Research works

The gut microbiome and allograft outcomes: implications for heart transplantation

Heart transplantation remains the gold standard therapy for patients with end-stage heart failure. However, post-transplant complications are considerable. Emerging evidence implicates the gut microbiome as a modifiable determinant of post-heart transplant outcomes through its in...

Emerging roles of ATR beyond DNA damage repair: orchestrating transcriptional reprogramming during epithelial-to-mesenchymal transition

The ability of cancer cells to transition between epithelial and mesenchymal states, a process known as epithelial-to-mesenchymal transition (EMT), is a key driver of cancer metastasis and therapy resistance. While ataxia telangiectasia and Rad3-related (ATR) kinase was originall...

Cacophonies of Metronomes: Multi-sequence Generalizations of Beatty's Theorem

Two multi-sequence generalizations of Beatty's theorem, both derived from a single geometric observation (the Height Lemma) about monotone paths crossing the faces of a cubical tiling of the positive orthant. The first partitions the positive integers into n sieved Beatty sequenc...

Misremembering the past: a failure but not a malfunction

Abstract Episodic memories can fail to represent the past. We often forget, misremember, or make up histories we have never experienced. Yet according to the mnemonic function, episodic memory evolved for encoding, storing, and retrieving tolerably accurate representations of the...

LazyHMC: Hamiltonian Monte Carlo Simulation for Lazy, Infinite Dimensional Probabilistic Programs

Hamiltonian Monte Carlo (HMC) is a successful generic inference method in probabilistic programming, but in its ordinary formulation it needs gradients and finite-dimensional parameter spaces. In Haskell, lazy evaluation lets probabilistic programs express stochastic processes an...

Institutional Aura: On the Intangible Aspects of Materiality and Their Role in Institutional Maintenance

Drawing on institutional theory and the literature on materiality, I address the research question: how are institutions maintained by buildings and the artifacts within them? I specifically focus on the “intangible” aspects of spaces, extending the existing literature on enchant...

Ethical dilemmas or uneasy situations? Using a dialogical reflective method to address intersectional challenges in research conducted by female researchers with male participants

Ethical dilemmas in research are common and often anticipated through institutional review processes, yet some challenges only surface during fieldwork. These unanticipated dilemmas are discussed far less frequently by women researchers, partly due to shame, stigma, or the absenc...

Adaptive optics imaging in bilateral vitelliform maculopathy

This report presents the clinical, electrophysiological and multimodal imaging findings of an individual with bilateral vitelliform maculopathy. Adaptive optics imaging enables in vivo visualisation of retinal microstructure at cellular resolution, providing a detailed baseline f...

Electronic energy loss in tungsten collision cascades: A quantum statistical study of force scales, friction, and stopping

Electronic stopping in collision cascades is formulated as a problem of driven quantum statistical work. The Keldysh influence functional, obtained by eliminating electronic degrees of freedom along the closed time contour, provides a common parent for both equilibrium electronic...

The efficiency paradox of majoritarian democracy

Abstract Majoritarian democracy is widely regarded as the canonical procedure for converting heterogeneous individual preferences into collective decisions, yet its welfare properties are far more fragile than legal and political theorists suggest. This paper contributes to the l...

Asymmetric Dishonesty in Markets: A Field Experiment on Male Sellers and Buyer Gender

ABSTRACT Dishonest behavior is a pervasive phenomenon that imposes substantial economic and social costs on society. While the literature extensively documents gender differences in who lies, far less attention has been paid to whether sellers discriminate in their dishonesty bas...

Acceptability of breast cancer risk assessment for women aged 30–49: Views of women from six under-served groups

Inequalities in breast screening uptake and cancer outcomes persist among under-served women. To reduce disparities, it is essential to understand women’s views when developing proactive early detection and prevention services. This study explored the acceptability of introducing...

Insights Into Public Attitudes for Effective First Responder Communication During a Simulated Mass Casualty Incident

ABSTRACT Effective public communication during Mass Casualty Incidents (MCI) is essential for safeguarding life, maintaining order, and sustaining trust in emergency responders. Yet, high‐pressure, information‐scarce environments make this communication challenging. This mixed‐me...

Climate adaptation as evolvability

Abstract Standard approaches to climate adaptation, commonly understood as the protection of infrastructure, social systems, and ecosystems from adverse climate impacts, are too closely tied to the biological concept of adaptation and the ecological notion of stability . Instead,...

Massively parallel characterization of adolescent idiopathic scoliosis risk variants

ABSTRACT Adolescent idiopathic scoliosis (AIS) is a common pediatric musculoskeletal disorder characterized by lateral spinal curvature, often leading to chronic pain and deformity. While a significant genetic component to AIS is recognized, the functional impact of most associat...

The Implementation and One-Year Evaluation of a Pre-Admission Pharmacist for Obstetric Admissions

(1) Objective: This study aims to evaluate the pre-admission pharmacist for high-risk obstetric patients’ admissions on medication management processes, workflow efficiency, and staff satisfaction. (2) Methods: Data collected over a 12-month period, from March 2025 to February 20...

Mechanism and Energetics of Hydrogen Sulfide Thermolysis from Reactive Molecular Dynamics: Cutoff-Radius Effects, Thermochemically Validated Energy Costs, and the Elementary Reaction Network

Hydrogen sulfide (H2S), a high-volume by-product of the hydrodesulfurization of fossil fuels, can be valorized by thermolysis to recover both molecular hydrogen and elemental sulfur, rather than being oxidized as in the conventional Claus process. The viability of this route depe...

Mechanistic Originsof Enhanced PET Hydrolase Activityfrom Molecular Dynamics and Deep Learning-Assisted Network Analysis

Abstract Polyethylene terephthalate (PET) hydrolase-based biodegradation offers a promising route for plastic waste remediation, yet the dynamic origins of high activity and their linkage across catalytic stages still require further elucidation. Here, we focus on the Leaf-Branch...

Subsurface fault imaging beneath the Seoul metropolitan area using joint inversion of S-wave travel times and Rayleigh-wave dispersion

Constraining seismogenic fault structures is critical in the densely populated area such as the Seoul metropolitan area of the Korean Peninsula, where historical records document damaging earthquakes. Recent increase in clustered seismicity has highlighted the need for improved c...

CXCR4-targeted dual softener for inducing senescence therapy in hepatic fibrosis

Hepatic fibrosis is a central pathological driver of chronic liver diseases, including metabolic dysfunction-associated steatotic liver disease and alcohol-related liver disease, which collectively impose a growing global health burden. Fibrosis is primarily mediated by persisten...