Research works

Genetic screening identifies WNT5A/RYK as a determinant of extracellular vesicle fate

Extracellular vesicles (EVs) are natural mediators of intercellular communication through the transfer of cytoplasmic material from donor to recipient cells. The molecular mechanisms governing EV uptake and cargo delivery in recipient cells remain largely elusive. To address this...

Professional Identity and Education for Sustainability: Exploring Perceived Change Following Service-Learning in Pre-Service Primary Teacher Education

Training educators to integrate sustainability into their practice is crucial for the 2030 Agenda. This article presents a mixed-method design to explore perceived changes in sustainability-oriented professional identity among pre-service primary teachers following a Service-Lear...

Additive Manufacturing of Structural Components for PocketQube-Class Satellites: A Systematic Review of Materials, Processes, Qualification Pathways, and ECSS Compliance

PocketQube-class satellites have emerged as a cost-effective platform for space access; however, their extreme mass, volume, and dimensional constraints challenge conventional manufacturing approaches. This systematic review examines the state of the art of additive manufacturing...

Light and Acid‐Base Dual‐Regulated Atom Transfer Radical Polymerization With ppb Concentrations of Zwitterionic Photocatalysts

ABSTRACT Here, we introduce highly efficient, and acid/base‐responsive zwitterionic photocatalysts (PC) for photoinduced atom transfer radical polymerization (photoATRP). The electron‐withdrawing methylpyridinium substituent enhances the acidity of benzimidazole/naphthoimidazole,...

Beyond the Illegalities: The Silenced Roles of Border Residents in Enhancing Border Security in Ghana

Border residents in the African region have long been portrayed as threats to national security and labelled as passive dwellers or collaborators in cross-border crime. In this study, we apply an Integrated Border Management (IBM) model, supported by labelling theory, to examine...

Challenges diagnosing syphilis in antenatal pacific islanders: A case of secondary syphilis

Cases of syphilis are increasing worldwide. Missed diagnosis of syphilis can have serious consequences, particularly in pregnancy. In areas where yaws, a non-sexually transmitted infection due to Treponema pallidum sub-species pertenue ( T. pertenue ) is endemic, the interpretati...

Molecular basis for protection and cross-protection by human antibodies targeting the parainfluenza virus hemagglutinin-neuraminidase protein

ABSTRACT Human parainfluenza viruses (PIVs) are a leading cause of respiratory illness, particularly in vulnerable populations, where infection can lead to severe disease. Despite their clinical impact, there are currently no licensed vaccines or effective antiviral treatments av...

Humidity‐Guided In Situ Polymerization for Controlled Formation of Smooth, Oriented Covalent Organic Framework Films

Efficient, reliable preparation of high-quality films of covalent organic frameworks (COFs) is essential for fully exploring the potential of this class of porous crystalline compounds in, for example, sensing and catalysis. To this end, in situ polymerization on substrates offer...

Imipenem and relebactam pharmacokinetics in peritoneal fluid: microdialysis reveals infection-independent penetration

species. However, data on tissue-site pharmacokinetics are limited. We evaluated the peritoneal penetration of imipenem and relebactam in healthy and infected rats by using microdialysis. The animals received a single intravenous infusion of imipenem (45 mg/kg) and relebactam (22...

Acquired Hemophilia A in an Elderly Patient Receiving Clopidogrel: Drug-Induced or Age-Associated Autoimmunity?

Acquired haemophilia A (AHA) is a rare but potentially life-threatening autoimmune bleeding disorder caused by autoantibodies against factor VIII. Its presentation is often non-specific and can mimic more common causes of bleeding, leading to delayed diagnosis, particularly in el...

The voice of the univers

It is remarkable that the standard cosmological model, established in the 1960s, has remained conceptually unchanged for more than six decades despite the considerable evolution of technologies, observations, and physical theories. This unusual stability highlights the importance...

Resolving the Mystery of Emotions: The Evolutionary Purpose of Emotions

This article establishes in comprehensive detail the evolutionary history, purpose, and function of emotions within the self-interest framework introduced in the companion papers [1,2,3]. Emotions are conceptualized as an ultra-fast subcortical categorization system that originat...

Harmonic Radial Pre-Filtering for Medical Image Classification: An Empirical Study of Tusi-Couple-Derived Sampling on Mammography and Colonoscopy

We study a deterministic, parameter-free pre-processing transform that resamples a 2D image crop into a structured (angle × radius) grid using a phase-delayed harmonic radial sampling scheme derived from the geometry of the Tusi couple, a 13th-century mechanical construction in w...

Typological Constraints on Motion Event Encoding: Path Satellite Usages and the Perspectives of Turkish EFL Learners

This study aims to investigate how Turkish EFL learners encode motion events in English, with a particular focus on path satellites. As Turkish is a verb-framed language and English satellite-framed, Turkish learners of English often struggle with adopting the canonical verbaliza...

Returning to Sports and High-Impact Exercise After Total Hip Arthroplasty: What Should We Be Recommending in 2026?

The total number of total hip arthroplasties performed each year is expected to increase significantly over the coming decades. As a result, an increasing number of young patients are undergoing total hip arthroplasty while similarly, a growing subset of active elderly patients d...

Integrated Molecular Docking and Molecular Dynamics Approaches Reveal Potential Antimicrobial Metabolites from Echinoderms, Holothuria scabra

The rapid emergence of multidrug-resistant microbial pathogens has created an urgent need for new antimicrobial agents. Marine organisms are a rich source of structurally diverse bioactive metabolites with therapeutic potential, and the sea cucumber H. scabra contains numerous se...

EDUCATIONAL ENVIRONMENT AND SOCIAL-EMOTIONAL LEARNING IN PRIMARY SCHOOLS

ABSTRACT: Various approaches are available to teachers for improving Social and Emotional Learning (SEL). The core components of action programs differ in the manner in which they are delivered, such as through explicit lessons, integration into academic subjects, or modification...

Feasibility of a German High-Frequency Neonatal and Pediatric Intensive Care Dataset (AIx-Neo-Guard Dataset): Secondary Data Cohort Study

BACKGROUND: Available information about existing neonatal and pediatric intensive care datasets is scarce. OBJECTIVE: The objective was to evaluate the feasibility of a monocentric high-frequency dataset of neonatal and pediatric intensive care patients in a cohort study. METHODS...

The TUDOK Operator as a Proposed Operational Measurement Layer for the Rome Call for AI Ethics

In 2020, the Rome Call for AI Ethics articulated a shared, human-centred ethical commitment that organizes the development and use of artificial intelligence around three areas of impact-ethics, education, and rights-and six principles: transparency, inclusion, responsibility, im...

The Plasticizing Effect of Choline Dihydrogencitrate on Starch-Based Films

For the first time, choline dihydrogencitrate salt (CCT) was tested as a sole plasticizer for starch-based materials. The effect of CCT content on the physicochemical properties of the obtained films was evaluated. The FTIR and XRD measurements revealed that CCT exhibited the abi...