Research works

Sputtered NiCu Thin Films on Nickel Foam for Overall Electrochemical Water Splitting in Alkaline Media

Development of high‐performance and low‐cost electrocatalysts is essential for commercialization of alkaline water electrolysis. The fabrication of nickel‐copper (NiCu) thin films is reported with a Ni:Cu atomic ratio of 3:1, directly deposited onto nickel foam using sputtering....

Applications of double bond indices: Quantitative characterization of properties of benzenoid hydrocarbons

Topological indices (TIs) are widely used descriptors in QSAR/QSPR modeling, but conventional degree-based TIs neglect bond multiplicity, potentially limiting structural resolution. Thirteen extended double-bond-corrected TIs were derived via a Kekuúlé-structure-based edge classi...

Documented Governance Configurations for Proximity-Based Public Cultural Services in Zhejiang, China

Proximity policies specify where services should be reachable, but documented service design does not establish sustained operation. This study compares the policy and governance configurations presented for public cultural services in Jiaxing and Lishui, Zhejiang, China. Operati...

Structural basis for loop-dependent inhibition by AcrIIC1 anti-CRISPR proteins

Most characterized anti-CRISPR proteins act via well-defined core inhibitory mechanisms, yet how auxiliary structural elements modulate and potentiate these canonical processes remains poorly understood. Here, we show that AcrIIC1Boe represses Nme1Cas9 activity through an integra...

Radiation-induced meningioma and high-grade glioma following craniospinal irradiation for medulloblastoma: a case report

Background: Cranial irradiation is known to carry the risk of late intracranial toxicities, most notably the development of secondary intracranial neoplasms. Both meningiomas and gliomas can develop as radiation-induced tumors. Radiation-induced meningiomas represent the most com...

Resilient or unstable? Real rate regimes in emerging markets

Abstract We examine whether real interest rates in emerging markets are uniformly mean-reverting or instead exhibit state-dependent persistence. Using the quantile panel unit root test with common factors on a balanced monthly panel of fourteen emerging economies over 2000–2024,...

Spatial patterns and preservation inequality of socialist built heritage in Beijing: a GIS–geodetector analysis (1915–1978)

Abstract Socialist Built Heritage (SBH) represents a crucial part of China’s modern urban memory, embodying the historical legacy and ideological aspirations of the socialist construction era. Yet, amid rapid urbanisation, SBH faces growing threats from redevelopment and policy n...

Preclinical characterization and first-in-human phase I dose-escalation results with JYB1907, a novel anti-GARP-TGF-β1 complex monoclonal antibody in patients with advanced solid tumors

Transforming growth factor-β1 (TGF-β1) promotes immunosuppression in the tumor microenvironment via the GARP-latent TGF-β1 complex on regulatory T cells. JYB1907 is a humanized IgG4 monoclonal antibody targeting this complex. Preclinically, JYB1907 bound GARP-latent TGF-β1 comple...

Reimagining Bucharest’s Central Station: PPP and Air Rights as Tools for Metropolitan Integration

Railway-station redevelopment is increasingly associated with transit-oriented development, land-value capture, and metropolitan regeneration, yet post-socialist station areas remain insufficiently examined through an integrated spatial, operational, and financing lens. This pape...

The Distributional Consequences of Commodity Booms

This paper examines the response of income inequality to commodity price shocks and identifies the underlying mechanisms at play. I provide novel cross-country evidence from commodity-exporting nations, showing that positive commodity price shocks reduce labor income inequality b...

Contemporary Analysis of the Volume–Outcome Relationship for Patients With Nontraumatic Subarachnoid Hemorrhage

Background Nontraumatic subarachnoid hemorrhage (SAH) carries a substantial mortality burden and risk of long‐term morbidity. Although prior investigations have demonstrated an inverse association between SAH admission volume and in‐hospital mortality, reported thresholds remain...

Missed Opportunities: Toxicology Screening Remains Incomplete Among Firearm-Injured Adolescents

Background Firearm injury remains the leading cause of death among children and adolescents in the United States. Firearm-injured adolescents are at increased risk for substance use and behavioral disorders, yet toxicology testing remains inconsistent despite national recommendat...

A modular in vitro multienzyme cascade for the sustainable synthesis of high-value vidarabine 5′-monophosphate from adenosine

Nucleoside analogues such as vidarabine (Ara-A) are vital therapeutics but are often limited by poor pharmacokinetics. Its phosphorylated form, vidarabine 5′-monophosphate (Ara-AMP), offers improved solubility and is used as a clinical alternative, although it can be dephosphoryl...

Interfacial Effects on the Catalytic Performance of Water-Splitting Electrocatalysts

Electrochemical water splitting is a core component of clean and renewable energy technologies. Developing low-cost, highly active electrocatalysts is critical to enabling its large-scale deployment. Interfacial effects, which govern charge-transfer kinetics and the adsorption of...

Artificial Intelligence in the Assessment of Spasticity and Gait Disorders: A Critical Review of Methods, Sensors, and Clinical Integration

Spasticity and neuromuscular dysfunctions are common consequences of neurological conditions such as cerebral palsy, stroke, traumatic brain injury, and spinal cord lesions, substantially impairing mobility and quality of life. Artificial intelligence (AI) is increasingly employe...

VASP cooperates with zyxin to organize mechanically competent adhesions

Abstract Focal adhesions (FAs) are dynamic macromolecular assemblies that anchor the actin cytoskeleton to the extracellular matrix via integrin receptors, thereby regulating cell morphology and migration. Here, we show that the vasodilator-stimulated phosphoprotein (VASP) cooper...

Interlayer Bonding through Olefin Metathesis in 3D-Printed Poly(dicyclopentadiene) Thermosets

Abstract The direct ink writing (DIW) of thermosetting polymers is fundamentally constrained by weak interlayer bonding, leading to mechanical anisotropy and limiting their use in structural applications. Existing strategies to mitigate this challenge typically rely on thermal po...

Situating abortion: Hindi cinema and the cultural politics of reproductive choice

After gaining independence in 1947, India witnessed a high maternal mortality rate due to unsafe and illegal abortions. As a result, the nation introduced the Medical Termination of Pregnancy Act in 1971, based on the British statute. Despite its progressive provisions, this Act...

New Quality Productive Forces and Pollution–Carbon Reduction Synergy: Evidence from Chinese Manufacturing Firms

Against the background of China simultaneously pursuing the dual strategic goals of “fundamental improvement in ecological environment quality” and “carbon peaking and carbon neutrality,” exploring whether new quality productive forces—as a new engine for high-quality economic de...

Fairness, Trust and Understanding As Preconditions and Predictors for Industry 5.0 AI Adoption

Background Workplace adoption of AI technologies depends, not only on technical performance, but also on whether people perceive these systems as fair, trustworthy, and understandable. Existing research utilises varied definitions for these concepts, impeding our understanding of...