Research works

Prognostic significance of isolated tumor cells and nodal tumor burden in endometrial cancer: a population-based cohort study

BACKGROUND AND PURPOSE: Since the introduction of sentinel lymph node biopsy, nodal assessment has expanded to nearly all women with endometrial cancer. However, evidence on the prognostic significance of isolated tumor cells (ITCs) and nodal tumor burden remains limited. We ther...

Can Publicly Available Information Predict the Popularity of Library Materials? A Machine Learning-Based Approach Using Open Loan Data from Public Libraries in South Korea

Recommendation systems in public libraries rely on loan data skewed toward past popularity, making it difficult for unborrowed and newly published titles to reach users. Hence, we propose and evaluate a machine learning-based approach predicting library material popularity using...

A Body Within a Body — Pregnancy, Personhood, and Inner Jurisdiction

This essay examines pregnancy as an embodied relation between unequal scales of life and asks how moral responsibility can recognize developing life without transferring jurisdiction over the pregnant body to another person or the state. It proposes inner jurisdiction—not as abso...

Toward a Metafunctional Theory of Memory: Recursive Triadic Architecture, Temporal Metabinding, and Mnemonic Worldhood

This preprint develops the Metafunctional Theory of Memory (MTM) within the broader Brain Metafunction Framework (BMF). The MTM conceptualizes memory as the organism-level metafunction of continuity organization: the process through which past-derived structures remain operative,...

EXTRACTED CONSTANTS (rlab #107): 1.618, 0.618, 240 — E8 Intelligence Research

constant phi = 1.618 — golden ratio referenced for inter-star arc distance clustering constant phi_inverse = 0.618 — golden ratio inverse for arc distance clustering constant e8_vertex_count = 240 — number of vertices in E8 root system for mapping to celestial holes Author: Andre...

Managing Osgood-Schlatter disease in an adolescent with homoeopathy: A case report

Osgood-Schlatter disease (OSD) is a common cause of anterior knee pain in physically active adolescents. OSD typically presents with a gradual, non-traumatic onset of knee pain localised to the insertion of the patella tendon at the tibial tuberosity. This self-limiting condition...

XrayCLIP: A VLM-Based X-Ray Security Inspection System for Railway Safety

Railway safety is an important component of public security. Ensuring the safety of high-speed rail systems and passengers is also crucial for railway transportation enterprises. The performance of X-ray security inspection systems is one of the key factors in improving intellige...

Efficacy of neuromuscular electrical stimulation as a therapy for sarcopenia in people on haemodialysis: study protocol for the STIM-HD randomised controlled trial

Abstract Background Sarcopenia is highly prevalent among adults receiving haemodialysis and is associated with reduced physical function, impaired quality of life, and increased morbidity and mortality. Although structured exercise programmes can improve muscle health, most peopl...

Estimating the Importance of Floating Surface Material to the Total Phosphorus Transport in Silver Creek, Wisconsin Using Particle Image Velocimetry

Various techniques are used to estimate nutrient delivery in streams that combine flow and water-quality data. However, the transport of surface floating material is difficult to measure, and is therefore typically neglected when stream sampling and in the estimated nutrient deli...

SNX4 promotes glioblastoma progression through the TGFβ1/Smad signaling pathway and represents a potential therapeutic target

Abstract Background Glioblastoma multiforme (GBM) is a highly malignant primary brain tumor that still lacks highly specific and clinically effective molecular targets for GBM treatment. Sorting Nexin 4 (SNX4) is an important regulatory molecule involved in intracellular membrane...

Advances in Smart Responsive Nanofibers for Wound Healing

Wound healing, particularly chronic wound healing, is a complex and dynamically regulated process that is commonly challenged by wound infection caused by the invasion of various bacteria. The emergence of nanofibers has overcome the limitations of traditional wound dressings in...

Off-Target Retinal Pigment Epithelium (RPE) Expression of Cre in the Rhodopsin-iCre75 Mouse Line

Purpose: Cre mouse lines are an important tool to manipulate gene expression in specific cell types and at distinct developmental timepoints. Overlooked and off-target expression of Cre is a common issue with transgenic Cre lines that has confounded the interpretation of many stu...

Coupled Photon Transport and Interfacial Charge Utilization in ACT/g‐PAN for Photocatalytic CO 2 Reduction

ABSTRACT Integrating microscopic catalyst design with macroscopic photophysical reaction engineering is important for improving solar‐driven CO 2 reduction. However, previous studies have largely focused on the molecular‐level optimization of catalysts, whereas the coupled effect...

Defining STING activity

Mapping mutations to cellular outcomes reveals the molecular mechanisms underlying STING activity.

Society for Maternal‐Fetal Medicine Special Statement: Checklists for persons with sickle cell disease in pregnancy

Abstract This article presents checklists designed to guide clinicians in the comprehensive management of pregnant individuals with sickle cell disease, including prepregnancy, antepartum, delivery, and postpartum care, as well as the specific management of vaso‐occlusive crises....

EuroMillions Breakthrough Mining — 1689 Sources, 12388 Leads Extracted — E8 Intelligence Research

Mined 1689 lottery+quantum breakthroughs. Extracted 12388 leads across 13 categories. 10402 high-value leads found. Categories: {"CORRIDOR": 1028, "FORMULA": 872, "GEOMETRIC": 718, "FORWARD_ATTEMPT": 1077, "QUANTUM": 1290, "TIMING": 204, "CELESTIAL": 956, "GEMATRIA": 1024, "CONST...

Authentication of a Heterogeneous Information and Control Network of Autonomous Oceanographic Platforms Based on a SAW-PUF Architecture

Protecting a heterogeneous information and control network of autonomous oceanographic platforms (surface buoys and underwater gliders/probes) requires authentication protocols built on the multichannel AlN-SAW physical unclonable function (PUF) architecture proposed in the autho...

Periodontal Dysbiosis and Psoriatic Arthritis: From Oral Threshold Modification to Post-Enthesitic Synovial Amplification

Abstract Background Psoriatic arthritis (PsA) is not well explained by directly importing the Porphyromonas gingivalis–PPAD–ACPA model from rheumatoid arthritis (RA): PsA is usually seronegative and has an enthesis-centered anatomy. This note develops a distinct hypothesis: chron...

Inspection-Oriented Predictive Quality Modeling for MDF Manufacturing Using Industrial Process Data and Machine Learning

Continuous medium-density fiberboard (MDF) production presents a persistent quality-assurance problem: destructive laboratory tests return results too late to prevent off-specification material from accumulating before a corrective response is possible. This study develops an ins...

AOPQ-Net Acoustic–Optical Proposal Query Network for Underwater Multimodal Object Detection

Optical cameras and imaging sonars are widely used sensors in autonomous underwater vehicles. However, their different imaging mechanisms introduce substantial cross-modal discrepancies in the acquired data. In addition, underwater optical images are often degraded by low illumin...