Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
142111 work(s)
- AI & ComputingOpen access
A single-qubit Ramsey or T2 measurement reports how much interference survives on a qubit, but not why the rest is missing. Phase information lost to an unobserved environment and phase information coherently redistributed into neighbouring qubits produce the same local signature...
- BiologyOpen access
ABSTRACT In bacteria, the auxiliary complex SecDF–YajC participates in the Sec system, facilitating post-translational translocation of preproteins across the membrane through the SecYEG channel. Although YajC homologs are strongly conserved in rhizobial strains and may play impo...
- Health & MedicineOpen access
The Combined Positive Score (CPS) algorithm is used with PD-L1 IHC 22C3 pharmDx to evaluate PD-L1 expression in certain tumor types and determine patient eligibility at defined cutoffs for treatment with KEYTRUDA®(pembrolizumab). The CPS is scored by evaluating the amount of tumo...
- BiologyOpen access
Oncogenic KRAS mutations (G12D/G13D) drive metabolic reprogramming in colorectal cancer (CRC), yet targetable downstream effectors remain poorly defined. Here, we identify enolase-phosphatase 1 (ENOPH1) as an essential transducer directly upregulated by the KRAS–MEK–ERK axis. ENO...
- BiologyOpen access
ABSTRACT The MprBA two-component system (TCS) plays a critical role in Mycobacterium tuberculosis persistence and forms a signaling pathway with the alternative sigma factors SigE and SigB. Here, we demonstrate that the MprBA-SigE–SigB signaling pathway is activated in Mycobacter...
- Engineering & TechnologyOpen access
Beyond Bulk Grade: Mineral–Flow Accessibility at the Pore Scale This release provides the code, analysis products, and reproducibility materials supporting the manuscript: Chakrawal et al., Beyond Bulk Grade: Mineral–Flow Accessibility Controls Pore-Scale Copper Recovery. Critica...
- Health & MedicineOpen access
FBMN-Guided Discovery of Cyanogrisides from Mutant Strain CRM005 and Structural Diversification
Abstract Through genome mining and metabolomic analysis of the mutant strain CRM005, combined with feature-based molecular networking (FBMN) deduplication, five novel natural cyanogrisides (1–5) were selectively isolated and characterized, alongside six previously reported analog...
- Health & MedicineOpen access
Background/Objectives: Seasonal influenza vaccines have been developed to reduce the risk of severe complications in older adults, who are at increased risk of influenza-related morbidity and mortality. This study aimed to synthesize the available evidence on the comparative effe...
- Society & EconomicsOpen access
The loss of protective structures exposes cave temples to climatic disturbances, but the environmental effects of their restoration remain insufficiently quantified. This study develops an environmental-resilience-oriented restoration framework integrating historical reconstructi...
- Materials & Energy
NiCo 2 O 4 thin films were fabricated on SS‐304 substrates using a cost‐effective CBD method by varying the deposition time (3, 4, and 5 h) to regulate the thickness and porosity. XRD confirmed the formation of phase‐pure polycrystalline spinel NiCo 2 O 4 with no detectable secon...
- Society & EconomicsOpen access
Background In August 2026, the English Premier League (EPL) banned front-of-shirt gambling sponsorships to reduce gambling marketing exposure. Shirt sponsorship represents one aspect of broader commercial relationships between football clubs and gambling companies, often not cove...
- Society & EconomicsOpen access
FINDING: Consciousness research remains at the descriptive stage — no quantitative law or invariant has emerged; the only mathematically tractable lead is the "synaptic clock" hypothesis, which posits a minimal temporal duration for conscious content. | MATH: No equations, consta...
- Society & EconomicsOpen access
Uganda ranks third with the highest malaria cases globally, highlighting limitations in existing prevention efforts. Malaria vaccination is a key promising strategy to reduce both morbidity and severity among children under 5 (U5) years. In April 2025, Uganda introduced a four-do...
- Health & MedicineOpen access
Prior systematic reviews suggest that berberine may match or exceed the effects of metformin on metabolic and hormonal outcomes in polyendocrine metabolic ovarian syndrome (PMOS; previously referred to as polycystic ovary syndrome). This review aimed to assess the reported effica...
- Biology
Abstract Mitochondrial DNA (mtDNA) transcription is an emerging target in cancer therapy. While enzyme-targeted inhibitors like IMT1B block POLRMT, their organelle specificity remains unclear. Here, we report a distinct strategy using mitochondria-accumulating nonplanar perylene...
- Society & Economics
Relative height and vertical status in buildings
Abstract Motivated by research that associates higher positioning with well‐being, we expand the vertical price‐gradient literature by estimating the value of within‐ and between‐building “vertical status”: one's relative vertical position compared to others in the same building...
- Health & MedicineOpen access
E8 Chirality Phase-Lock Predicts Anesthesia Emergence Timing — E8 Intelligence Research
Anesthetic-induced unconsciousness and recovery follows a quantized phi-ladder timescale governed by E8 chirality decoherence: emergence occurs at predictable multiples of the 132Hz × φ^n harmonic (1.4s, 2.3s, 3.7s, 6.0s...). Because anesthetic molecules disrupt Weyl orbit alignm...
- Health & MedicineOpen access
Background Mask ventilation is a cornerstone of airway management during general anesthesia, yet the need for airway adjuncts during mask ventilation remains poorly predicted by current preoperative assessments. We aimed to identify independent clinical predictors of this outcome...
- Climate & EnvironmentOpen access
This study assesses the integrated sustainability performance of waste-to-energy (WtE) technology pathways across eight of South Africa’s metropolitan municipalities, which are home to 40.14% of the country’s population. The assessment considers energy generation, GHG emission-re...
- AI & ComputingOpen access
A μ^{9/2} log μ upper bound for windowed Weil forms
Let λmin(λ) be the bottom of the spectrum of Weil's quadratic form restricted to test functions supported in the multiplicative window [λ−1,λ], and put μ=λ2. By Weil's criterion, the Riemann Hypothesis is equivalent to λmin(λ) ≥ 0 for all λ. In previous papers we proved, without...