Research works

Fast Sine-Transform Preconditioning for Global-in-Time Fractional Diffusion

Time-fractional diffusion equations describe subdiffusive transport in heterogeneous media, but their numerical treatment is complicated by the nonlocal Caputo derivative and by the weak singularity that the solution develops at the initial time. We study a global-in-time discret...

Epigenetic Modulation by Luteolin, Quercetin and Apigenin in Systemic Lupus Erythematosus and Rheumatoid Arthritis: Mechanisms and Therapeutic Perspectives

For many years, plants have long served as sources of potential therapeutic agents. Recently, there has been a growing interest in investigating the effects of plant bio-active compounds on epigenetic modulation of several processes—among them, modifications of DNA, histones, and...

AI-Derived Pericardial Effusion Volume and Long-Term Mortality After Transcatheter Aortic Valve Implantation

Background: Pericardial effusion is a common finding on pre-procedural computed tomography (CT) in patients undergoing transcatheter aortic valve implantation (TAVI). However, its clinical significance remains uncertain. Using artificial intelligence (AI)-based image analysis, we...

Effects of carbohydrate counting training versus standard nutritional and medical therapy on glycemic control and sarcopenia in type 2 diabetes: an open-label randomized controlled trial

Abstract Introduction Carbohydrate counting training is recommended for patients with type 1 diabetes as it has been proved to be effective in providing glycemic control. However, there is limited evidence of this training on glycemic control in patients with type 2 diabetes. Fur...

The Functional Impingement Subacromial Ultrasound (FISUN) test: a conceptual and methodological framework for functional assessment of the subacromial space

Ultrasonography (renamed from the Journal of Korean Society of Ultrasound in Medicine in January 2014), the official English-language journal of the Korean Society of Ultrasound in Medicine (KSUM), is an international peer-reviewed academic journal dedicated to practice, research...

“Nobody Wants to Die That Way”: The Intersection of Immigration Enforcement and Emergency Medical Services in a Rural South Texas County

Abstract The purpose of this study was to explore the influence of migration and immigration enforcement on this inland, rural community’s EMS clinicians and first responders. We conducted 13 in-depth interviews with emergency responders in a rural county in Texas. Interviews wer...

Preclinical evaluation of naturally derived viral nucleic acids in combination cancer immunotherapy

Abstract Effective cancer immunotherapy often requires coordinated activation of innate and adaptive immune responses. While the previous studies have primarily focused on whole oncolytic viruses, synthetic or engineered viral nucleic acids, or inactivated viral particles, the th...

No New Mathematical Insight Found for Navier-Stokes Problem — E8 Intelligence Research

FINDING: No new mathematical insight or discovery; the search results are primarily expository videos and one unverified arXiv preprint claiming a solution to the Navier-Stokes existence and smoothness problem. MATH: The Navier-Stokes equations for incompressible flow: \[ \frac{\...

Self-Governance of Common-Pool Resources Under Rapid Urbanisation: The Case of Lake Hawassa, Ethiopia

Contemporary common-pool resource (CPR) theories recommend self-governance as an effective management approach. This article investigates the implications of rapid urbanisation on CPR self-governance, using Lake Hawassa in Ethiopia as a case study. Drawing on semi-structured inte...

Valley-Polarized Transport in Graphene Induced by Asymmetric Strain and Ferromagnetic Modulation

In this work, we theoretically investigate the valley-dependent electron transport properties of graphene modulated by two strained regions and a single ferromagnetic stripe based on the Dirac equation and the transfer-matrix method. By constructing a multi-region model, the cond...

A maize canopy phenotypic traits detection method based on improved Mask2YOLO cascade deep learning network

High-throughput detection of phenotypic traits of the maize canopy is significant for cultivar selection, cultivation, and management. Addressing the difficulty of rapidly recognizing maize canopy organs from field-acquired images, this study proposed a maize canopy phenotypic tr...

Oxindole-pyrrole-piperazine hybrids as novel α-glucosidase inhibitors: Design, synthesis and evaluation

α-Glucosidase acts as one therapeutic target for diabetes. For finding novel α-glucosidase inhibitors, oxindole-pyrrole-piperazine hybrids ( OPP-1∼24 ) were synthesized. Inhibition evaluation revealed that all hybrids ( OPP-1∼X24 ) demonstrated potent α-glucosidase inhibitory act...

Closed-Face Integrality and Exact Conditional Termination for Cone-Monotone Integer Equality Relations

This paper gives an exact characterization of conditional termination for a class of nondeterministic homogeneous integer equality relations defined by Bλ = Aλ′ over nonnegative integer coefficient vectors. Under pointedness of the source cone, nonzero source generators and cone-...

Soil Yeasts from Sugarcane Agroecosystems: Nutrient Cycling and Biocontrol Potential in Agricultural Systems

Soil yeasts represent a significant component of the agricultural microbiota and possess high ecological and biotechnological potential in production systems such as those for sugarcane. This review analyses the importance of these microorganisms in fundamental processes related...

Hormone therapy ( HT ) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an...

A Cross-Sectional Study of Food Insecurity, Mediterranean Diet Adherence, and Gut-Derived Metabolites and Their Associations with Glycemic Control and Macrovascular Complications in Adults with Type 2 Diabetes

Objective: This study aimed to investigate the combined associations of food insecurity and Mediterranean diet adherence with glycemic control and to determine whether gut-derived metabolites differ according to food insecurity and macrovascular complication status in adults with...

Bioinspired Wettability Engineering Enables Efficient Exhaled Breath Condensate Harvesting for Wearable Respiratory Monitoring

Abstract Efficient collection of exhaled breath condensate (EBC) remains a major challenge for wearable respiratory monitoring because limited sample yield often compromises analytical sensitivity and signal reliability. Herein, we report a smart bioinspired mask that enables eff...

Nature-Based Solutions for Office Workers: A Randomized Controlled Trial on Indoor Plants to Enhance Well-Being and Productivity

Most of the global population lives and/or works in urban areas with limited access to green spaces. Integrating nature-based solutions (NBS) into indoor environments has emerged as a promising intervention strategy for enhancing indoor environmental quality (IEQ) and promoting h...

Fe(III)-MediatedOxidative [5 + 1] Cyclization forthe Highly Site-Selective Synthesis of Functionalized Quinoline Derivatives

Abstract We describe a method for the construction of highly functionalized quinoline derivatives from enaminones via an oxidative [5 + 1] cyclization. A plausible mechanism may involve a cascade sequence including single-electron transfer (SET), radical Michael addition, elimina...

The Hyperspherical Radius as Cosmic Time — a Geometric Hypothesis for Cosmological Expansion and Quantum Nonlocality

This note is a versioned corrigendum to The Hyperspherical Radius as Cosmic Time (Version 6). It records three changes that the reader of Version 6 must apply. First, Version 6 omitted the substantial prior literature on linearly expanding cosmologies; the relevant antecedents an...