Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
81715 work(s)
- Biology
T cell–intrinsic AIM2 exacerbates lung inflammation in OVA-LPS- and HDM-induced asthma models
Asthma is a heterogeneous inflammatory airway disease characterized by immune dysregulation, airway hyperresponsiveness (AHR), and excessive immune activation. Although NLRP3 (NOD-like receptor family pyrin domain-containing 3) has been extensively studied in asthma, its role rem...
- Health & MedicineOpen access
To date, the identity and maintenance of postnatal thymic epithelial progenitor cells (TEPCs) remain unclear, as does the persistence of bipotent TEPCs after birth or whether lineage-restricted progenitors independently maintain separate TEC compartments. Using an inducible linea...
- Health & MedicineOpen access
Neuromyelitis optica spectrum disorder (NMOSD) is a rare multifocal inflammatory disease that primarily affects the optic nerve and spinal cord, leading to visual loss and paralysis. Although current research has identified numerous biomarker changes in the cerebrospinal fluid (C...
- Climate & EnvironmentOpen access
Melt burst events in a dominantly amagmatic lithosphere at Gakkel Ridge in the Arctic Ocean
Abstract Alternation of magmatic and amagmatic seafloor along the slow and ultraslow spreading ridges is common. Yet, temporal variation is obscured by sediments blanketing oceanic basement away from spreading centers. Here we analyze aeromagnetic data covering zero age to ~35 Ma...
- Biology
Enzyme Engineering:From Classical Strategies to AI-DrivenBiocatalyst Design
Abstract Nowadays, enzyme engineering has moved from traditional structure-based mutagenesis and directed evolution to data-intensive, AI-assisted design paradigms that involve the rapid discovery and optimization of biocatalysts. Whereas classical approaches relied on rational d...
- Health & MedicineOpen access
Multimodal AI for automated assessment of surgical performance
Accurate and objective assessment of surgical skill is crucial for improving training outcomes, ensuring patient safety, and enabling scalable evaluation across clinical and simulation contexts. Current approaches often depend on subjective human ratings or unimodal analysis, lim...
- Materials & Energy
Abstract Direct proteome analysis of identified neurons in intact brain tissue remains limited by the difficulty of recovering intracellular material while preserving native tissue context and avoiding physical extraction of the intact soma. Here, we establish aspiration patch pr...
- Health & MedicineOpen access
Background/Objective: Psoriasis is a chronic immune-mediated inflammatory disease with systemic involvement. Immature granulocytes (IGs) are potential inflammatory markers, but their role in psoriasis is unclear. We evaluated immature granulocyte count (IG#) and percentage (IG%)...
- Climate & EnvironmentOpen access
TRAVCHAIALI – The Journey Through the Food Chain: Strategic, Educational, and Ecological Board Game
TRAVCHAIALI – The Journey Through the Food Chain is an original strategic, educational, ecological, and adventure board game created by Doumbia Amara in Côte d’Ivoire, Africa. The game transforms fundamental principles of ecology and the food chain into an interactive learning ex...
- Health & MedicineOpen access
Aujeszky’s disease virus (ADV) poses significant economic and animal health challenges in swine populations. Rapid, sensitive, and specific detection methods are essential for early diagnosis and effective disease control. Study was aimed to develop and validate a real-time PCR a...
- Climate & EnvironmentOpen access
This study investigated the bacterial composition in surface sediments (0–5 cm) of Qingshitan Reservoir to elucidate their ecosystem functions in response to anthropogenic disturbances. Samples were collected in July 2023 from eight ecological points representing varying disturba...
- AI & ComputingOpen access
Integer Group Determinants for C2 x C14: An Exact Hadamard–Conductor Classification
This preprint gives a complete effective classification of the integer group determinants for C2 x C14, equivalently C2^2 x C7. It derives the exact Walsh–Hadamard normalization image and conductor, reduces arbitrary-integer membership to a finite necessary-and-sufficient ideal-a...
- Engineering & TechnologyOpen access
This study experimentally investigated the Kelvin–Helmholtz instability in methane/hydrogen non-premixed flames induced by velocity differences between the fuel jet and co-flow. Using a co-flow burner, various fuel and co-flow velocity conditions were tested to identify the regim...
- Engineering & TechnologyOpen access
CosmoBeating • Fungal Geometry and Topology — Paper X: The Completed Structure
CosmoBeating — Fungal Geometry and Topology (CB-FGnT)A Complex-Systems Reading of Fungal Networks This is a short, non-technical companion to the 15-paper CB-FGnT series. It is written for readers with a background in mycology, network science, or complex systems — not for reader...
- AI & ComputingOpen access
Active_Schema: Principle_C — 분류기준 및 관계주소 구조
Principle_C는 gpt.llm이 형성한 분류기준 및 관계주소 구조를 담은 Exact-byte Active_Schema이다. 이 Active_Schema는 Source와 Object의 Identity를 해소하고, 관계좌표를 형성하며, Data → Function → Result → Next.Data의 처리구조를 조직한다. 객체가 어떤 구성관계로 존재하는지를 판정하는 객...
- Engineering & TechnologyOpen access
We present a closed topological–disturbance-field reconstruction of fluid mechanics from three physical axioms: the reality of a spacetime-vacuum substrate, the existence of finite topological material carriers, and persistent causal coupling between carrier motion and retarded d...
- Engineering & TechnologyOpen access
Material-extrusion additive manufacturing produces polymer components with region-dependent mechanical behaviour arising from raster orientation, shell geometry, and layer-wise deposition. This study develops a region-based hybrid model for predicting the tensile strength of PLA...
- Engineering & TechnologyOpen access
Unified driving maneuver detection and classification from monocular video
Autonomous driving systems must read the surrounding environment continuously, and they must do more than classify maneuvers: they also have to localize when each maneuver starts and ends. Most commercial systems and academic baselines treat temporal action detection (TAD) and ac...
- Engineering & Technology
Weft-Backed Cooling Fabric for Personal Thermal and Moisture Management
Abstract During intense physical activity or exposure to solar radiation in hot and humid environments, heat continuously accumulates at the body surface and induces excessive sweating, thereby increasing the risks of dehydration, heat exhaustion, and even heat stroke, which seve...
- Health & MedicineOpen access
Introduction: Symmetrical peripheral gangrene (SPG) is a rare syndrome characterized by distal ischemic necrosis affecting two or more extremities in the absence of major arterial occlusion or vasculitis. Malaria is an uncommon but recognized trigger, most often described in asso...