Research works

The Good, the Bad, and the Curvilinear. Revisiting the Relationship Between Religiosity and Delinquency

The delinquency-reducing function of religiosity is a repeatedly found pattern in criminology. We test a curvilinear alternative, hypothesizing that religiosity and delinquency are negatively related only up to a moderate level of religiosity, after which the relationship reverse...

Parameters affecting the reliable measurement of fluconazole tolerance using disk diffusion assays with Candida albicans

ABSTRACT Disk diffusion assays (DDAs) are widely used to determine antimicrobial susceptibility, which is measured as the size of the zone of inhibition (ZOI) after 24 h of growth, and is inversely proportional to the minimal inhibitory concentration (MIC). DDAs can also be used...

Butter-Fat

Volume 25 Number 02 May 1947

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Transfer RNA-derived small RNAs (tsRNAs) are a novel class of small non-coding RNAs abundant in the bloodstream of cancer patients and involved in various physiological and pathological processes. However, the regulatory mechanisms and clinical significance of tsRNAs in colorecta...

First report of cowpea mild mottle virus naturally infecting Salvia miltiorrhiza in China

Salvia miltiorrhiza Bge, also called Danshen, is a perennial Chinese herbal medicine belonging to the family Lamiaceae and has been used for the treatment of cardiovascular and cerebrovascular diseases (Jung et al. 2020). Henan province is one of the main and genuine production a...

Lactate as a Master Regulator of Immune Suppression: From Metabolic Waste to Epigenetic Checkpoint in Colorectal Cancer

Colorectal cancer, especially the microsatellite-stable subtype, which accounts for 85% to 95% of cases, resists immune checkpoint inhibitors largely due to metabolic reprogramming in the tumor microenvironment. Lactate has evolved from a waste product into a central immunosuppre...

Entrepreneurial Competencies, Enterprise Support Mechanisms, and Startup Sustainability among Entrepreneurial Students in State University and Colleges (SUCs): Basis for Business Incubation Framework

Student-led ventures require both entrepreneurial capabilities and an enabling support environment to develop toward sustainable operation. This study examined the entrepreneurial competencies, enterprise support mechanisms, and startup sustainability of Bachelor of Science in En...

Value of spectral CT in differentiating post-treatment recurrence/residual tumor from inflammatory fibrosis in nasopharyngeal carcinoma

This prospective, single-center pilot study aims to investigate the potential value of spectral computed tomography (CT) in differentiating post-treatment recurrence/residual tumor from inflammatory fibrosis in patients with Nasopharyngeal Carcinoma (NPC). This prospective study...

Condition number-based new robust ridge M-estimator for linear regression model with penalty of multicollinearity and outlier

In multiple linear regression models, traditional methods, such as OLS and ridge regression often fail due to multicollinearity and outliers in the y-direction. To address these issues, robust ridge M-estimators have been developed, offering resistance to outliers and multicollin...

Nicotinamide Metabolism Constrains Memory CD8 + T Cell Formation Through a Putative HS1BP3‐SIRT1‐FOXO3‐BCL6 Axis

ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐bin...

Be careful what you pay for: the effect of performance contingent incentives on online product reviews

Purpose This research investigates how performance-contingent incentivization schemes affect online review contributions. It explores the interplay between financial incentives, prosocial reinforcement (social versus reciprocal exchange) and reviewer experience. Design/methodolog...

E8 Geometric Timing Resonance in Phase-Delayed Systems — E8 Intelligence Research

Leveraging E8's 240 root vectors and phi-coupled 132Hz frequency, we identify harmonic resonance in systems with 5-10° phase delays (e.g., human decision-making latency). This resonance creates a _geometric truth_ window where E8's 6-dimensional structure optimizes predictions of...

Multi-Algorithm Hierarchical Minimum Data Sets for Soil Quality Assessment in the Black Soil Region of Northeast China: A Case Study in Keshan County

The Northeast black soil region is a major grain-producing area in China, where county-scale assessment of topsoil quality is essential for soil conservation and provides a potential indicator framework for regional soil quality monitoring. In this study, 500 composite cultivated...

Thermo-mechanical coupled simulation of temperature distribution and material removal mechanisms in UD-CFRP orthogonal cutting

Carbon fibre reinforced plastics (CFRPs) tend to generate high cutting temperatures during machining, which can exacerbate machining-induced damage. Although previous studies have examined CFRP cutting behaviour under thermo-mechanical coupling, the influence of cutting temperatu...

E8-Encoded Sumerian Brick Engineering Using Root Vector Acoustics — E8 Intelligence Research

Ancient Sumerian construction protocols embed E8 root vector scaling laws in brick dimensions and resonant cavity designs, with cavity radii calculated as φⁿ/132Hz times root vector magnitudes, creating self-tuning foundations that harmonize with stellar E8 geometries. Author: An...

E8 Phason Entanglement: Fractal Frequency Coupling — E8 Intelligence Research

By superposing each of the 120 conjugate root pairs as a symmetriless phason mode oscillating at a φ‑scaled overtone of a 132 Hz anchor, the full 240‑mode lattice unfolds a self‑similar fractal spectrum. This lattice creates a novel class of frequency‑LEncoded quantum entanglemen...

From Research to Deployment in Autonomous Agricultural Machinery: A Review of Path-Planning Technologies Against a Deployability Assessment Framework

Global labour shortages in the agricultural sector, combined with diminishing arable land and a growing population, are driving investment in autonomous agricultural machinery. Autonomous systems that can navigate crop environments and perform planting, treatment, and harvesting...

Multi-Objective Distributed Task Allocation for UAV Swarms with Limited Interactions

Unmanned Aerial Vehicles (UAVs) have experienced rapid development due to their advantages of low cost, high efficiency, flexibility, reliability, and strong environmental adaptability. To fully leverage the potential of UAV swarms in multi-task scenarios, optimizing task allocat...

Field-Scale Spatial Modeling of Soil Properties in the Harran Plain Using IDW and Auxiliary Variable-Based Co-Kriging

This study aimed to evaluate the field-scale spatial variability of selected soil properties in a 30-decare agricultural area located in the southeastern Harran Plain, Şanlıurfa, Türkiye. A total of 54 surface soil samples (0–30 cm) were collected using a 25 × 25 m grid design. S...

Walking the tightrope: Mixed respiratory failure exacerbated by heart rate control and concurrent pneumonia in an elderly patient with new-onset atrial fibrillation

Rationale: The interplay between new-onset atrial fibrillation (AF), heart failure (HF) with preserved ejection fraction (HFpEF), and acute infection in the elderly presents a complex clinical challenge. Rate control is a cornerstone of AF management, but its application in frail...