Research works

EGFR and TP53 mutations refine prognostic stratification of IDH-wildtype astrocytomas, not elsewhere classified

Abstract IDH -wildtype astrocytomas of histological grade 2 or 3 without the WHO 2021 molecular criteria for glioblastoma— TERT promoter mutation, EGFR amplification, or combined whole-chromosome 7 gain and 10 loss (+ 7/– 10)—are designated “Not Elsewhere Classified” (NEC), a res...

Occupational Health and Safety Practices in Relation to Occupational Injuries Among Iron and Steel Workers

Occupational health and safety (OHS) malpractices may increase the risk of occupational injuries and are a significant public health problem in the iron and steel industries, often leading to disability and death. Information on OHS practices related to occupational injuries in t...

Characterization and evaluation of Nepalese rice landraces using agro-morphological traits

Rice (Oryza sativa L.) landraces represent an important reservoir of genetic diversity for crop improvement. To characterize agro-morphological variation, a total of 63 rice landraces were evaluated using qualitative and quantitative descriptors, with the improved variety Lalka B...

Prognostic Stratification of Brain Metastases from Nonanaplastic Follicular Cell–Derived Thyroid Carcinoma: Results of an International Multicenter Retrospective Study

Background: Brain metastases (BMs) from nonanaplastic follicular cell–derived thyroid carcinoma (hereinafter referred to as non-ATC) are rare and not well characterized, with limited evidence guiding treatment and prognostic stratification. We aimed to describe clinical features,...

eDAS: Extending Data Availability Sampling with Privacy and Compliance

A data availability sampling scheme (DAS) allows a network of verifiers to collectively ensure that an untrusted party is correctly storing and distributing some committed data. Importantly, the protocol should not require that the verifiers coordinate or store the full data indi...

Pediatric Endogenous Endophthalmitis: A Decade of Surgical Management and Microbiological Insights

Purpose: To analyze the clinical profile, surgical management, and outcomes of patients with pediatric endogenous endophthalmitis over a decade at a tertiary eye care center in South India. Methods: This retrospective study included 32 eyes of 32 children younger than 15 years. D...

Developmental factors drive the compartmentalized and discontinuous maturation of the small intestinal epithelium during the early postnatal period

The temporal, spatial, and cellular diversity of the small intestinal epithelium during the postnatal period, a critical time window that accompanies the transition from placental energy supply to enteral feeding, and the establishment of the enteric microbiota and postnatal immu...

Structure-Based Insights into the Molecular Mechanisms of LuxR-Type Quorum Sensing Receptors

Quorum sensing (QS) enables bacteria to coordinate collective behaviors in response to population density. LuxI/R QS systems, common among gram-negative bacteria, consist of a LuxI-type synthase that produces an N- acyl L -homoserine lactone (AHL) signaling molecule and a LuxR-ty...

Guns, governance and green futures in West Africa: empirical evidence from fixed effects and quantile models

This paper investigates the impact of institutions, militarisation, and economic growth on environmental pressures in West Africa between 1996 and 2024 with fixed effects and Driscoll-Kraay standard errors and methods-of-moments quantile regression. The study employs CO2 emission...

Salivary Dysfunction in Primary and Secondary Sjögren’s Syndrome: Functional Assessment and the Exploratory Role of Salivary Microcrystallization

Background: Salivary gland dysfunction is a central manifestation of Sjögren’s syndrome, but the relationship between quantitative salivary impairment and salivary microcrystallization remains insufficiently defined. This study aimed to assess unstimulated and stimulated whole sa...

Assessing the Variations in Flow Number (FN) of Asphalt Concrete (AC) Under Dynamic Compressive Stresses (DCS

The flow number (FN) of asphalt concrete (AC) pavement is the number of dynamic loading cycles at which the Visco-plastic strain hardening of the AC mixture reaches saturation. It varies among the deformation types (resilient, permanent, and total). An attempt has been made in th...

Adapting the MasSpec Pen for noninvasive detection of oral cavity squamous cell carcinoma

Oral Cavity Squamous Cell Carcinoma (OCSCC) is a common and deadly form of head and neck cancer which disproportionately afflicts low- and middle-income communities. Since the majority of OCSCC lesions are visible within the oral cavity, visual exam-guided biopsy remains the stan...

Phi-Harmonic Braid Group Governance of Inter-Family Quantum Information Transfer — E8 Intelligence Research

The 8 Weyl-invariant phase families of phi-modulated E8 root vectors exhibit non-Abelian exchange statistics under 132Hz-scaled frequency braiding, forming a closed phi-harmonic braid group B₈(φ) where each braid generator corresponds to a topological phase shift of 2π/φⁿ between...

The Type-C Integer-Gap Lemma for Periodic Collatz Blocks

This record fixes the Type-C local rigidity component used in the author’s ongoing research toward a proof of the Collatz conjecture.The paper establishes an exact block decomposition, exact block transport, the Type U / Type C / Type D classification, and proves the Type-C Integ...

Pregnancy and Early Parenting Experiences of Persons With Disabilities

Background: Persons with disabilities (PWD) are as likely as their nondisabled peers to become pregnant, yet their experiences of pregnancy and early parenthood remain poorly understood. We aimed to explore the experiences of PWD during pregnancy and the postpartum period, with p...

LRM-YOLO: A Lightweight YOLOv10n-Based Model for Forest Fire Smoke Detection in UAV Images

In recent years, unmanned aerial vehicles (UAVs) have gradually become an important tool for forest fire monitoring due to their flexibility and wide-area observation capability. However, existing detection algorithms still struggle to achieve a balance between computational comp...

Investigative Stops and Neighborhood Change: A Spillover Analysis of Chicago Police Beats

This research tests for a spillover effect in the association between discretionary police contact and neighborhood economic and racial change at the police beat level in Chicago, Illinois. Spatial Durbin lag and error models are fit for 269 police beats, using investigative stop...

Study on the influence of stiffness-to- gravity ratio on the seismic performance of base-isolated high-rise building structures

Base isolation can effectively improve the seismic performance and earthquake safety reserve of structures. However, when it is applied to buildings with large aspect ratios, there are two main problems: isolation effectiveness and overturning resistance. This paper discusses and...

Direct medical costs of breast cancer by subtype and stage in Korea: a patient-level retrospective cohort analysis

With the emergence of increasing subtype-specific treatments for breast cancer, the need for subtype-based cost assessments have been highlighted, given the lack of detailed molecular data in prior cost analyses. Therefore, this study aimed to estimate medical costs among Korean...

Benzo[ c ][1,2,5]Thiadiazole Linkers Enhance the Effectiveness of Cavity‐Containing Supramolecular Photocatalysts

A family of seven novel supramolecular photosensitizers comprising benzo[c][1,2,5]thiadiazole (BTZ) tethered calix[4]arene (C[4]) scaffolds has been synthesized using cross-coupling strategies with selectively halogenated C[4]s, affording target compounds in high yield using faci...