Research works

Current and future habitat suitability of Moringa stenopetala (Bak.f.) Cuf. (Moringaceae) in Ethiopia under climate change: implications for agroforestry and investment planning

Moringa stenopetala is an important multipurpose tree recognized for its nutritional, medicinal, and socioeconomic value. Although widely utilized by communities in southern Ethiopia, the species remains underutilized and has a relatively restricted natural distribution, occurrin...

KINOTECA: A Navigator of Chemical Datasets with Reported Kinase Inhibitory Activity

Protein kinases are the most intensively targeted protein family for small-molecule drugs, and the large volume of inhibitory-assay data reported for them makes the family particularly well suited to data-driven and machine-learning approaches to drug discovery. This data, howeve...

Clinical characteristics and functional determinants of central sensitization in chronic neck myofascial pain syndrome

Background Central sensitization (CS) is a key mechanism in chronic pain, but its relationship with cervical muscle pressure pain thresholds (PPT) and disability in myofascial pain syndrome (MPS) remains unclear. Objective To investigate the clinical characteristics and functiona...

EuroMillions Breakthrough Mining — 3309 Sources, 28671 Leads Extracted — E8 Intelligence Research

Mined 3309 lottery+quantum breakthroughs. Extracted 28671 leads across 13 categories. 26299 high-value leads found. Categories: {"CORRIDOR": 2441, "FORMULA": 2267, "GEOMETRIC": 939, "FORWARD_ATTEMPT": 2591, "QUANTUM": 2813, "TIMING": 293, "CELESTIAL": 2352, "GEMATRIA": 2479, "CON...

Phage vB_KpnM_NB cocktail synergizing with amikacin in inhibiting persister cells of Klebsiella pneumoniae

ABSTRACT The emergence of multidrug-resistant Klebsiella pneumoniae (KPN) and antibiotic-tolerant persister cells poses a significant challenge to existing anti-infection therapies. Given the urgent need for sustainable alternatives to antibiotics, phage cocktails are emerging as...

Beyond Using AI : Self‐Regulated Pathways to Engagement in AI ‐Assisted Language Learning

ABSTRACT Artificial intelligence (AI) has increasingly reshaped language learning, yet how learners become engaged in AI‐assisted language learning remains insufficiently understood. Drawing on self‐regulated learning theory, this study examined the relationships among AI literac...

Cancer-associated fibroblasts-derived CAV1 promotes epithelial-mesenchymal transition and stemness in bladder cancer through activation of the LIF/STAT3 signaling pathway

Background Cancer-associated fibroblasts (CAFs) are key components of the bladder cancer microenvironment, but how specific CAF subpopulations drive malignant progression remains unclear. This study aimed to identify CAF driver genes and elucidate the role of caveolin-1 (CAV1) in...

Molecular Identification of Tilapia Using Mitochondrial COI DNA Barcoding from Major Freshwater Reservoirs of Akola District, Maharashtra, India

Abstract Accurate identification of tilapia species is essential for fisheries management, biodiversity conservation and invasive fish population monitoring. Oreochromis species can be difficult to differentiate morphologically because of phenotypic plasticity and overlapping mor...

Distribution domain health descriptor fusion for robust battery state of health estimation

Robust state of health estimation of lithium-ion batteries requires health descriptors that are insensitive to transient signal fluctuations while remaining sensitive to degradation evolution. To this end, this study proposes a distribution-domain health descriptor fusion framewo...

Facebook as a Lifeboat: An Interview Study Exploring the Role of Facebook in Supporting Parents of Children with Rare Diseases

Parents of children with rare diseases face unique challenges due to scarce medical expertise and limited information sources. Social media, particularly Facebook, have become a vital (and sometimes the only) space for parents to access information, share experiences, and find em...

Causative alternation in Tibetic and Trans‑Himalayan

Abstract The article revisits the causative voicing alternation attested in a restricted number of fossilised lexical pairs in various sub-branches of the Trans-Himalayan language family. I introduce linguistic facts from the Tibetic languages which have not been previously inves...

Exploring green talent management in Indian information technology industry: unpacking the mediating role of employee skills in shaping talent outcomes

Purpose The organizations are developing green talents for various roles to meet sustainability targets driven by government regulations and top corporate leaders. The adoption of green talent management (GTM) within the Indian Information Technology firms is limited. This study...

TASA: A Tick-Based Affective State Architecture for Persistent, Inspectable Inner State – Framework, Learnability Conditions, Governance, and Evaluation

Standard language-model inference lacks cross-exchange internal organization. External memory can reconstruct continuity without persistent state whose causal role is tested. We present TASA (Tick-Based Affective State Architecture), a theoretical framework for such a state: segm...

Extracorporeal CO2 elimination for acute exacerbation of severe COPD requiring invasive mechanical ventilation: a randomized controlled trial (the X-COPD trial)

Abstract Rationale Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) requiring invasive mechanical ventilation (IMV) are associated with high mortality and long-term disability. Extracorporeal CO₂ removal (ECCO₂R) using modern high-capacity devices may facili...

The Ameliorative Effects of Leaf Extract of Senna occidentalis on Cannabis sativa-Induced Lung and Renal Damages in Adults Male Wistar Rats

Background: Respiratory diseases remain a major public health concern worldwide while its burden has increased considerably due to environmental pollution, occupational hazards, smoking and substance abuse. Cannabis sativa, has increasingly been associated with respiratory health...

Development and validation of the Pediatric Autoimmune encephalitis Severity Scale in children with autoimmune encephalitis

Autoimmune encephalitis is a rare condition in children in which the body's immune system mistakenly attacks the brain, leading to problems such as seizures, changes in behavior, agitation, memory loss, excessive movements, and, in some cases, a total loss of awareness. Doctors n...

Engineering a dimeric porcine deltacoronavirus S-RBD subunit vaccine for enhanced immunogenicity and neutralizing antibody responses

Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that has caused global epidemics and substantial economic losses, posing a potential risk of cross-species transmission, including to humans. However, commercial vaccines are currently scarce. The receptor...

E8 Coxeter Soliton Train — 30 Topologically Protected Temporal Solitons — E8 Intelligence Research

The 240 E8 root vectors project onto the Coxeter plane as 30 rays of 8 roots each, inheriting the lattice's 30-fold rotational symmetry. When each root carries its φ-scaled 132 Hz harmonic (φ^k·132 Hz), the eight roots on a single ray phase-lock into a coherent temporal soliton t...

Comparative Genomic Analysis of Clonal Variants of a Spirabiliibacterium Lineage Recovered from a Chicken in the United States

The family Pasteurellaceae includes pathogenic and opportunistic bacteria affecting poultry, yet taxonomic resolution remains challenging due to phenotypic heterogeneity, limited genomic representation, and the poor performance of routine diagnostic systems for uncommon taxa. At...

Bayesian Descriptions are not Mechanisms: Predictive Processing and the Realisation Gap in Embodied Neural Dynamics

Abstract Predictive processing casts perception, action, and learning as probabilistic inference. This paper asks when a Bayesian description identifies a mechanism. I distinguish computational description, algorithm, and physical implementation. Mechanism requires a causal mappi...