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The cover image is based on the article A Self‐Correcting Adaptive Remeshing Strategy for Three‐Dimensional Phase‐Field Fracture Simulation by FengYu Cheng et al., https://doi.org/10.1002/nme.70402 . image

The two-component system ColRS discriminates metal signals to regulate virulence and resistance in Pseudomonas aeruginosa

Two-component systems (TCSs) in Pseudomonas aeruginosa are essential for sensing and responding to diverse environmental cues, including those associated with ion homeostasis and virulence within the host. However, how specific TCSs discriminate between chemically similar metal s...

Multi-year Assessment of Smolt Migrations in a Large, Fragmented River : Hydropower and the Remnant Wild Atlantic Salmon (Salmo salar) of the River Dalälven

Anthropogenic river modifications can impede diadromous fish migration and passage success. We investigated downstream passage probabilities, migration speeds, and route selection of wild Atlantic salmon smolts in the lower 28 km of the river Dalälven, Sweden, where two hydroelec...

Analysis of sex-specific stroke risk factors in middle-aged and elderly Chinese population based on machine learning approach

Stroke is a leading cause of global mortality and disability, yet comprehensive sex-specific stroke predictors are lacking. This study aimed to identify sex-specific stroke risk factors in middle-aged and elderly Chinese to improve early detection. 12,975 participants (7079 femal...

Adaptable weaving origami

As intelligence continues to deepen in engineering fields, adaptable shape-morphing structures face increasing demands for multifunctionality and reconfigurability. Origami has been widely explored in deployable structures, mechanical computing, metamaterials, and metamorphic rob...

Jomon Division 2

Example The author considers 4 / 2 = 2. Four represents the number of the points. Two represents the number of the first timepoints. Another two represents the number of points per first timepoint. 1. The four points and the first two timepoints exist. 2. The author makes one tim...

The Forcing Factors That Predict Obesity: A Cross‐Sectional Multilevel Machine Learning Model of US County‐Level Prevalence

OBJECTIVE: Variables predicting obesity are not limited to individual-level risk factors. The purpose of this study is to assess multilevel predictors of obesity prevalence. METHODS: US county-level datasets incorporating 34 variables were analyzed cross-sectionally using explain...

Development and validation of a nomogram for predicting 28-day mortality in patients with severe community-acquired pneumonia

Severe community-acquired pneumonia (SCAP) progresses rapidly, is associated with poor prognosis. Early assessment and timely intervention are crucial for improving the short-term outcomes of patients this study aims to develop and validate a Nomogram prognostic prediction model...

A Case Report of Horner’s Syndrome in Labour Neuroaxial Analgesia: Diagnosis, Management and Follow-Up

Background and Clinical Significance: Horner’s syndrome is an uncommon but recognised complication of neuroaxial analgesia in obstetric procedures, with an incidence of 0.4–4%. Case Presentation: This case report describes a 28-year-old primigravida who developed unilateral Horne...

Assessing and advancing the role of health economics in costing climate extremes

The full abstract for this thesis is available in the body of the thesis, and will be available when the embargo expires.

Musical Feature Processing and Learning Difficulties in Greek School-Aged Children: Piloting of a Screening Tool for Amusia

Background/Objectives: The present study aimed to describe a novel screening test for amusia and compare test performance between Greek children with learning difficulties and typical school-aged children. Additionally, it examined whether variables such as sex, age, and formal m...

On the productivity of length-based alternations in Xhosa noun class prefixes

Noun classes in isiXhosa are each associated with specific prefixes on the noun stem. Some of these noun class prefixes exhibit length-based allomorphy: they take one form before multisyllabic stems and a different, longer form before stems that are monosyllabic. Specifically, cl...

Gene Expression of TGF-β1 , Matrix Metalloproteinases, and Collagen in Keloid Patients and Their Growth Patterns in 2D and 3D Cell Cultures: An In Vitro Study

Background/Aim: Keloids result from abnormal wound healing and are characterized by excess fibroblast activity, extracellular matrix (ECM) accumulation, and elevated collagen types. The contemporary research often relies on 2D cell cultures, which do not fully replicate keloid pa...

Mapping spatiotemporal soil temperature using physics-informed neural networks with the heat transfer equation

Soil temperature (ST) plays a critical role in regulating biogeochemical processes in soils, yet its spatiotemporal mapping remains a challenge. Existing ST maps are largely derived from land-surface models and are typically available only at coarse spatial resolutions, limiting...

RLE theory

We present the Recursive Light Emergence (RLE) theory as a unified framework for gravity and quantum mechanics. We propose that spacetime and mass are not fundamental but emerge from the recursive self-interaction of a single photon field. The Einstein field equations are recover...

Implementation of a Laboratory-Integrated Clinical Decision Support System for CKD Screening and Progression Detection in Primary Care

Background: CKD remains substantially underdiagnosed and inadequately monitored. Objectives: To evaluate whether a laboratory-integrated CDSS enables opportunistic CKD detection and longitudinal surveillance in Primary Care via automated KDIGO stratification and progression detec...

The Global Maximum Point Invariance Theorem: A Statistical Invariant Theory of Structural Break Detection — Unified Shape Function, Standardized Limits, and Multi-Regime Generalization

This paper establishes a mathematical theorem system for between-group regression difference statistics in structural break detection. The central result is the Global Maximum Point Invariance Theorem: in a two-regime linear switching model with homogeneous second-moment design,...

Energy storage for power applications: Volumetric comparison of commercial 18650 storage technologies

This paper presents an experimentally grounded volumetric benchmark of selected commercial energy-storage devices in, or close to, the standard 18650 format. The investigated set includes commercially available Lithium-Ion batteries (LIB), Sodium-Ion batteries (SIB), Hybrid Super...

Identification of differential topologically associating domains from low sequencing depth and pseudo-bulk chromatin contact maps

Topologically associating domains (TADs) are fundamental units of 3D genome architecture that shape gene regulation. Comparative analyses of TADs across biological conditions have revealed their involvement in development and disease. However, accurately identifying differential...

Simple birth-death-mutation models predict some—but not all—aspects of the experimental evolution of antibiotic resistance

Mathematical modelling of antibiotic resistance plays an important role in understanding the mechanisms of resistance emergence and spreading, testing the feasibility of new treatment protocols, and antimicrobial stewardship. However, many assumptions underlying some of the most...