Research works

Applications of Hopf Solitons in the Global Realism Framework: Interstellar Flight, Interstellar Communication, Interstellar Defense, and Induced Nuclear-Energy Processing

Starting from the foundational manuscripts of the global realism program, we reformulate the present manuscript as a unified application framework for Hopf-soliton physics inside the global-realist ontology. The central thesis is that once matter is treated as a hierarchy of loca...

A 5/4 bound for graphic s-t path TSP on subcubic graphs

We study the graphic s-t path TSP on subcubic graphs (maximum degree 3): given two vertices s, t, find a shortest walk from s to t that visits every vertex. Our main result is that the optimal 5/4 coefficient is attained for every terminal pair — including the difficult case wher...

δ-theory: Self-Reference Depth as a Fundamental Parameter for Matter, Consciousness, and Emergence

This is version 3.4. It records the outcome of an adversarial re-run of every numerical claim in v3.3 against the deposit's own definitions, and it corrects the claims that were found to be stated above what the computation supported. The corrections are recorded in CORRIGENDUM-2...

The Effects of Hurricane Helene on Mental Health and Physical Activity

Introduction: Hurricane Helene brought widespread damage to Southern Appalachia, disrupting utilities, health care, and recreation. While natural disasters are linked to declines in mental and physical health, few studies have examined their effects on distinct types of physical...

Starting with Story, Not Symptom: Narrative Collapse and Cultural Repair in Appalachia

Appalachia's opioid crisis reflects uneven burdens, especially in distressed coalfield counties, and it cannot be solved by symptom tracking alone. This commentary argues for a narrative shift, starting with story and cultural repair alongside clinical care. Narrative collapse is...

An Exact Laplacian-Eigenvalue Degeneracy Between the Spin-½ and Spin-3/2 Representations of 2I

On the binary icosahedral group $2I$ with the canonical generating set $S = 10a \cup 10b$ ($|S|=24$), the spin-$\tfrac{1}{2}$ and spin-$\tfrac{3}{2}$ irreducible representations share the same Cayley-graph Laplacian eigenvalue, $\lambda_{1/2} = \lambda_{3/2} = 18$. The spin-$\tfr...

Physical Irreversibility in Quantum-Geometry Dynamics: Dynamics in Discrete Space as the Origin of the Arrow of Time, the Second Law, the Thermodynamics, the Measurement Problem, and the Limits of Quantum Computing

The fundamental laws of classical mechanics, quantum mechanics, and general relativity are time-symmetric, yet macroscopic experience is irreversible without exception. Standard physics bridges this gap with statistical argument: reversal is treated as merely improbable, not phys...

DFAN: Distributed Fractal Awareness Network — A Biomimetic Control Architecture for Intelligent Energy Transfer Systems

This paper formally defines the Distributed Fractal Awareness Network (DFAN) paradigm as a biomimetic control architecture for energy transfer systems. DFAN treats source-plus-distribution-plus-zones as a living organism, with explicit mappings from biological components (heart,...

Anchor Transfer Learning for Cross-Dataset Drug-Target Affinity Prediction

Drug target affinity models often score well on one benchmark but fail on proteins they have not seen before. We study anchor transfer, a small change to how the prediction is made. Instead of scoring a protein and a drug on their own, the model is also shown an anchor, a second...

Closure of the Constraint Algebra in 1+1D Chrono-Grid Dynamics (Version 2 – corrected)

This preprint presents a consistency check for Chrono‑Grid Dynamics (CGD) in 1+1 dimensions: the closure of the Dirac constraint algebra. Starting from the fermionic representation obtained via the Jordan–Wigner transformation, exact lattice operator identities are derived and ve...

Eosinophilic Esophagitis as the Only Clinical Symptom in a Pediatric Patient: A Case Report

Eosinophilic esophagitis is defined as the presentation of greater than or equal to 15 eosinophils per high-power field on light microscopy after a biopsy. It is a TH2 antigen-mediated response. 1 Typical patient presentation of symptoms is dysphagia, emesis, abdominal pain, regu...

Breaking Solvent Constraints Enables Sustainable Nanoscale Chemical Synthesis by Acoustic Droplet Ejection

This folder contains the Supporting Information–related raw and processed data associated with the publication: “Breaking Solvent Constraints Enables Sustainable Nanoscale Chemical Synthesis by Acoustic Droplet Ejection” The dataset provides full transparency and reproducibility...

Topological Interpretation of XENONnT Low-Energy Anomalies

The XENONnT experiment stands as one of the most precise scientific instruments ever built, having reached unprecedented sensitivity in the direct search for dark matter. While its primary WIMP program has yielded null results, several low-energy anomalies persist in published da...

Before You Begin

For any field, there exists a time after which the minimum knowledge required to contributetakes longer to acquire than a human life allows. I argue this threshold exists given only twoassumptions: that knowledge accumulates, and that humans are finite. I then examine proposedsol...

Community-Based Participatory Research for Critical Health Interventions for the Quichua People in Bolivar, Ecuador

The health needs of rural Ecuadorians are often addressed through foreign aid and short-term medical missions. While these efforts provide temporary relief for rural populations struggling to access government-mandated universal healthcare, they fail to address underlying systemi...

Investigating a Standardized Protocol for Osteopathic Manipulative Treatment of Primary Dysmenorrhea: A Preliminary Single-Blinded Study

Primary dysmenorrhea, characterized by painful uterine contractions during menstruation which affects a large proportion of individuals. Current standard of care is management with non-steroidal anti-inflammatory drugs (NSAIDs). While effective, NSAIDs carry risks with prolonged...

Xylazine Usage and Awareness Among People Who Use Drugs in Denver, Colorado

<b>Background</b>: Xylazine, also known as “tranq,” is an alpha-2 agonist with various effects including central nervous system depression, analgesia, and vasoconstriction. Since xylazine is a non-opioid, its effects are not reversible with ,bnaloxone, complicating overdose treat...

Balancing Optimism and Empathy: Lessons from a Granddaughter and Future Physician

We are fortunate to have a close-knit family, spending every holiday in the same living room, going on annual summer vacations, or camping together. My grandparents had four children and many grandchildren, so we always had big gatherings at their house growing up. Earlier this y...

A standard operating procedure to enable global, regionally-guided precision oncology knowledge bases

Preprint article submitted to a peer-reviewed journal. This version has not yet undergone peer review. Abstract: Precision oncology knowledge bases are central to interpreting cancer genomic variants and associating them with clinical implications, guiding therapeutic selection a...

The Integrated AI Triad (IAT) A Systemic Framework for Redefining the Roles of Teachers, Managers, and Families in the AI Era

The integration of Artificial Intelligence in education requires a systemic restructuring rather than mere tool adoption. This technical report introduces the Integrated AI Triade (IAT), a model that redefines the educational ecosystem by positioning AI as a mediator between thre...