Research works

A Rare Association: Gliomatosis Peritonei and Giant Mature Cystic Teratoma: A Case Report

Mature cystic teratomas are the most common ovarian germ cell tumors. However, the rare coexistence of mature teratomas with gliomatosis peritonei, a condition characterized by mature glial tissue implantation in the peritoneum, poses significant diagnostic and therapeutic challe...

A Type-I/II Photosensitizer with Cell Death Self-Reporting for Ferroptosis-Potentiated Photodynamic Theranostics against Large Tumors

Abstract Photodynamic therapy (PDT) with ferroptosis induction is a promising antitumor strategy, yet its efficacy is compromised by conventional photosensitizers limited to single-pathway ROS generation, particularly in large tumors. Herein, a series of D−A−D AIE photosensitizer...

Latent versus sensible thermal storage for load-shifting energy management in medium-deep U-type geothermal heat pump systems: A comparative performance analysis

Thermal energy storage can enhance load shifting and extend heat-pump shutdown periods in medium-deep U-type borehole heat exchanger (MDUBHE) heating systems. However, latent and sensible thermal energy storage are commonly evaluated separately, and their differences in heat-supp...

Lipid Burden and Efficacy of Preventive PCI of Vulnerable Atherosclerotic Coronary Plaques: Post Hoc Analysis From the PREVENT Trial

BACKGROUND: Preventive percutaneous coronary intervention (PCI) of non–flow-limiting lesions (fractional flow reserve >0.80) that are high-risk plaques has emerged as a potential strategy to reduce cardiac events. However, identifying which lesions derive the greatest benefit fro...

Forward-Airbase Vulnerability, Asymmetric Drone Saturation, and the Physical-Layer Fragility of Sovereign Semiconductor IP: From RAF Lakenheath to MCAS Iwakuni

Abstract The rapid obsolescence of static perimeter defense under modern kinetic conditions was empirically validated by Ukraine's long-range thermite and FPV drone strikes against dispersed Russian strategic aviation infrastructure, as documented in frontline investigations by T...

Exposure to residential greenness and subsequent risk of common mental disorders among individuals with COVID-19 in South Korea: A nationwide cohort study

Background Residential greenness is considered protective for mental health, but its impact on clinically diagnosed psychiatric disorders following COVID-19 remains unclear. This study investigated the association between residential greenness and risk of common mental disorders...

Catalytic asymmetric dearomatization of (hetero)aromatic frameworks

Abstract Catalytic asymmetric dearomative cycloaddition provides a powerful route to polycyclic chiral frameworks, yet the precise control of selectivity in such cycloadditions remains a formidable challenge. Herein we report a mechanism-guided strategy that harnesses the unique...

Systematic opto-mechanical design approach for meter-long Nano-AKB mirror system at HEPS

A systematic opto-mechanical design approach is developed for a long Nano-AKB mirror system aimed at stable sub-50 nm hard X-ray nanofocusing. The approach integrates deformation–stiffness-balanced mirror clamping, hierarchical precision alignment, and thermomechanical stability...

Predictors of self-rated health in older adults: insights from an anchoring vignettes study

Abstract Self-rated health is one of the most used measures of subjective health in research. At the same time, it presents several methodological challenges. Self-rated health requires individuals to translate their complex, multifaceted health experiences into a single response...

Effects of transcutaneous electrical diaphragmatic stimulation on diaphragmatic function and clinical outcomes in severe chronic obstructive pulmonary disease exacerbations: a randomized controlled trial

Abstract Background Diaphragmatic dysfunction plays a central role in respiratory failure during acute exacerbations of chronic obstructive pulmonary disease (COPD). Transcutaneous electrical diaphragmatic stimulation (TEDS) has emerged as a potential modality to enhance respirat...

Eco infrastructures and memoryscapes: exploring the intersection of sustainability, politics, and commemoration in Bavaria

Infrastructures, understood as tools and processes enabling social phenomena, play a crucial role in memory and commemoration. This paper examines environmental infrastructures shaping the ‘memoryscape’ in Bavaria, Germany. Drawing on approaches from environmental history and lan...

Choosing Not to Eat Meat: What Characterizes Independently Vegetarian Children?

A growing body of research has aimed to map the characteristics of extraordinary altruists-such as those who have donated a kidney to a stranger. However, this research has primarily focused on adults, and we know little about the development of extraordinary altruism. While chil...

Weak Tensor Transfers, Finite Tensor Closure, and Coherence from Restricted Triple Products

Description We construct a finite-exception weak tensor operation for fixed automorphic representations of general linear groups by combining restricted triple-product harmonic analysis with converse-theorem methods. The analytic construction uses the proved affine-$\Psi$ Fourier...

Redefining leptomeningeal metastasis in non–small cell lung cancer: From terminal complication to molecularly managed disease

Leptomeningeal disease (LMD) is one of the most devastating complications of advanced non-small cell lung cancer (NSCLC), historically associated with profound neurologic morbidity and poor survival. Advances in cerebrospinal fluid (CSF)-based diagnostics, improved molecular char...

A holistic QMRA tool to assess current and future health risks from the drinking water production process

ABSTRACT Climate and socioeconomic changes have the potential to impact waterborne pathogens and associated health risks, although the extent of these impacts remains uncertain. Quantitative microbial risk assessment (QMRA) is a widely used method for estimating health risks from...

Mean arterial pressure for children in US emergency department and prehospital settings

Objectives To externally validate previously reported centile curves for the mean arterial pressure (MAP) on paediatric acute care samples; derive centile curves for paediatric MAP in an acute care population and evaluate the association of age-adjusted MAP with prehospital and i...

When is a rigid pelvis–trunk approximation sufficient? An output-specific model-reduction protocol applied to lumbar mobility in multibody biomechanics

This final manuscript revision presents an output-specific computational model-reduction protocol for lumbar mobility in multibody biomechanics. The primary study compares mass-equivalent exact-lock, axial-yaw-only and three-coordinate architectures using ModelicaHumanBodyPArts v...

Reduced Detection of Human Orphan Gene Transcripts in Disease Tissue Relative to Expression- and Detection- Matched Controls

Human orphan genes are poorly annotated and lowly expressed, which makes their behavior in disease difficult to establish. We analyzed paired normal and disease RNA-seq libraries from four cohorts, quantified against a combined reference in which 2190 of 198,507 transcripts are o...

SARIMA-based forecasting of mangrove vegetation indices across India

Abstract Mangrove ecosystems are crucial to the ecological and climatic dynamics of the Asia–Pacific coastline. However, the ability to predict long-term changes is limited, hindering evidence-based resilience and adaptation strategies. The study presents a remote-sensing framewo...

Sartans and Bisartans: Expanding Therapeutic Horizons Through Broad Receptor Interactions and Repurposing Potential

Angiotensin receptor blockers (ARBs), also known as sartans, are a family of highly selective angiotensin II type 1 receptor antagonists commonly prescribed to individuals with hypertension, heart failure, and chronic kidney disease. Additionally, the discovery and facile synthes...