Research works

Quantitative Evaluation of Geographic Atrophy Progression Using Geographic Atrophy Lesion Front Displacement

Purpose: To evaluate the temporal behavior and relative variability of a margin-based metric, lesion front displacement, for quantifying geographic atrophy (GA) progression secondary to age-related macular degeneration and to compare its performance with conventional metrics. Met...

A mitochondria-related 9-gene induced sputum signature for severe asthma: an integrative transcriptomic analysis with external validation

OBJECTIVE: Severe asthma is biologically heterogeneous, and airway-derived biomarkers for disease stratification remain limited. We aimed to identify a mitochondria-related induced sputum transcriptomic signature associated with severe asthma. METHODS: Two public induced sputum m...

Are We Making It Up? The Forced Intention

Are We Making It Up? The Forced Intention answers the two questions every disclosure-based ontology is asked, and answers them with a single argument: did the inquiry make up its answer — tune its intuitions until something confirmed them — and, prior to that, did it make up its...

TRENDS in Pediatric Palliative Care Research (TPPCR) 2026; Issue #08, Commentary on Katz et al. and Szabat et al.

This TPPCR commentary discusses the 2026 papers by Katz et al., Shifting sands: How parents engage with the idea of their child’s death, in the Journal of Palliative and Supportive Care and Szabat et al., Parental hope in paediatric palliative care: a systematic review of the eth...

'Sea Sparkle' - Simulator of bioluminescent red Noctiluca blooms

This record includes English and Spanish versions of the following files: QuickStart - PDF guide to downloading and installing the Powersim Studio Cockpit application (if not already installed on your PC) Sea Sparkle Simulator - This simulator enables you to investigate how bloom...

A Structural Response to "Microsoft Enterprise AI Delivery": Reviewing Microsoft — StratoAtlas CDSA Diagnostic

A structural stress-test, not a rebuttal, of the StratoAtlas brief "Microsoft Enterprise AI Delivery," applying the CDSA method (Tension → Mechanism → Test → Falsifier) to separate the brief's load-bearing claims from its inferred ones. The review confirms the brief's central and...

From Sequence to an Auditable Fold: Smithian Fold Theory V3 Protein Fold Computational Proof — Preliminary Results

From Sequence to an Auditable Fold, version 0.9.3, is the first standalone preliminary-results release from the Smithian Fold Theory V3 Protein Fold computational proof programme. It reports a target-free exact representation, complete interaction custody, a six-axis joint physic...

MODEL ADOPTION #397: REJECT — LEDGER BENCH: Apply filter: Quarterly phase = DISTRIBUTION — improves win rate from 32.4% — E8 Intelligence Research

DECISION: REJECT ELEMENT: The "Quarterly phase = DISTRIBUTION" filter is not a concrete, testable edge compatible with E8 geometry timing. It relies on an external macro-phase classification (likely derived from a calendar or market cycle model) that is not defined within the E8-...

Metal–Organic Frameworks in Food Biotechnology: Opportunities, Challenges, and Future Perspectives for Probiotic Delivery, Precision Fermentation, and Circular Food Systems

Metal–organic frameworks (MOFs) have emerged as a versatile class of porous nanomaterials with exceptional surface area, tunable pore architectures, and customizable chemical functionalities, creating new opportunities for advanced food applications. Increasing demand for functio...

Fecal carriage of ESBL and Carbapenemase-producing Enterobacteriaceae, and its associated factors among hospital and non-hospital janitors at the University of Gondar, Northwest Ethiopia: A comparative cross-sectional study

Background Extended-spectrum beta-lactamase (ESBL) and carbapenemase-producing Enterobacteriaceae (CPE) pose a critical public health threat. Janitors are routinely exposed to contaminated environments and may act as a reservoir for these resistant bacteria, particularly in resou...

Modality as a Tool for Power Struggle

Edward Albee’s The Zoo Story, set in Central Park, captures the intricate dynamics of social power through a chance encounter of two characters: Jerry, a marginalized drifter, and Peter, a complacent middle-class publishing executive. Through an examination of language nuances, t...

A Dynamic Graph–Based Multiobjective Optimization Method for Physician Recommendation: Development and Evaluation Study

Abstract Background Online health care consultation provides patients with broad access to physicians, but also presents the challenge of selecting a suitable doctor in the absence of triage guidance. Patients have multifaceted needs, prioritizing not only recommendation accuracy...

Topkapı Sarayı Müze Kütüphanesindeki R. 432 Numaralı, Nadir Bir Resimli Mesnevî-i Mânevi Nüshası

Bu makale, Mevlânâ Celâleddîn-i Rûmî’nin tasavvuf düşüncesinin temel metinlerinden biri olan Mesnevî-i Manevî’nin, Topkapı Sarayı Kütüphanesi’nde R. 432 numara ile kayıtlı resimli bir nüshasını ayrıntılı biçimde incelemektedir. Mesnevî’nin gerek Anadolu gerek İran coğrafyasında h...

Dynamics of Occupational Well-Being and Turnover Intention in Long-Term Care: A 12-Month Longitudinal Study of Nursing Assistants

Background/Objectives: High turnover intention represents a critical challenge in the long-term care sector, affecting both workforce stability and quality of care. Identifying the psychosocial factors associated with turnover intention and understanding how they operate over tim...

Existence of Solutions for Quasilinear Schrödinger Equations Under Non-Coercive Conditions

In this paper, we study the existence of solutions for a class of quasilinear Schrödinger equations under general potential conditions. The quasilinear term causing the functional to be ill-defined in H1(RN) is addressed via a dual approach involving a change of variables. To ove...

A Cross-Linguistic Cognitive Analysis of ‘Nurturing a Potential Betrayer’ Idioms and Implications for Idiom Teaching

This cross-linguistic cognitive study analyses nine “nurturing a potential betrayer” idioms across eight languages—English, Vietnamese, Chinese, French, Spanish, Arabic, Japanese, and Turkish—while addressing their pedagogical implications for language teaching and learning. Desp...

A multiplex dual-probe RT-LAMP assay for rapid subtype-specific detection of respiratory syncytial virus A and B

Respiratory syncytial virus (RSV) is a leading cause of acute respiratory tract infections, particularly in infants, older adults, and immunocompromised individuals. RSV is classified into two major subtypes, RSV A and RSV B, which co-circulate seasonally and exhibit genetic vari...

Development and Validation of a Scale to Measure Blockchain Awareness and Financial Confidence in the Turkish Financial Sector

This paper seeks to develop an empirically tested theoretical model that measures the block chain related awareness, confidence, and perceived relevance regarding finances among employees in the Turkish financial services sector. From the existing literature on blockchain adoptio...

Toward on-premises RAG pipelines for AI-assisted neuroradiology: practical considerations on privacy, accuracy, and timeliness

Accurate differential diagnosis (DDx) in neuroradiology is challenging and remains vulnerable to cognitive biases and inter-reader variability in clinical practice. Despite expert training, human-generated DDx may be limited in breadth. Large language models (LLMs) have shown pro...

A New Technique for the Treatment of Ureteral Stricture in Patients with Solitary Kidney

OBJECTIVE: To evaluate the safety and efficacy of the Allium metal ureteral stent (AMUS) in treating ureteral stricture (US) in patients with solitary kidney (SK). PATIENTS AND METHODS: We prospectively collected clinical data from 47 SK patients with US who underwent endoscopic...