Research works

Risk and protective factors for the intergenerational transmission of child maltreatment in South Korea: a secondary analysis of data from the Family with Children’s Life Experience Survey

PURPOSE: This study aimed to identify ecological risk and protective factors associated with membership in latent classes characterized by heterogeneous associations between parental adverse childhood experiences (ACEs) and the intergenerational transmission of child maltreatment...

RAS inhibition limits oncogenic signaling and tumorigenesis in neuroblastoma regardless of RAS mutational status

Abstract Neuroblastoma (NBL) is a rare and aggressive pediatric malignancy with a 5-year survival rate of 40–50% for patients diagnosed with high-risk disease. NBLs arise in the sympathetic nervous system and causes 11% of all pediatric cancer deaths. MYCN amplification or overex...

L2K-ARG

Abstract The present study introduces an open-access corpus of Korean second language argumentative writing (L2K-ARG) produced by university-level learners with different first-language backgrounds. The corpus contains 484 essays written in response to three standardized prompts...

Ribo-ITP enables identification of translons from limited input samples

In the last decade, an unexpectedly large number of translated regions (translons) have been discovered using ribosome profiling and proteomics. Translons can act as regulatory elements or encode functional micropeptides. However, identification of translons has been limited to c...

Energy Shocks, Sovereign Capital Structure, and Impacts on Blue Economy Investment", "Managing Sovereign Debt under Energy Shocks: Fiscal Stability and Policy Intervention

Global energy shocks have become a significant challenge for governments by increasing fiscal pressure and affecting sovereign debt sustainability. Fluctuations in oil, natural gas, and electricity prices influence inflation, government revenues, public expenditure, and economic...

Uncovering the scale and link of two SARS-CoV-2 outbreaks in nursing homes by combining integrated genomic surveillance, contact tracing, and point-of-care testing

Abstract Aim The local public health authority (LPHA) in Duesseldorf received notification of two SARS-CoV-2 outbreaks in nursing home A and nursing home B in October 2021 and embarked on an outbreak investitation to identify the source of the outbreak and epidemiological links b...

The effect of Midwifery continuity of care on maternal outcomes among women with psychosocial risk factors in Sweden: A registry-based cohort study

BACKGROUND: Women identified with psychosocial risk factors are at higher risk of interventions during labour and birth and adverse maternal outcomes. Midwifery Continuity of Care (MCoC) reduces interventions and improves maternal outcomes among low-risk women; however, evidence...

Understanding and Applying Useful Instruments to Evaluate Bipolar Spectrum Disorder

Bipolar disorder, a chronic and recurrent psychiatric illness, is characterized by substantial diagnostic challenges and heterogeneous clinical manifestations.Because patients often present during depressive episodes and may not recognize previous hypomanic symptoms, standardized...

Query-Relative Soundness of Legal-Reply Compression in Shogi : Quotient Criteria, Canonical Repair, and Action-Edge Counterexamples

Compressing a finite set of legal Shogi replies into coarse classes can reduce the amount of downstream checking, but such compression is meaningful only relative to what is being asked about those replies. We formalize this point as a query-relative quotient condition. For a pos...

Mechanistic insights, clinical significance, and management strategies for postgastrectomy hypoglycemia in gastric cancer patients in the era of continuous glucose monitoring: a narrative review

Purpose: Postgastrectomy hypoglycemia (PGH) is increasingly recognized as a potential metabolic complication after gastrectomy for gastric cancer. This narrative review summarizes its clinical relevance, underlying mechanisms, and management strategies in the era of continuous gl...

Multi-Layered Electrospun Scaffold Design Strategies Targeting Osteosarcopenia

Osteosarcopenia, the concurrent deterioration of bone density and skeletal muscle mass and function, represents a growing clinical challenge in ageing populations worldwide. Conventional single-tissue therapeutic approaches fail to address the intricate biochemical and mechanical...

Glomerular hyperfiltration in dipstick-negative type 2 diabetes mellitus: a novel determinant of kidney function decline in type 2 diabetes mellitus

Background: The independent impact of type 2 diabetes mellitus (T2DM) on kidney outcomes beyond albuminuria remains unclear. We evaluated whether T2DM affects kidney outcomes in individuals with normal kidney function without albuminuria. Methods: Data from the National Health In...

Strain-release photocatalytic access to rigidified isosteres of bicyclic heterocycles

We present the synthesis of fused isoxazolidine-pyrrolidine architectures via a dual rigidification strategy. These frameworks are accessed through an atom-economical approach using variously substituted isoxazolines and bicyclo[1.1.0]butane (BCB) derivatives under mild condition...

Explainable ensemble machine learning for dissolved oxygen prediction in a reservoir using SHAP and chord diagram analysis

Dissolved oxygen (DO) is a key indicator of reservoir water quality and ecosystem integrity. The dynamics of DO are governed by complex physical, chemical, and biological reactions such as thermal stratification, nutrient interactions, photosynthesis, respiration, and microbial d...

Plants, soil, and coexistence: an alternative approach to modelling plant-soil feedback

Abstract Background and Aims Plant-soil feedback (PSF) affects plant coexistence and diversity. Although the current paradigm provides a direct experimental method to quantify PSF and explains coexistence with varying levels of success, the emphasis on pairwise interactions hinde...

Implementation strategies and adjunctive interventions for HIV testing and linkage-to-care in the United States: a systematic review

Ending the HIV Epidemic in the United States depends on expanding HIV testing and rapidly linking people to care. However, methods to improve testing and linkage-to-care are inconsistently described and often conflate health system–level implementation strategies with recipient-d...

Role of sodium hypophosphite on morphology and corrosion resistance of Ni-P coated Nd-Fe-B

Uniform and dense electroless nickel (EN) was recognized as a promising protective coating for Nd-Fe-B magnets. However, large potential difference between intergranular phase and main phase of Nd-Fe-B made the deposition of EN coating uncontrollable. Sodium hypophosphite was use...

From 5Cs to ABC: operationalizing the AAP guidelines into the MEPA-ABC scale for parental mediation of children’s digital media use

Parental regulation of children’s digital media use is central to healthy development, yet existing instruments are often lengthy or only loosely aligned with contemporary clinical frameworks. The American Academy of Pediatrics (AAP) formulated the 5Cs of Media Use (Child, Conten...

Field evaluation of Pix4D viDoc for retaining wall inspections

Reliably accurate documentation of retaining wall conditions is necessary for managing long-term infrastructure health and maintaining public safety. Current visual inspection practices lack the precision and consistency needed to detect early signs of change in a structure. This...

Antidepressant Use During Pregnancy: An Evidence-based Review of Risk–Benefit Balance and Drug-specific Considerations

Antenatal depression affects approximately 12% of pregnancies, and antidepressant exposure during pregnancy-predominantly selective serotonin reuptake inhibitors (SSRIs)-is estimated at approximately 3% of pregnancies in multinational estimates.Clinical decision-making requires b...