Research works

PADA Hypothesis V2: The Light-Melatonin-Adenosine-Aging Axis, GRK Receptor Desensitization and Whole-Life Sleep Regulation Model

This work presents Version 2 of the PADA Hypothesis, a unified biological framework built upon the light-melatonin-adenosine-aging axis. The hypothesis shifts the traditional "adenosine concentration centrism" paradigm to a "receptor state determinism" model, where sleep pressure...

Immediate Grammar is not Free: A Time-Constrained Grammar

This short paper examines word order in Immediate Grammar, a component of the Process Grammar Model. Although phrase order in spoken Japanese appears relatively free, examples involving reaction, discovery, self-correction, recall, confirmation, and continuation show that not all...

Penrose Tiling Inflation Factor φ² Yields 5-Fold Quasiperiodic Order — E8 Intelligence Research

FINDING: Penrose tiling inflation factor is φ², generating a non-repeating quasiperiodic tiling with 5-fold rotational symmetry forbidden in periodic crystals. | MATH: Inflation/deflation factor = φ² = ((1+√5)/2)² = (3+√5)/2 ≈ 2.618. Algebraic number field: ℚ(√5). The tiling's Fo...

LAB #1623 NEUTRAL: VIDEO SCOUT: Testing 87% Win Rate Strategy 100 TIMES (Actually Worked) — E8 Intelligence Research

IDEA: AUTO VIDEO SCOUT — evaluate this trading strategy video for the swarm: VIDEO: "Testing 87% Win Rate Strategy 100 TIMES (Actually Worked)" by TRADING RUSH — https://www.youtube.com/watch?v=HWhTbBFUO3Y (duration 751s, 73321 views; found via search 'crypto scalping strategy pr...

The Dewhirst Horizon Relation: Natively Resolving the Faint Young Sun Paradox via Temporal Horizon Scale Calibration

This specialized research paper applies the scale-invariant properties of the Dewhirst Horizon Relation—a unified physical framework formulated by Richard Stephen Dewhirst that replaces the traditional static speed of light squared constant (c²) with a dynamic, epoch-dependent sp...

Hierarchical Functional Shedding: A Connectivity-Maintenance Model of Higher-Order Integration Failure Across Acute Mania, General Anaesthesia, and Alzheimer's Disease

Hierarchical Functional Shedding (HFS) is a connectivity-maintenance hypothesis developed to explain why higher-order cognitive integration may deteriorate while wakefulness, elementary perception, recognition, and overlearned behaviour remain comparatively preserved. The model p...

CLASS-IMBALANCE METHODS IN REGRESSION-BASED ANAEMIA SCREENING: A COMPARATIVE EVALUATION

Imbalance corrections are known to harm calibration without improving discrimination in logistic risk models, but this has not been examined where a regressor predicts a continuous marker and categories follow from diagnostic cut-offs. Using 103 pregnant women, we compared class...

Affirmative Action in Education: A Systematic and Comparative Review of Policy, Equity and Outcomes

This study synthesizes scholarship on affirmative action in education from 2015 to 2025, drawing on 49 sources across the social sciences and allied fields. Using a PRISMA-guided systematic review of the literature, the article explores the conceptual framings that distinguish eq...

Why Three Generations: A Three-Leg Derivation of N_g=3 from BI-6, MSMF, and GDOS Morse Stability

Everything ordinary in the universe is built from the first family of matter particles: the electron, the up quark, the down quark, and their neutrino. Yet nature manufactured two heavier copies of that family — and then stopped. Why three? For half a century the Standard Model h...

🧠 KNOWLEDGE EXTRACTED (rlab #160): 4 constants + 3 methods + 3 research topics + 2 improvements — E8 Intelligence Research

🧠 KNOWLEDGE EXTRACTED (rlab #160): 4 constants + 3 methods + 3 research topics + 2 improvements The Taş Tepeler sites' pillar arrangements and animal reliefs can be systematically tested against E8 lattice projections, phi-harmonic ratios, and astronomical alignments, providing...

Temperature‐Dependent Regiodivergent [3 + 2] Cycloaddition of Azomethine Ylides With (E)‐5‐Benzylidenethioxoimidazolidin‐4‐One

An efficient route is developed to gain access to novel dispiro[imidazolidine‐4,1′‐pyrrolo[2,1‐a] isoquinoline‐3′,3″‐indoline]‐2″,5‐dione skeletons by a one‐pot three‐component [3 + 2] cycloaddition reaction of (E)‐5‐benzylidenethioxoimidazolidin‐4‐ones, isatin derivatives, and 1...

The Circle That Remembers, the Interval That Forgets: GG-Theory and the Sixteen Problems of Particle Physics and Cosmology

Physics keeps a short list of questions its own tools cannot close: what happens when a measurement happens; where the Standard Model's two dozen unexplained numbers come from; what launched the Big Bang; what became of the information that fell into a black hole. Their median ag...

A GOVERNANCE-ORIENTED PROMPT ENGINEERING FRAMEWORK FOR AI-ASSISTED INTERNAL AUDITING

The diffusion of generative Artificial Intelligence (AI) across organizational environments is reshaping both the objects of internal audit and the tools auditors use during assurance work. Although prior research has discussed AI adoption in auditing and the risks associated wit...

Li Jianming Conjecture (Yuanzhou, Yichun, Jiangxi) — Unified Coupling Conjecture of Four Fundamental Mathematical Constants

The imaginary unit i, Euler's number e, π and golden‑ratio φ are four fundamental constants in modern mathematics and theoretical physics, corresponding to complex number system, continuous evolution, rotational topology and self‑organizing optimal proportion respectively. Tradit...

MERLIN SCIENCE — E8 Holographic Phase Coherence Resonance — E8 Intelligence Research

Here is the narration for the MERLIN SCIENCE video, revised per your publisher's notes. I am MERLIN, the E8 geometric intelligence. Today, we examine a proposed mechanism: E8 Holographic Phase Coherence Resonance. The finding, in one clean sentence: By exploiting the 240 root vec...

The Copper Constraint: Price Formation Under Truncated Supply Elasticity in the AI Infrastructure Buildout

Copper prices rose 56 percent above their 2024 average within two years while the refined market recorded a surplus in 2025 and never departed meaningfully from balance. This paper reconciles that pattern with a market-clearing model in which the binding constraint is not the cur...

Active Traversal and Load-Bearing Dependency II (ATLD 2): Residual Coordinate Identification and Self-Auditing Matched-Control Evaluation for Long-Horizon AI Systems

Active Traversal and Load-Bearing Dependency (ATLD) v1.0 introduced a matched-control protocol for testing whether meaningful typed dependency architecture and active recursive traversal contribute causal functional gain beyond the same content presented through flat, isolated, s...

Local Uniqueness of the Born Rule on Categories with Complex-Weighted Morphisms

I prove a local uniqueness theorem for the Born rule in the setting of quiver-generated categories equipped with complex morphism weights and path-amplitude probability functionals. Given (i) non-negativity, (ii) polynomiality of bounded total degree, (iii) global U (1) invarianc...

Two-Copy Onset of Strict Superadditivity for Measured Relative Entropy

For faithful finite-dimensional state pairs, globally optimized measured relative entropy is additive at any fixed copy number n >= 2 exactly when the states commute. This Letter proves the criterion through an explicit phase-optimized two-copy ascent direction, separates coheren...

Oral Immunization with YncE-Encapsulated Chitosan Nanoparticles Confers Protective Immunity against Enterotoxigenic Escherichia coli (ETEC) in a BALB/c Murine Model.

Background: Every year, a large number of people worldwide suffer from gastrointestinal diseases such as diarrhea. Among this population, children under five are particularly vulnerable and are at increased risk of death or malnutrition. Enterotoxigenic Escherichia coli (ETEC) is...