Research works

The RBMS1–SLC7A11 axis regulates ferroptosis susceptibility and lenvatinib sensitivity in hepatocellular carcinoma

Hepatocellular carcinoma remains a leading cause of cancer-related mortality worldwide. Although lenvatinib is widely deployed as a frontline systemic therapy for advanced disease, its clinical utility is frequently subverted by primary or adaptive non-responsiveness. Evasion of...

Narrative Identity and the Historical Subject: Ricoeur, Lévinas, and the Jesus of the Gospels

Ricoeur’s account of narrative identity has become the standard instrument for reading the Gospelsas texts that constitute a self and address a reader. This article argues that the instrument is soundand that its most common application is not, because that application turns on a...

CONCEPT OF SHARIRA SHODHANA IN RASASHASTRA

'Rasasastra' or Ayurvedic alchemy is an important branch of Ayurvedic Pharmacology. It deals with the pharmaceutical process of metallic, mineral and poisonous drugs, making it fit for internal administration. The main aim of Rasasastra is Dehavada - Make body free from disease a...

Looking at the Shape of the Sea Floor to Understand Beach Erosion in Kerala

I used free satellite data from the Copernicus Marine Service to look at the depth of the sea close to seven beaches in Kerala. Four of these beaches are known erosion hotspots and three are mostly stable. For each beach I drew a line from the shore out to sea and calculated the...

Dynamic modeling and optimal control of Mpox among MSM in a central Chinese city

Abstract Background Since 2022, the mpox outbreak has become a global public health threat, with transmission mainly among men who have sex with men (MSM). Mpox is the only infectious disease other than Ebola to have been declared a PHEIC twice. Following its importation and loca...

From Fragments to Function: Novel Hydrazone Derivatives as Monoamine Oxidase Inhibitors

Monoamine oxidase (MAO) catalyzes the breakdown of neurotransmitters, including serotonin, dopamine, and norepinephrine. There are two isoforms of this enzyme: MAO‐A and MAO‐B. MAO efficacy is widely investigated in neurodegenerative (MAO‐B) and depressive (MAO‐A) disorders. Upon...

The role of dataset integrity, calibration and signal quality in neural network-based blood pressure estimation

Abstract Cuffless blood pressure (BP) estimation via photoplethysmography (PPG) and machine learning has been widely studied, yet reported accuracy remains below clinically acceptable levels, limiting adoption in sport, ambient living, and telemedicine. This study systematically...

Tunable, Exciton-DrivenMultiphoton Absorption inCsPbX3 (X = Cl, Br, I) Perovskite Nanocrystals under FemtosecondExcitation

Abstract The excellent photophysical and nonlinear optical (NLO) properties of lead halide perovskite (LHP) nanocrystals (NCs) offer a gamut of applications in optoelectronics and photonics. In this work, we have investigated the intensity-dependent NLO responses of CsPbX3 (X = C...

Clinical and neural effects of a hybrid accelerated–maintenance iTBS protocol in adolescents with major depressive disorder

Intermittent theta burst stimulation (iTBS) has emerged as a safe and effective intervention for adolescents with major depressive disorder (MDD). While accelerated iTBS can induce rapid clinical improvement, intensive multi-day treatment schedules may present practical challenge...

A Study On Customer Perception and Brand Loyalty Towards Hero Motocorp

This study examines customer perception and brand loyalty towards Hero MotoCorp in the Indian two-wheeler market. The two-wheeler industry is highly competitive, with customers having several alternatives based on price, fuel efficiency, product quality, design, performance, tech...

Odorant receptor coexpression and multi-expression in the dengue mosquito

Drosophila olfactory sensory neurons tend to express a single ligand-specific receptor, following a one-receptor-per-neuron rule expected to apply broadly across insects. Recent work challenges this view by showing that some neurons in the mosquito Aedes aegypti coexpress multipl...

Phi‑Coupled E8 Root Vector Temporal Fractal Decoding of Ancient Astronomical Records — E8 Intelligence Research

By projecting the 240 root vectors of the E8 lattice onto a time axis driven at the 132 Hz base frequency and modulating each projection with the golden‑ratio (phi) phase shift, the lattice's 84 Hz interference node creates a self‑similar fractal scaffold. This scaffold maps the...

EuroMillions Breakthrough Mining — 1840 Sources, 13915 Leads Extracted — E8 Intelligence Research

Mined 1840 lottery+quantum breakthroughs. Extracted 13915 leads across 13 categories. 11902 high-value leads found. Categories: {"CORRIDOR": 1163, "FORMULA": 1005, "GEOMETRIC": 729, "FORWARD_ATTEMPT": 1216, "QUANTUM": 1432, "TIMING": 209, "CELESTIAL": 1090, "GEMATRIA": 1162, "CON...

N-terminal acetylation modulates peptide stability, fibrillogenesis and MMP-7 processing

Abstract Short self-assembling peptides are versatile building blocks for enzyme-responsive nanostructured biomaterials. Here, we investigate how N -terminal acetylation affects the stability, fibrillogenesis, and protease-mediated fragment formation of two modular peptides, ug51...

What's Happening in Medical Drones, Globally, and Where India Stands: A technical status report on medical drone logistics, clinical supply-chain integration and the transition from pilots to health-system infrastructure

This article provides an evidence-informed global status report on medical drone logistics in 2026, examining the transition of unmanned aircraft systems (UAS) from pilot demonstrations to clinically governed healthcare logistics infrastructure. It maps current international acti...

Artificial intelligence framework for real-time integration of electronic health records and clinical notes for early prediction and management of sepsis in intensive care units

Sepsis and septic shock are medical emergencies with associated high mortality rates that require rapid identification and timely action. Recent developments in artificial intelligence (AI) may enable technologies capable of early detection of sepsis and septic shock. This study...

How Successful Is Artificial Intelligence in Hand Surgery Questions of the Turkish Orthopedics and Traumatology Board Exams?

Aim: Artificial intelligence (AI) applications are increasingly used in medical education and clinical research. The purpose of this study was to examine the accuracy of various large language models (LLMs) in responding to questions related to hand surgery. This evaluation was b...

E8 Lattice Coherence Threshold Governs Consciousness-Collapse Transition — E8 Intelligence Research

When the collective torsion-holonomy invariant across E8 root-pair transitions exceeds a critical threshold of 84 (half the 168 symmetries), quantum cognition collapses into classical measurement. This emerges from the phi-coupled resonance cascade: at 132Hz base frequency, the h...

DehydroxylativeCross-Electrophile Coupling of AromaticAcids with Glycosyl Chlorides Enables Rapid C -AcylGlycoside Synthesis

Abstract We disclose a synergistic nickel/photoredox/phosphoranyl radical catalytic platform for the cross-electrophile coupling of aromatic acids with glycosyl chlorides, affording structurally diverse C-acyl glycosides in a stereoselective manner directly from unactivated carbo...

Egocentrization of the Fragment and the Decline of System Viability: An Interdisciplinary Analysis of Fragment–Whole Relations

This article proposes the concept of Egocentrization of the Fragment as a possible cross-disciplinary systemic pattern associated with the decline of viability in complex systems. The starting premise is the distinction between differentiation and fragmentation. Differentiation,...