Research works

PHARMACOLOGICAL POTENTIAL OF LUTEOLIN-7-O-GLUCOSIDE: MOLECULAR MECHANISMS UNDERLYING ITS ANTICANCER, ANTI-INFLAMMATORY, AND NEUROPROTECTIVE ACTIVITIES

Luteolin-7-O-glucoside (LUT-7G), also known as cynaroside, is a naturally occurring flavonoid glycoside widely distributed in medicinal plants and dietary sources. Growing evidence has highlighted its diverse pharmacological activities, including anticancer, anti-inflammatory, an...

RASOUSADHI AS MICRONUTRIENT SUPPLEMENT: AN INTEGRATIVE APPROACH THROUGH DHATU SIDDHANTA

Micronutrient deficiency remains a major global health challenge, with a significant proportion of the population lacking essential nutrients such as iron, zinc, vitamin D, and vitamin B12, despite widespread use of fortified foods and synthetic supplements. Organically derived n...

A REVIEW ON BULK MANUFACTURING IN THE PHARMACEUTICAL INDUSTRY

Bulk pharmaceutical manufacturing, encompassing both active pharmaceutical ingredients (APIs) and large-scale drug product formulation, forms the foundation of the global healthcare supply chain. This review presents a structured overview of modern bulk manufacturing, including s...

ANTIMICROBIAL RESISTANCE AND DRUG DEVELOPMENT

Antimicrobial resistance (AMR) is one of the greatest threats to public health today and puts many of the medical advances of modern times, like effective antibiotics, at risk. Improper and excessive use of antibiotics in medicine, veterinary practice, and farming has given rise...

ARKAKSHIR SHAKHADRAVA EMBEDDED KSHARSUTRA IN THE MANAGEMENT OF MASHAK (MOLE): A CASE SERIES

Background: Mashak (mole/melanocytic nevus) is a benign pigmented skin lesion described in Ayurvedic classics under Kshudra Rogas. Although mostly harmless, moles can cause cosmetic concerns or rarely undergo malignant transformation. Conventional treatments include surgical exci...

UNANI PERSPECTIVE OF PEDIATRIC TUBERCULOSIS (SIL): CLASSICAL MANAGEMENT AND SUPPORTIVE STRATEGIES FOR ATT-INDUCED ADVERSE EFFECTS

Mycobacterium tuberculosis, the cause of tuberculosis (TB), continues to be a serious worldwide health concern, especially for children in high-burden nations. Due to its paucibacillary origin, ambiguous clinical presentation, and challenges with microbiological confirmation, pae...

A CLINICAL STUDY TO EVALUATE THE EFFICACY OF CHANDANADICHURNA ANJANA ALONG WITH SHATAVARYADI CHURNA IN THE MANAGEMENT OF SHUKLA ARMA (NON- PROGRESSIVE PTERYGIUM)

Shukla Arma (Non-progressive Pterygium) is one of the common ocular surface disorders described under Shuklagata Netraroga in Ayurveda. It is characterized by a slow-growing, white fibrovascular tissue extending from the conjunctiva towards the cornea. In modern ophthalmology, no...

VISHGHNA PROPERTY OF GOGHRITA AS VISHGHNA DRAVYA IN AYURVED AND FOLK MEDICINES

Goghrita (Cow’s Ghee) holds a highly revered position among the Chaturvidha Sneha (four types of dietary fats) in Ayurvedic classical literature. Renowned for its unique properties like Samskarasya Anuvartana (the ability to assimilate and amplify the therapeutic attributes of pr...

PHARMACOGNOSTICAL STANDARDIZATION OF HARITAKI (TERMINALIA CHEBULA RETZ.): A MICROSCOPIC STUDY

Background: Haritaki (Terminalia chebula Retz.) is one of the most important medicinal plants described in Ayurveda and is widely used in numerous formulations for its Rasayana, Anulomana, and Tridoshahara properties. The present study was undertaken to evaluate the pharmacognost...

PLASMID PROFILING AND POST-CURING ANTIBIOTIC SUSCEPTIBILITY EVALUATION OF SELECTED MULTIDRUG-RESISTANT SURGICAL SITE INFECTION BACTERIAL ISOLATES

Background: Multidrug-resistant (MDR) bacterial pathogens associated with surgical site infections (SSIs) represent a major therapeutic challenge due to widespread dissemination of plasmid-mediated antimicrobial resistance. Characterizing plasmid profiles and determining the cont...

MATERNAL AND FETAL OUTCOMES IN ANTEPARTUM ECLAMPSIA PATIENTS ADMITTED IN TERTIARY CARE CENTRE: A PROSPECTIVE OBSERVATIONAL STUDY

Background: Antepartum eclampsia is one of the most severe manifestations of hypertensive disorders of pregnancy and remains a major contributor to maternal and perinatal morbidity and mortality, particularly in developing countries. Despite improvements in antenatal surveillance...

FORMULATION AND EVALUATION OF POLYHERBAL FACIAL SCRUB

The Importance of Cosmetics has increased as many people want to stay young and attractive. There are many products available in market regarding skin care and face care. Scrub is one of the products which is used to cure different types of skin conditions, such as acne, aging, r...

UNDERSTANDING SIMAN MUFRIṬ: A UNANI PERSPECTIVE AND THERAPEUTIC APPROACHES

Around the world, obesity is a serious health issue. Obesity adversely affects psychological and social well-being in addition to physical health. Currently, obesity is a major global health concern associated with an increased risk of cardiovascular, metabolic, and musculoskelet...

MACHINE LEARNING IN PHARMACEUTICAL FORMULATION DEVELOPMENT

The use of ML algorithms in pharmaceutical research has enabled remarkable progress, especially by circumventing the problems inherent in the trial and error method of drug development. This review is intended to highlight the growing use of machine learning algorithms such as ar...

CLASSIFICATION OF SNEHA KALPANA - A CRITICAL REVIEW THROUGH BRIHATRAYI

Introduction: Sneha Kalpana is an important and widely practiced dosage form in Ayurveda, with references tracing back to the Vedic period. It is formulated using Kalka, Drava, and Sneha, which facilitate the extraction and delivery of both fat-soluble and water-soluble constitue...

REVIEW OF SECURITY FEATURES IN INDIAN AND FOREIGN BANKNOTES: COMPARATIVE PERSPECTIVES ON FRAUD PREVENTION AND COUNTERFEITING

Currency is the foundation of any state economy, enabling trade, commerce, and financial transactions. With the increasing sophistication of counterfeit currency production due to advanced digital printing and imaging technologies, central banks worldwide have been constantly enh...

A RANDOMIZED OPEN LABELLED CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF MANJISHTHADI TAILA NASYA AND ANU TAILA NASYA ALONG WITH PATHYADI KWATH IN THE MANAGEMENT OF ARDHAVABHEDAKA (MIGRAINE)"

Background: Ardhavabhedaka is one of the eleven Shirorogas described by Acharya Sushruta and is characterized by recurrent unilateral headache associated with severe pain. The clinical presentation closely resembles migraine, one of the most prevalent primary headache disorders w...

EFFICACY OF RITUCHARYA IN THE PREVENTION OF SEASONAL DISEASES: A SYSTEMATIC CRITICAL REVIEW OF CLASSICAL PRESCRIPTIONS AND CONTEMPORARY CLINICAL EVIDENCE

In South Asia, seasonal diseases (respiratory, allergic, gastrointestinal, vector-borne, and dermatological) make up a significant proportion of morbidity and Ritucharya (Ayurvedic seasonal regimen) is said to play a preventive role against these types of diseases, but the eviden...

RARE CASE OF LIVER ABSCESS SECONDARY TO INTRAHEPATIC RUPTURE OF GALLBLADDER & CHOLECYSTOHEPATIC FISTULA COMPLICATING ACUTE CALCULOUS CHOLECYSTITIS IN AN UNCONTROLLED TYPE 2 DIABETIC: A CASE REPORT AND REVIEW OF LITERATURE

Acute calculous cholecystitis rarely progresses to intrahepatic perforation with formation of a giant liver abscess. Such cases are associated with delayed presentation, uncontrolled diabetes mellitus, and significant morbidity. We report the case of a 62-year-old male with poorl...

COMPLETE REGRESSION OF UTERINE FIBROID WITH POLYHERBAL AYURVEDIC INTERVENTION IN A PERIMENOPAUSAL WOMAN: A CASE REPORT

Uterine fibroids are the most common benign pelvic tumours in women, affecting up to 70 -80% of women by the age of 50 and representing a leading indication for hysterectomy. This case report presents the complete ultrasonographic regression of a uterine fibroid following a struc...