Research works

Advancing Physical Therapy: Integrating Biomechanics, Neuroscience, and Systemic Health

Physical therapy has undergone substantial evolution in recent decades, extending beyond post-surgical and post-traumatic rehabilitation to encompass prevention, health promotion, differential screening, and the management of complex movement-related conditions [...]

Tea Beverage-Dependent Reduction in Risperidone Concentration Following Mixing with Risperidone Oral Solution

Risperidone (RIS) oral solution has a bitter taste and is sometimes mixed with beverages to improve palatability and medication adherence. Although the package insert advises against mixing with tea beverages, the effects of beverage type and tea leaf variety on RIS concentration...

miraIRIDE: a Covered Progressive Index at Sixteen Bytes per Key

"The best pointer is the one that does not exist." miraIRIDE is a covered exact-lookup index for immutable data whose entire structure — projections, references, values, chaining — costs 16.3 bytes per key, measured, while answering batched point queries at roughly twice the spee...

Early diagnosis and successful management of an abdominal ectopic pregnancy in a low-resource setting: a case report

Abdominal pregnancy is a rare but potentially life-threatening form of ectopic pregnancy in which the fertilized ovum implants in the abdominal cavity. This serious obstetric condition often remains undiagnosed until the end of the pregnancy and carries a high risk of massive ble...

Sensitivity Study of the Reactivity-Equivalent Physical Transformation Method for Fluoride Salt Coolant Pebble Bed Reactor Lattice

Conventional dispersed-particle fuel systems, such as TRISO fuel, exhibit typical double heterogeneity. The Reactivity-equivalent Physical Transformation (RPT) method can convert a double-heterogeneity system into a single-heterogeneity system by simplified geometric modelling. I...

Assortment Optimization for the Multinomial Logit Model with Repeated Customer Interactions

This paper presents the multinomial logit model with repeated customer interactions. In each period, the same customer selects a product from the recommended assortment or opts out. From the seller’s perspective, the choice probability in the current period is updated based on th...

Beyond “elementary”

Abstract This article examines recent policy debates surrounding the “Elementary Proficiency in a Second Language” (EPSL) requirement at a U.S. liberal arts college, focusing on how misconceptions about language learning and assessment shape curricular decision-making. Drawing on...

Robotic Kidney Transplantation With Grafts With Multiple Arteries: A Single-center Experience and Outcome Analysis

Background. Although robotic kidney transplantation (RKT) is an emerging minimally invasive surgical technique, graft anatomical variations such as multiple renal arteries (MRAs) remain a perceived limitation to its broader dissemination. This study evaluates the feasibility and...

Quantum technologies in clinical medicine: a systematic cross-domain synthesis and translational readiness taxonomy

Abstract Quantum technologies — encompassing quantum sensing, quantum computing and machine learning (QML), quantum nanomaterials, and quantum cryptography — represent an emerging class of physical and computational tools with the potential to address fundamental limitations in c...

Grassroots Governance for Sustainable Environmental Planning: Examining Manila Bay as Limit Case for Participatory Policy Implementation

Abstract In governance and social policies for environmental planning, communities are often engaged for decision-making, aspiring to fulfill democratic ideals. However, community participation is usually limited to decision making; policy implementation seems outside the scope a...

Environmental sustainability management in social service nonprofits: insights into drivers, challenges and opportunities

Purpose Social service nonprofit organizations (SocS-NPOs) have evolved to adopt an entrepreneurial mindset, while also fulfilling their social missions. Balancing different institutional logics, like in their case the business, social-welfare and government logic, is challenging...

Health-related quality of life inequalities among patients with T2D in armed-conflict affected populations in Tigray, Northern Ethiopia

War causes tragic loss of life, destruction, and long-lasting quality-of-life distress in armed-conflict-affected populations. After conflict emerged between the federal government of Ethiopia and the Tigray regional government, the destruction of healthcare facilities and the bl...

Bad Blood: Navigating VTE Risk in Breast, Ovarian, and Endometrial Cancer

Cancer-associated thrombosis (CAT) is defined as venous or arterial thrombotic events occurring in patients with active malignancy or during anticancer treatment, most commonly presenting as venous thromboembolism and representing a leading cause of morbidity and mortality in onc...

Danburstotug, an anti‐ PD ‐ L1 antibody, in relapsed/refractory extra‐nodal natural killer/T‐cell lymphoma: The phase 2 DISTINKT study

Summary Relapsed/refractory extra‐nodal natural killer/T‐cell lymphoma (R/R ENKTL) has limited treatment options. Danburstotug, an antibody targeting programmed death‐ligand 1 (PD‐L1), was evaluated in adults with R/R ENKTL in a phase 2, open‐label study (NCT04414163). Danburstot...

Dual Lattices, Toric Varieties, and Tropical Geometry in Crystallography — E8 Intelligence Research

FINDING: Toric varieties are defined by dual lattices M and N, forming the foundation for tropical geometry and crystallographic symmetry analysis. | MATH: Dual lattices M ≅ ℤⁿ, N ≅ ℤⁿ with pairing ⟨ , ⟩: M × N → ℤ; fans Σ ⊂ N_ℝ define toric varieties X_Σ; tropical curves arise a...

Performance metrics in systematic reviews and meta-analyses of artificial intelligence-based prediction models for children and pregnant women: protocol for an umbrella review

Artificial intelligence (AI) has shown significant promise in medical diagnostics. However, children and pregnant women represent “vulnerable populations” often underrepresented in large-scale training datasets. This paper summarizes a protocol for an umbrella review aiming to id...

The Role of Thalassaemic Red Cells in the Mechanism Process of Hypercoagulable State in Thalassaemia

Background: Thromboembolic events (TEEs) are recognized complications in thalassaemia, arising from a hypercoagulable state driven by multiple proposed mechanisms. These concerns have prompted numerous investigations to better understand the underlying prothrombotic pathways. Thi...

p21 Inhibition Rescues Radiation‐Induced Osteogenic Dysfunction and Promotes Bone Regeneration in Osteoradionecrosis of the Jaw via the Rb–Smad2/3–Runx2 Axis

ABSTRACT Background Osteoradionecrosis of the jaw (ORNJ) is a severe radiotherapy complication with unclear molecular drivers. CDKN1A/p21 is upregulated by radiation‐induced DNA damage, but its role in ORNJ remains unknown. Methods An ORNJ mouse model was established. Single‐cell...

Parathyroid Hormone Levels at Transplant and Outcomes in Renal Transplant Recipients: A Single-Center Retrospective Study

Background: Patients with end-stage kidney disease commonly develop hyperparathyroidism, which may impair muscle strength and physical function. Elevated parathyroid hormone (PTH) levels have been associated with weakness and poor Timed Up and Go (TUG) test performance. We hypoth...

Ontology-Driven Modeling and Semantic Integration of Attack, Protection, and Risk Domains in Electric Vehicle Charging Systems

Electric Vehicle Charging Systems (EVCSs) have become a critical component of the global transition toward sustainable and intelligent transportation. However, their tight integration with heterogeneous cyber–physical, vehicular, and cloud-based infrastructures exposes them to an...