Research works

Employees at risk within the “absent presence” paradox: a longitudinal comparison from non-smart to smart-working reward system in the Italian private/public sector

Purpose This contribution explores the evolution of employee motivation as a strategic asset in organisations. The objective is to investigate how the value of reward systems (monetary vs non-monetary) is changing in the era of the Smart Working Model (SWM), the paradoxes of the...

Applications of large language models in anxiety and depression patient care: a cross-model comparative analysis of dialogue quality

The disease burden of anxiety and depression is becoming increasingly severe, and the shortage of mental health clinical resources restricts patients’ access to care services. Large language models offer a new pathway for digital psychological care, yet standardized horizontal co...

Existence and Uniqueness for a Class of Quasilinear Elliptic Systems with Kato-Type Lower-Order Terms

We study a quasilinear elliptic system λ u | u | p − 2 − div ( a ( x , ∇ u ) ) + b ( x , u ) = f ( x ) , in a bounded domain Ω ⊂ R l ( l > 2 , 2 ≤ p < l ), with homogeneous Dirichlet boundary conditions. The principal part a depends only on the gradient and satisfies strong monot...

EuroMillions Breakthrough Mining — 3687 Sources, 32424 Leads Extracted — E8 Intelligence Research

Mined 3687 lottery+quantum breakthroughs. Extracted 32424 leads across 13 categories. 29915 high-value leads found. Categories: {"CORRIDOR": 2767, "FORMULA": 2592, "GEOMETRIC": 1000, "FORWARD_ATTEMPT": 2934, "QUANTUM": 3167, "TIMING": 319, "CELESTIAL": 2670, "GEMATRIA": 2818, "CO...

Sodium butyrate rescues long-term neurodevelopmental deficits following perinatal methadone exposure

Abstract Background Prenatal opioid exposure (POE) induces long-term neurodevelopmental, behavioral and cognitive deficits for which no targeted treatments are available. The mechanisms underlying POE deficits are poorly understood, but have been linked to a range of central, per...

Genome‐scale insights into metabolic streamlining and photosynthetic energy balance in the extremophile green alga Picocystis salinarum (Picocystophyceae, Chlorophyta)

Abstract Picocystis salinarum is an early‐diverging chlorophyte and the sole described member of the Picocystophyceae, frequently dominating hypersaline and alkaline lakes despite extreme physicochemical constraints. To elucidate the genomic foundations of its ecological success,...

Informational Monism: Emergent Spacetime, Quantum Complexity, and the Architecture of Conscious Agency

This treatise establishes the foundational architecture of Informational Monism, presenting a systematic, logico-axiomatic ontology that addresses the twin crises of spatial primacy in quantum gravity and epiphenomenalism in the philosophy of mind. Moving beyond materialist reduc...

Self-image, Social Divisions and Social Position of the Khatris in the Punjab

This article traces the history of Khatris as a caste group in the Punjab, where, despite their small numbers, they remained visible through the millennia. The article addresses the issues of their self-image, ritual status, occupations and social divisions. It also throws light...

Does Education Shape the Emotionally Intelligent Technology Leader? Educational Attainment, Emotional Intelligence, and Leadership Styles Among IT Professionals

Purpose - This article examines educational attainment as a demographic dimension of emotional intelligence and leadership among IT professional leaders. Methodology - The dissertation analyzed 185 usable surveys using the MLQ 5X, SSEIT, and demographic controls. Education was re...

Pericyte-derived cancer-associated fibroblasts correlate with poor survival and are enriched after chemoradiotherapy in glioblastoma

The role of cancer-associated fibroblasts (CAFs) in glioblastoma remains unclear, as their existence in the brain tumor microenvironment is still debated, given that the normal brain parenchyma is devoid of fibroblasts. It is unclear whether cells described as CAFs represent a di...

Sexual health as an overlooked dimension of holistic recovery after adult spine surgery: an evidence-informed narrative review

Abstract Background Sexual health is a meaningful but under-recognized dimension of recovery after spine surgery. Pain, neurological impairment, mobility, body image, psychological distress, relationship context, and procedure-specific injury may all affect postoperative sexual w...

Influencing Factors and Mechanism of CO2 Trapping and Storage in Tight Sandstone Reservoirs Based on Fractal Characteristics of Pore Structure

To mitigate global warming induced by excessive carbon dioxide emissions, carbon dioxide displacement technology for carbon utilization and storage has attracted growing attention. In this paper, laboratory displacement experiments combined with Nuclear Magnetic Resonance (NMR),...

Interventions to Reduce Financial Toxicity of Childhood, Adolescent, and Young Adult Cancer Survivors: A Scoping Review

Financial toxicity (FT) worsens health outcomes and quality of life for childhood, adolescent, and young adult (CAYA) cancer survivors. This scoping review examines interventions designed to alleviate FT among CAYA cancer survivors and identifies the levels of influence within th...

A tiered deep learning and symbolic reasoning framework for safe, explainable disease diagnosis

This study introduces a modular, AI-powered disease diagnosis system that combines deep learning, neuro-symbolic reasoning, and structured automation to support early, scalable, and explainable clinical decision-making. Built upon the large-scale DDXPlus dataset, the system proce...

l-rhamnose suppresses triple-negative breast cancer via GSTM5-mediated ferroptosis

Triple-negative breast cancer lacks effective targeted therapies, necessitating novel treatment approaches.To evaluate the antitumor efficacy and molecular mechanisms of l -rhamnose in TNBC. We employed an integrated approach combining in vitro cell-based assays and in vivo xenog...

Seamless Transition Between Continuous and Discontinuous Modes Suitable for Natural-Sampled PWM in Variable-Frequency Two-Level VSI Operations

In high-speed drive applications, including drone propulsion systems and high-speed spindle drives, switching frequency is often limited by thermal constraints or cost considerations when the adoption of wide-bandgap power devices is not economically justified. Under these condit...

Why Metrics Matter in Thyroid Eye Disease

Importance Advances in the understanding of the pathophysiology of thyroid eye disease (TED) provide an opportunity to use novel, targeted therapeutic agents. However, our capacity to assess the efficacy and indications for the new agents is potentially limited by the clinical me...

Bone Grafting Using Manually Contoured Femoral Head and Neck Allograft Successfully Fills Femoral and Tibial Tunnel Osteolytic Defects in 2‐Stage Revision Anterior Cruciate Ligament Reconstruction: A Computed Tomography‐Guided Analysis

PURPOSE: To use computed tomography (CT) to quantify the percent filling of tibial and femoral tunnel osteolytic defects using a manually contoured femoral head and neck allograft prior to definitive revision anterior cruciate ligament reconstruction. METHODS: Patients under 50 y...

Nearly-minimax variance estimation under rough random design

We identify the minimax exponent for constant conditional variance estimation under rough random design. The unknown design density is bounded above and away from zero, with no smoothness assumption, and the conditional error laws may depend on the covariates and have uniformly b...

Excess mortality related to the COVID-19 pandemic by age, sex, and cause of death in the Czech Republic

Abstract Background The aim of the study was to estimate the direct and indirect effects of the COVID-19 pandemic on excess all-cause mortality in the Czech Republic by sex, age group and cause of death. Methods National mortality data for the period 2015–2022 were used. For each...