference

We present a unified framework where quaternionic generative geometry realizes the local layer of the number-theoretic hierarchy. Frobenius angles, SU(2) rotations, and elliptic interference form a prime-density field whose propagation yields a PDE hierarchy linking D-modules and...

A Comparison of Pediatric Hospitalization Data in Cosmos and the Kids’ Inpatient Database

OBJECTIVE: To compare characteristics of pediatric hospitalizations in Epic Cosmos, an electronic health record-based database that aggregates voluntarily submitted data from across the United States, with nationally representative pediatric inpatient data in the Kids' Inpatient...