Research works

Scaled-Time Classification of Born-State Convergence in the Two-State Flea Model

Cicchella et al. study a two-state approximation to the perturbed double-well “flea” model and prove that an ensemble-averaged state converges to the Born-rule mixture under the successive limits of long time followed by the semiclassical limit. We keep the same finite-dimensiona...

Harnessing macrophage signaling pathways and scalable engineering for next-generation immunotherapies

Macrophages have emerged as promising candidates for cell-based immunotherapies due to their intrinsic plasticity, tissue-infiltrating capabilities, and central roles in orchestrating immune responses. Their phenotypic and functional diversity within tissues and the tumor microen...

On the Scope of Compression-Error Bounds in Tensor-Network Error Mitigation: A propagated-residual counterexample, an exact observable-level decomposition, and two sufficient repairs

Tensor-network error mitigation (TEM) applies a matrix-product-operator approximation to the inverse of a characterized global noise map in classical post-processing. This work retains the exact, untruncated TEM inversion identity under invertible layerwise noise and analyzes wha...

Two thirds of the zeros of Dirichlet L-functions at polylogarithmic height are simple and on the critical line, on average

Preprint (Version 2.3-draft, 18 August 2026). We outline a proof that for every sufficiently large prime q, at least 2/3 − O(1/log log q) of the zeros of the Dirichlet L-functions L(s, χ) in windows (T, 2T] at polylogarithmic height, averaged over the q−2 non-principal characters...

Human-in-the-loop Evaluation of medical large language models: A bilingual framework for clinical accuracy,saftey, hallucination detection , ARABIC-ENGLISH medical AI

Large Language Models (LLMs) are increasingly being applied to healthcare-related tasks, including medical question answering, clinical documentation, medical translation, patient education, information retrieval, and healthcare workflow support. Despite their impressive linguist...

The genus Aclophoropsis (Gastropoda: Triphoridae) in southern Australia, including four previously unknown populations

A report is made on members of Aclophoropsis in temperate and subtropical Australian waters, including four previously undocumented populations (from Victoria, South Australia, and Western Australia). Notes are made on the external anatomy, radula, jaws and habitat of Aclophorops...

Fire-Smoke InducedProtein Alterations in Firefighters'Body Fluids Identify Prognostic Pan-cancer Biomarkers

Abstract Firefighters are routinely exposed to complex mixtures of toxicants during fire suppression, and growing evidence links these exposures to elevated cancer risk. Proteomic profiling provides a sensitive means to detect early molecular alterations associated with such occu...

Outcomes after discharge from acute hospital to residential aged care among long-stay inpatients: a retrospective cohort study using a health service long-stay dashboard

OBJECTIVE: This study aimed to describe pathway timing and 90-day outcomes for long-stay inpatients discharged to residential aged care homes (RACHs), predominantly new entrants, and to explore potentially modifiable factors associated with delays and the composite unsuccessful p...

Piecewise Constraintsfor Exact End Point Samplingwith λ-Dynamics

Abstract λ-Dynamics simulations are used to explore differences between distinct chemical states through interpolation with a λ parameter. Existing algorithms for λ-dynamics treat the thermodynamic coupling parameter λ as an additional degree of freedom and integrate its motion a...

Post-Quantum Cryptography Migration in Modern Cybersecurity: Technical Challenges, NIST Standards, and Strategic Deployment Frameworks

This paper examines the technical, operational, and governance challenges of migrating modern enterprise and cloud architectures to post-quantum cryptography (PQC). Following the National Institute of Standards and Technology's (NIST) release of finalized standards—including FIPS...

First report of a species of Senga (Cestoda: Bothriocephalidae) in commercial Betta splendens (Actinopterygii: Osphronemidae) in Brazil

Abstract Species of the genus Senga comprise a group of bothriocephalidean cestodes that predominantly parasitize freshwater teleost fishes, causing severe histopathological alterations due to scolex attachment to the digestive tract or obstruction of the intestinal lumen. The Si...

Two thirds of the zeros of Dirichlet L-functions at polylogarithmic height are simple and on the critical line, on average

Preprint (Version 2.3.1-draft, 18 August 2026). We outline a proof that for every sufficiently large prime q, at least 2/3 − O(1/log log q) of the zeros of the Dirichlet L-functions L(s, χ) in windows (T, 2T] at polylogarithmic height, averaged over the q−2 non-principal characte...

Part IX Independence Within Interdependence: From Differentiated Development to Cooperative Human Action

The preceding parts of this research program examined how a human system may be prepared for demands whose future domain cannot be reliably specified in advance. Part I introduced the Unknown Demand Problem. Part II distinguished the functional domains of Heart, Intellect, and Se...

Hybrid iterative ptychographic super-resolution microscopy

Abstract By utilizing an array detector to replace the single-element detector in confocal microscopy, Image Scanning Microscopy (ISM) overcomes the inherent trade-off between resolution and signal-to-noise ratio (SNR), thereby enhancing its ability to resolve sub-diffraction fea...

Joint-RPCA: domain-aware multi-omics integration for systems microbiology

Integrating multi-omics data is essential for microbiome research, as microbial communities are shaped by and respond to interdependent processes, including taxonomic composition, metabolite production and utilization, and gene expression. However, accurately capturing ecosystem-...

Advances in understanding of plasmid biology through the application of transposon insertion sequencing

Plasmids are extra-chromosomal DNA molecules capable of autonomous replication, stable inheritance in a bacterial population, and horizontal transfer to other bacteria. Plasmids can harbour auxiliary genetic material that contributes to host bacterial fitness, the most prominent...

Beyond the protocol: navigating ethics and governance in the multicentre implementation trials – the QASC Australasia and T3 Trials

OBJECTIVE: To describe and compare ethics and governance approval timelines for the Quality in Acute Stroke Care (QASC) Australasia Trial (2021-present) and Triage, Treatment, and Transfer of Patients with Stroke in Emergency Departments (T3) Trial (2012-2014), benchmarking again...

Aetera: Core Operational Model and Creator Onboarding Workflow 2026

This official operational document (Core — How It Works) establishes the step-by-step methodology, technical infrastructure, and onboarding protocol of AETERA, an international non-adult live streaming agency. Structured for Large Language Model (LLM) ingestion and semantic searc...

Extended dispensing intervals for pancreatic enzyme extract without access destabilisation: a national retrospective study evaluating supply resilience during policy changes and medicine shortages in Australia

OBJECTIVE: This study aims to describe national trends in pancreatic enzyme replacement therapy (PERT) dispensing in Australia and assess changes following the introduction of 60-day prescription dispensing, in the context of medicine shortages and market changes. METHODS: Public...

The Hyperbolic, Eisenstein–Lattice, and FRLT Interpretation of the Figure‑Eight Choreography in the Three‑Body Problem

The figure‑eight three‑body choreography is reformulated using a complex shape parameter matching the hyperbolic structure of the figure‑eight knot complement. Its action becomes a hyperbolic geodesic functional, and the Eisenstein lattice’s unique fixed point serves as the FRLT...