Research works

Outcomes of a Novel Full-Service, Free Ophthalmology Clinic-Within-A-Clinic: A Four-Year Longitudinal Study.

PURPOSE: We evaluate the Clínica Esperanza Ophthalmology Service, a free service for uninsured patients in southern New England. METHODS: The service operates monthly under a novel clinic-within-a-clinic model, existing as a subsidiary of a local free clinic. A mixed-methods prog...

Evaluation of Emergency Department Visits by Refugee Children in Rhode Island.

Children constitute 40% of the world's refugees and often have complex medical needs. This retrospective chart review examined Emergency Department (ED) utilization by pediatric refugees (aged 0-18) within a state-level healthcare system to understand the healthcare needs of this...

Shotgun Metagenomics Identify Unique Changes of the Intestinal Microbiome in Pediatric Survivors of Acute Lymphoblastic Leukemia.

BACKGROUND: Intestinal microbiota plays an important role in human health and metabolism. Microbial dysbiosis has been observed in various chronic conditions, many of which are late effects of leukemia treatment. We previously observed significant differences in the gut microbiom...

Characteristics and Management of Xylazine-Associated Wounds: A Systematic Review of Published Cases.

BACKGROUND: The rise in xylazine-adulterated fentanyl and heroin has been designated as an emerging public health threat due to a devasting pattern of xylazine- associated wounds associated with its injection. This study was undertaken to systematically characterize patient and w...

A Decade of Pathways to Medicine: Program Evaluation and Lessons Learned in Implementing a Local Health-Professions Outreach Program.

Pathway programs provide structured opportunities for students to explore healthcare careers and develop familiarity with educational pathways into the health professions. Ongoing evaluation of such programs is essential to gauge their success and inform iterative improvement. In...

Acute Interstitial Nephritis after Single Dose of Ketorolac.

Acute interstitial nephritis (AIN) is an immunologically mediated cause of acute kidney injury (AKI), most often drug-induced, with NSAIDs being a leading culprit. We present a 39-year-old woman who developed biopsy- proven AIN following a single intramuscular dose of ketorolac,...

Flumazenil Use in Benzodiazepine-Induced Delirium Reversal.

Delirium is a frequent and serious complication in critically ill patients, associated with increased mortality, prolonged hospitalization, and long-term cognitive impairment. The hypoactive subtype is particularly underrecognized, missed in up to 75% of cases, and carries worse...

FORMULATION AND EVALUATION OF MICROSPHERES OF SODIUM VALPROATE USING EUDRAGIT S100 POLYMER

The present study was aimed to formulate and evaluate microspheres of sodium valproate using Eudragit S100 polymer for controlled drug delivery. Microspheres were prepared using solvent evaporation technique. The prepared microspheres were evaluated for particle size distribution...

FORMULATION AND EVOLUATION OF HYDROGEL FACE MASK FOR COMPLETE REJUVENATION EFFECT, USING CLITORIA TERNATEA

Clitoria ternatea L. (Fabaceae), commonly known as butterfly pea or Aparajita, is a well-known medicinal plant widely distributed in tropical regions. It is rich in bioactive constituents such as flavonoids, anthocyanins, phenolic compounds, and tannins, which exhibit potent anti...

EFFECT OF LASER, ANTIBIOTIC, PHOTOSENSITIZER AND THEIR COMBINATIONS ON THE HEALING RATE OF MICE WOUND INFECTED BY STAPHYLOCOCCUS AUREUS

Background: Most workers in the field of laser stimulation for wound healing have applied wave length that presumably do not produce serious damage to the skin of the host. Laser stimulated several aspects of wound healing involving stimulation of blood clotting, phagocytosis by...

ROLE OF RITUCHARYA (SEASONAL REGIMEN) IN PREVENTING LIFESTYLE DISORDERS SUCH AS DIABETES AND HYPERTENSION

Lifestyle disorders, particularly diabetes mellitus and hypertension, have emerged as major global health challenges, with their prevalence escalating dramatically in both developed and developing nations. The traditional Indian system of medicine, Ayurveda, offers a comprehensiv...

JANU SANDHI: A COMPREHENSIVE REVIEW FROM AYURVEDIC AND MODERN CLINICAL PERSPECTIVES

Background: Janu Sandhi, anatomically correlated with the knee joint, is one of the most complex and weight-bearing synovial joints of the human body. It plays an essential role in locomotion, stability, posture maintenance, and functional mobility. Due to continuous biomechanica...

CLINICAL AND LITERATURE-BASED REVIEW ON BAL KARSHYA IN PEDIATRICS AND ITS INTEGRATION WITH MODERN NUTRITIONAL REHABILITATION

Bal Karshya represents a classical Ayurvedic pediatric disorder characterized by progressive emaciation, inadequate body weight, poor muscle development, and diminished physical strength. Grounded in the principles of Kaumarbhritya, this condition is primarily attributed to Apata...

AI IN PULMONARY DRUG DELIVERY SYSTEM

Pulmonary drug delivery looks like a solid option for getting meds into the body. It works because of how the lungs are built, with that huge surface area for soaking stuff up, a super thin layer to cross, and all those blood vessels ready to go. Folks have stuck with the usual g...

COMPREHENSIVE REVIEW OF SHRINGATAKA (TRAPA BISPINOSA ROXB.)

Shringataka (Trapa bispinosa Roxb.), commonly known as water chestnut (Singhada), is an important aquatic medicinal plant described under Phala Varga in Ayurveda. It possesses Balya, Brimhana, Grahi and Vrishya properties and is particularly beneficial in Pitta disorders. Owing t...

QUANTIFICATION OF CARMOISINE (E122) IN MUMBAI'S INFORMAL FOOD SECTOR: A VALIDATED SPECTROPHOTOMETRIC ASSESSMENT OF PUBLIC HEALTH RISKS AND REGULATORY COMPLIANCE

The informal street food sector in Mumbai is a vital socioeconomic cornerstone, providing affordable nutrition, caloric density, and a primary source of livelihood for millions of urban dwellers. However, its largely unregulated reliance on synthetic chemical additives, such as t...

METABOLIC PROFILE OF BRAIN AND ADIPOSE TISSUE

Different organs have different metabolic functions and capabilities. In this article we consider how the special needs of mammalian body organs are met and how their metabolic capabilities are coordinated to meet the demands. This review explores the metabolic profile of brain a...

QUANTIFICATION OF CARMOISINE (E122) IN MUMBAI'S INFORMAL FOOD SECTOR: A VALIDATED SPECTROPHOTOMETRIC ASSESSMENT OF PUBLIC HEALTH RISKS AND REGULATORY COMPLIANCE

The informal street food sector in Mumbai is a vital socioeconomic cornerstone, providing affordable nutrition, caloric density, and a primary source of livelihood for millions of urban dwellers. However, its largely unregulated reliance on synthetic chemical additives, such as t...

COST MINIMIZATION ANALYSIS OF ANTIBIOTICS AND ANTACIDS: A COMPREHENSIVE REVIEW

Cost Minimization Analysis (CMA) is a pharmacoeconomic evaluation technique used to compare the costs of therapeutic interventions that have demonstrated equivalent clinical efficacy and safety. Antibiotics and antacids are among the most frequently prescribed medications worldwi...

FORMULATION AND EVALUATION OF HERBAL LIP BALM USING TRITICUM AESTIVUM AND PUNICA GRANATUM

The present study was aimed to design and evaluate a herbal lip balm using natural ingredients such as Triticum aestivum (wheat) peel and Punica granatum (pomegranate) peel. Herbal formulations are gaining increasing importance due to their safety, effectiveness, and eco-friendly...