Research works

An Intensified Training Period Reduces REM Sleep but this Decline Can Be Mitigated by Ketone Ester Supplementation

Introduction: We previously showed that a strenuous training day disrupts sleep efficiency and REM sleep, and that these disturbances can be counteracted by ketone monoester (R)-3-hydroxybutyl-(R)-3-hydroxybutyrate (KE) supplementation. However, the impact of prolonged intensifie...

Effects of crossing distance on components of fitness in two rare rock plants

Abstract To alleviate negative effects of genetic drift on rare plants, it has been suggested to artificially increase gene flow between isolated populations and create new populations by mixing different provenances to maximize genetic variation. However, there is also a risk of...

Associations Between Self-Care and Hypertension Knowledge, Illness Perceptions, and Depression in Patients With Hypertension

Background: Inadequate self-care among patients with hypertension is associated with uncontrolled blood pressure, increased rates of complications, higher morbidity and mortality, and increased healthcare costs. Identifying factors influencing self-care behaviors is essential for...

Exogenous soluble sugars modulate disease severity and physiological and biochemical responses in olive (Olea europaea L.) trees infected with Verticillium dahliae Kleb.

Verticillium wilt, caused by Verticillium dahliae Kleb., is a soil-borne disease limiting olive ( Olea europaea L.) production, and its management remains challenging. This study evaluated the effects of soluble sugars, applied alone or in combination with fungicide and Trichoder...

Machine-Learning-Driven Dual-Mode Immunoassay Based on Nanobody and Natural Fluorescent Probe for Ultrasensitive Quantification of Pseudomonas aeruginosa

Abstract Pseudomonas aeruginosa is a Gram-negative opportunistic bacterial pathogen posing severe threat to environmental safety and human health. To achieve rapid and accurate detection, we developed a nanobody-based colorimetric-fluorescent dual-mode sandwich immunosensor using...

Use of Tamoxifen Derivatives in Combination with Colistin against Colistin-Resistant Acinetobacter baumannii

Abstract Drug repurposing has led to the identification of tamoxifen, a well-known chemotherapy drug, as a compound with relevant antibacterial properties. In this field, the development of new tamoxifen derivatives with antimicrobial activity, particularly against colistin-resis...

Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature

Positional vertigo is a frequent complaint in otology and vestibular physiotherapy, arising from functional or structural causes affecting the peripheral or central vestibular systems. Although benign paroxysmal positional vertigo (BPPV) is the most common form, other etiologies...

Ethical considerations for intraoperative implementation of artificial intelligence clinical decision support systems: a scoping review

Intraoperative artificial intelligence (AI)-based clinical decision support (CDS) systems are increasingly proposed for surgical decision-making, yet evidence supporting their clinical implementation and ethical governance remains limited. We searched five databases for studies p...

Shared transcriptional consequences of epigenetic machinery disruption in murine neuronal progenitors

The Mendelian disorders of the epigenetic machinery (MDEMs) are an emerging group of disorders which commonly involve disruption of intellect and growth. To investigate consequences of epigenetic machinery (EM) disruption during neurodevelopment, we systematically knocked out (KO...

Gender violence, sport and physical activity: perceptions of sport science students

Abstract Gender-based violence is a problem present in our society, whose perception by university students is essential to understand its impact. The aim of the study was to analyse the perception of students of the Faculty of Sports Sciences and Physical Education of the Univer...

Ethnographic research on digital intimate platforms: a feminist look at ethical and methodological challenges

Ethical and methodological challenges are common in ethnographic research on digital intimate platforms, with which we identify digital platforms designed and used for intimate, sexual, and romantic interactions and encounters. Referring to the eight principles of data feminism f...

Impact of Extent of Surgical Resection on Survival in Patients With High-risk Neuroblastoma

Objective: The impact of extent of resection of the primary tumor on outcomes in patients with high-risk neuroblastoma (HRNB) remains uncertain. We evaluated this issue in patients with HRNB treated on a prospective trial of multimodality therapy. Summary of Background Data: Pati...

Self-Assembling Nanoparticles to Assess Multivalent Interactions between Influenza A Virus Hemagglutinin and Glycan Surfaces

Abstract The multivalent display of surface glycoprotein hemagglutinin (HA) on Influenza A viruses (IAVs) enhances the overall binding avidity to sialylated glycans on host cell surfaces. While precomplexing HA trimers with antibodies increases multivalency and avidity, this meth...

Investigation of polyetheretherketone as secondary crown material with an occlusal gap in double crowns

The use of polyetheretherketone (PEEK) in double crowns has gained increasing attention but the effect of an occlusal gap on various double crown assemblies involving PEEK material has not been thoroughly investigated although it has a critical influence on the retention mechanis...

One-time basal application of urea blended with controlled-release urea increases cotton yield and nitrogen use efficiency by enhancing mid- to late-season soil mineral nitrogen

Abstract Background The one-time combined application of conventional urea (U) with controlled-release urea (CRU), manure (M), or nitrification inhibitors (NIs) offers sustainable nitrogen (N) management options. However, their comparative performance under equivalent N inputs re...

Systemic Onset Juvenile Idiopathic Arthritis (SoJIA) mimicking Incomplete Kawasaki Disease in a 5-year-old

A 5-Year-Old male presented with 9 days of fever, rash, and poorly described muscle/joint pain despite multiple outpatient visits and treatment with antibiotics for presumed streptococcal pharyngitis, and acute otitis media.In the emergency department he appeared ill with cracked...

Parasitic generative AI: how technologies feed on PR professionals' vulnerabilities

Purpose As artificial intelligence (AI), particularly Generative AI (GenAI), has been rapidly adopted in the public relations (PR) industry, it has prompted discussions about opportunities and challenges. Yet, how frontline PR professionals experience such rapid changes and how t...

Δ133p53α, a senescence-inhibitory p53 isoform, attenuates accelerated aging in progeria mice

Abstract Research on progeria not only contributes to the development of treatments for the disease but also enhances our understanding of physiological aging. In a mouse model of Hutchinson-Gilford progeria syndrome (HGPS), transgenic expression of Δ133p53α, a senescence-inhibit...

Sustainable food packaging reinforced by bee-derived bioactives and biopolymers

Abstract The rising preference for eco-friendly food packaging has intensified research on biodegradable materials with enhanced functional performance. Bee-derived bioactives such as beeswax, propolis, honey, and royal jelly have shown significant potential as natural additives...

Two-Stage Method of Manufacturing Passive Conducting Structures by Laser Decomposition of AlN Ceramics

This paper presents a two-stage method for fabricating passive conductive structures of arbitrary geometry on aluminum nitride (AlN) ceramic substrates via laser decomposition using nanosecond pulses of Nd:YAG fiber laser (λ = 1062 nm). We developed a two-stage process which allo...