Research works

Statistical downscaling for projections of future temperature and rainfall over the Lower Chenab Canal command area, Pakistan based on SDSM–CanESM2

Climate change and global warming are major events in the twenty-first century. Lower Chenab Canal (LCC) command area has been reflected as a hot spot, for impact of climate change on agriculture and water availability. The study aimed to project future changes in temperatures an...

Fournier’s Gangrene and Extensive Abdominal Necrotizing Fasciitis Secondary to Perforated Appendicitis Within an Inguinoscrotal Hernia: A Rare Case Report

Fournier's gangrene (FG) is a life-threatening necrotizing infection rarely triggered by an intra-abdominal process. We report an unusual case of FG and extensive abdominal necrotizing fasciitis secondary to a perforated appendix within an inguinoscrotal hernia. A 66-year-old mal...

The effect of education provided to university students on sustainable nutrition: a comparison of ChatGPT and individual nutrition education

This study aims to compare the effectiveness of face-to-face, individually delivered sustainable nutrition education for university students with that of a ChatGPT-generated educational brochure. The Sustainable Eating Behavior Scale, the Sustainable Food Literacy Scale, and the...

Undecidability's Limits: Halting, Incompleteness, and Unsolvable Physics Problems — E8 Intelligence Research

FINDING: Undecidable problems in computation (halting problem, Gödel incompleteness) impose fundamental limits on knowledge, with physical analogs in unsolvable physics problems. | MATH: Halting problem proof: no Turing machine can decide if an arbitrary program halts (reduction...

Niacin Synthesis from 3-Cyanopyridine by Recombinant Escherichia coli: Optimization and Immobilization

Niacin (vitamin B3) is a high-value chemical widely used in the pharmaceutical and food industries. In this study, a recombinant Escherichia coli strain expressing nitrilase from Pseudomonas putida CGMCC3830 was evaluated for the whole-cell biotransformation of high-concentration...

Resilience behaviors as mechanisms for scaling impact in social enterprises

Purpose This study examines how social enterprises build organizational resilience during scaling processes, extending the Nonprofit Resiliency Framework beyond crisis contexts to scaling scenarios. Design/methodology/approach Qualitative research based on 21 in-depth interviews...

Development and Clinical Application of CPAP-Specific Patient-Reported Outcome Measures in Obstructive Sleep Apnea

BACKGROUND: Patient-reported outcome measures (PROMs) are relevant in sleep medicine, but CPAP-specific PROMs for obstructive sleep apnea (OSA) remain insufficiently characterized. We hypothesized that a PROM tailored to CPAP initiation would show acceptable psychometric performa...

Pulp response to cold and electrical sensibility tests in patients with hypothyroidism: an analytical cross-sectional study

Thyroid disorders are the second most common endocrine diseases worldwide. Hypothyroidism has been associated with peripheral neuropathy; however, its potential effects on dental pulp sensibility remain poorly understood. This study aimed to compare responses to cold and electric...

THIN CAPITALISATION AND FINANCIAL PERFORMANCE OF LISTED MULTINATIONAL FIRMS IN NIGERIA

Abstract Taxation constitutes a significant cost that influences corporate financial performance and wealth maximization objectives. In response, multinational firms often engage in tax planning strategies such as thin capitalization to reduce tax burdens. This study examines the...

Pulsed Field Versus Cryoballoon Ablation for Atrial Fibrillation: Procedural Outcomes and Hemolysis-Related Laboratory Changes in a Single-Center Pilot Study

Background and Objectives: Pulsed field ablation (PFA) and cryoballoon ablation (CRYO) are established approaches for pulmonary vein isolation in atrial fibrillation (AF). Given emerging concerns regarding hemolysis following PFA, this pilot study aims to directly compare outcome...

Mapping autonomy in mental health care: a scoping review protocol

Autonomy is regarded as a fundamental principle in the global reform of mental health care, as promoted by the Convention on the Rights of Persons with Disabilities (CRPD) and reflected in various international initiatives aimed at eliminating coercive practices and fostering rig...

The locus coeruleus gateway hypothesis: Noradrenergic integrity as a candidate determinant of amyloid-β clearance efficiency in anti-amyloid immunotherapy for Alzheimer's disease

) status, or tau burden-leave largely unexplained. We propose that a systematically unmeasured upstream variable contributes to this variability: the structural integrity of the locus coeruleus (LC), the principal source of brain norepinephrine (NE), framed as a candidate determi...

Undecidability in Computation and Physics: Fundamental Limits from Halting and Incompleteness — E8 Intelligence Research

FINDING: Undecidable problems (halting problem, Gödel incompleteness) impose fundamental limits on computation and physics, revealing that not all physical questions are algorithmically solvable. | MATH: Halting problem: no Turing machine can decide if an arbitrary program halts...

Translating Complexity into Credible Evidence: Quantum Expert Witnesses in Construction Disputes Arena

Abstract In construction disputes, resolution often hinges not only on the strength of legal arguments but also on the persuasive power of numbers, figures that are frequently complex, contested, and highly consequential. Within this landscape, quantum expert witnesses—independen...

When Does an Accounting Inequality Have Teeth? A landing criterion for the maintenance power bound in prebiotic chemistry, with a first empirical execution

Abstract Background. Prebiotic chemistry has long lacked a common ledger. Synthesis experiments either reconstruct reaction pathways or investigate energetic conditions in isolation; over several decades the two have advanced separately, and the two standard strategies, “lower th...

Spatial distribution of short birth intervals and associated factors among reproductive-age women in Somalia, 2020: a spatial and multilevel analysis

Short birth interval (SBI) is a major contributor to maternal and child morbidity and mortality. In Somalia, a nation experiencing high fertility rates alongside protracted conflict and humanitarian crises, evidence on birth spacing patterns is scarce. This study investigates the...

Real-Time Symptom and Wearable Monitoring May Improve Prediction of Postoperative Recovery in Lumbar Spine Surgery Beyond Standard Measures

BACKGROUND AND OBJECTIVES: Accurately identifying candidates likely to benefit from surgery and addressing modifiable preoperative risk factors are central to optimizing outcomes. Current prediction tools often rely on static clinical data and patient-reported measures, which lac...

Diketopyrrolopyrrole‐Based Cation as a Semiconducting Spacer in Layered Perovskite

ABSTRACT Incorporating π‐conjugated organic spacers in layered “2D” perovskites in order to extend solar light harvesting has remained a challenge, as typically‐incorporated spacers (e.g. phenethylammonium, PEA + ) do not absorb deep into the visible spectrum. Here, we introduce...

Hyperacute Cytokine Kinetics and Early Interleukin-10 Elevation as Predictors of Neurological Outcome in Post-Cardiac Arrest Syndrome

Background: Post-cardiac arrest syndrome (PCAS) involves a complex interplay between systemic inflammatory and compensatory anti-inflammatory responses. The hyperacute kinetics of these cytokines and their incremental prognostic value beyond established brain injury biomarkers re...

Could foods from the Mediterranean diet act as a DNA-protective tool against the mutagenic and genotoxic effects of urban fine air particulate matter (PM0.5)? An exploratory investigation on bacteria and human cell lines

Fine particulate matter (PM 0.5 ) is an emerging public health concern due to its ability to penetrate deeply into tissues and induce oxidative stress–mediated damage, contributing to the development of chronic diseases. Despite increasing exposure in urban environments, its biol...