Research works

Reward selectively preserves relational structure in memory

Memories tend to form networks that reflect relationships between experiences. These networks, or cognitive graphs, have been used to study how structural features of memory can bias decisions — analogous to how reward shapes choices by prioritizing reward-associated items in mem...

Performance evaluation of a solar flat plate air heater integrated with Zinc oxide based nano-enhanced phase change materials

This study experimentally explores the thermal energy storage and conversion behaviour of a solar flat plate air heater system (SFPAHS) integrated with ZnO–Ne–PCM. For, this real-time test rigs with paraffin wax (case – I) and with ZnO – Ne – PCMs (case – II) are observed in the...

Technological variability in Etruscan amphora production at Vulci: Evidence from petrographic and compositional analysis

This study investigates the production of Etruscan transport amphorae from Vulci (central Italy) through an integrated programme of ceramic petrography and bulk compositional analysis (ICP-MS). A total of 48 amphora samples, collected during two sampling campaigns (2021 and 2023)...

Integrated metagenomic and phosphorus fractionation analyses elucidate the mechanism driving soil phosphorus immobilization under erythromycin stress

Erythromycin (EM) is widely detected in agroecosystems, yet its mechanistic impact on microbially driven soil phosphorus (P) cycling remains limited. Here, we integrated Hedley P fractionation with metagenomic sequencing in soil microcosms exposed to EM (0, 10, and 50 mg/kg) to t...

Mechanistic roles of the NLRP3–caspase-1 signaling axis in atherosclerosis: pyroptosis, interaction networks, and therapeutic targets

Atherosclerosis (AS) is a chronic inflammatory condition marked by lipid and immune cell accumulation in arteries, leading to plaque formation and vascular dysfunction. The nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammaso...

MemTrax as a scalable digital triage tool for mild cognitive impairment screening: primary validation in Alzheimer’s disease and exploratory analysis in Parkinson’s disease

Alzheimer’s disease (AD) and Parkinson’s disease (PD) pose escalating global health challenges, with early detection of mild cognitive impairment (MCI) being critical for timely intervention. The 2023 Delphi consensus highlights the need for scalable tools suitable for primary ca...

Predictive validity of the Addenbrooke’s cognitive Examination III for on-road driving outcomes in a clinical fitness-to-drive population: a prospective cohort study

Background Evidence-based fitness-to-drive assessment must balance public safety and fairness. Cognitive screens are commonly used, but must be accurate in high-stakes contexts. The predictive utility of the Addenbrooke’s Cognitive Examination III (ACE-III) for driving outcomes r...

Win ratio analysis of surgical approaches for lung cancer: a nationwide observational study using the French national hospital discharge database

Minimally invasive surgical approaches have gained widespread adoption, yet comparative evidence integrating multiple hierarchical endpoints remains limited. Our objective was to compare the surgical approaches for lung cancer resection (thoracotomy, VATS, robot-assisted surgery)...

Risk of Dementia after initiation of GLP-1 RA versus long-acting insulin in patients with type 2 Diabetes mellitus

Background Recent studies suggest a decreased risk of dementia in patients treated with glucagon-like peptide-1 receptor agonist (GLP-1 RA). In this study, we compare the risk of dementia associated with GLP-1 RA versus long-acting insulin in adults aged over 50 years with type 2...

Prevotella stercorea links gut microbiome ecology to respiratory infection protection through host-context-dependent, richness-independent associations

Using a longitudinal cohort of 633 Gambian children (IHAT-GUT, NCT02941081), we investigated two ecologically distinct pathways potentially linking Prevotella stercorea abundance to infection risk: a community-mediated pathway operating through overall gut microbiome richness, an...

Hierarchical adversarial learning with culture-aware attention and LLM knowledge distillation for cross-cultural sentiment analysis

Cultural frame bias significantly degrades sentiment analysis performance across different media systems, often causing accuracy drops of up to 30% during cross-cultural transfer. Existing pre-trained models struggle to disentangle culture-specific editorial framing from true sen...

Design method for vibration fatigue suppression of railway freight car body structures and its full-scale vehicle verification

This study investigates the frequent early cracking of sidewall welds in a specific export railway hopper car under mechanized vibration unloading conditions, aiming to reveal the fracture mechanism and propose an effective suppression method. The investigation revealed that the...

Novel CTLA4 Haploinsufficiency with Pure Red Cell Aplasia as the Core Manifestation: Insights from a Sibling Pair with Divergent Tumorigenic Outcomes

Cytotoxic T‑lymphocyte antigen‑4 (CTLA4) is a key immune checkpoint molecule, and its haploinsufficiency can lead to a highly heterogeneous immune dysregulation syndrome; however, its association with pure red cell aplasia (PRCA) remains to be systematically characterized. Here w...

Surgical approaches for screw fixation of calcaneal fractures: a systematic review

To systematically review and summarize the evidence related to different screw configurations in the internal fixation treatment of calcaneal fractures. This systematic review (PROSPERO registration CRD420261389986) employed a comprehensive literature search of PubMed/MEDLINE, Em...

Treatment outcomes and safety of telitacicept in reducing proteinuria and hematuria for refractory childhood IgA vasculitis nephritis

IgA vasculitis nephritis (IgAVN) is one of the most prevalent glomerulopathies in children. However, therapeutic options remain constrained. This study endeavors to elucidate the efficacy and safety of telitacicept in IgAVN children. This study encompassed 19 biopsy-confirmed IgA...

Non-isothermal reduction of TeO2 by hydrogen: Integrated distributed-activation-energy-model (DAEM)-shrinking-core-model (SCM) kinetic modeling and enthalpy-entropy compensation analysis

The non-isothermal reduction of TeO 2 (tellurium dioxide) by hydrogen (H 2 ) was investigated using thermal analysis (TG/DTG) techniques at multiple heating rates (1.0, 4.8, 9.6, and 18.8 K/min). Reaction kinetics were evaluated through an integrated Distributed Activation Energy...

Building global range maps for terrestrial insects with species range kernels and modeled aggregations of georeferenced records

Range maps for most terrestrial invertebrates generally are not accessible as spatial data. My objective was to build global range maps for 11,844 terrestrial insect species, specifically pollinator species with at least 400 georeferenced records each, by applying species range k...

Public evidence under Article 50: a baseline snapshot of twelve consumer AI products against the EU AI Act transparency clauses

AI disclosure: parts of this text were artificially generated with AI assistance and reviewed by the author. The model and the conflict it creates are named in the note at the end of the snapshot and in the README. Article 50 of the EU AI Act began to apply on 2 August 2026. This...

A 112-Vertex Counterexample to the Petersen Coloring Conjecture

This record reports an explicit simple connected bridgeless cubic graph on 112 vertices and 168 edges with no Petersen coloring, and equivalently no normal 5-edge-coloring. The main graph is identified by the normalized sorted-edge-list SHA-256 digest dc16cc18600cf77c8661b7baf89c...

Assembly Gap Enrichment in Human Chromosomes Detected via Windowed Thermodynamic Approximation (WTA)

Assembly Gap Enrichment in Human Chromosomes Detected via Windowed Thermodynamic Approximation (WTA) Abstract Background. Assembly gaps — runs of undetermined nucleotides ('N') in genomic reference assemblies — are conventionally interpreted as technical sequencing artifacts. We...