Research works

AASLD EXPO: Liver biopsy

Background: Liver biopsy is a foundational tool in hepatology, providing direct histologic assessment of hepatic parenchyma. Although noninvasive approaches have substantially reduced the need for biopsy in practice, it continues to play a critical role in diagnosis, staging, and...

The GRAVITY score (grading severity and frequency in hemorrhoidal disease): development and initial evaluation of a composite patient-reported outcome measure

Abstract Background Hemorrhoidal disease (HD) is characterized by heterogeneous symptoms including bleeding, prolapse, pain, itching, and soiling. Currently available patient-reported outcome measures evaluate complementary but distinct symptom dimensions. The aim of this study w...

A Cu(II) complex-driven supramolecular array: synthesis, crystal structure, Hirshfeld surface analysis and application in dyes adsorption

Using benzilic acid (BA) and 1-Methylimidazole (1-Me-Imi) ligands, a new Cu(II) complex is prepared, formulated as, [Cu(BA)2(1-Me-Imi)2(H2O)] (1). In the structure, the Cu(II) metal ion adopted a distorted square-pyramidal geometry, completed by two BA ligands, two 1-Me-Imi ligan...

Exploring provider preferences for HIV treatment support packages integrating long-acting injectable antiretroviral therapy in New York Ryan White Part A medical case management programs

Background: Understanding the preferences of core HIV medical case management (MCM) program staff for long-acting injectable antiretroviral therapy (LAI ART)-related support services could help integrate those services into MCM programs, thus facilitating uptake of LAI ART and in...

Three decades of sexual and reproductive health literacy and information behaviour research on adolescent and young adult males: a scoping review

The transition to adulthood for adolescent and young adult males, those aged 17 to 24, is often characterized by heightened sexual and reproductive health (SRH) risks. These risks are frequently attributed to rigid masculinity norms, insufficiently targeted health interventions,...

N-terminal proVGF modifications related to Amyotrophic Lateral Sclerosis

Objective: Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by motor dysfunction, for which effective therapies and early diagnostic biomarkers remain limited. This study comprehensively investigated ALS-associated alterations in the N...

Stereoselective 1,2-Metalate Rearrangement of α-Chloroalkylboronic Esters with gem -Diborylalkanes

Abstract Highly diastereoselective 1,2-metalate rearrangements of α-haloalkylboronic esters that simultaneously construct contiguous stereogenic centers remain limited. Herein, we report a highly diastereoselective and stereospecific 1,2-metalate rearrangement of enantioenriched...

A Novel Framework for Joint Segmentation-Registration-Bias Correction in Low-Contrast Images

Abstract. Low-contrast medical images pose significant challenges for segmentation due to weak intensity gradients and ambiguous boundaries (e.g., in prostate or brain tumor regions). Traditional methods, such as thresholding or edge detection, often fail to simultaneously addres...

Failure-guided optimisation of castellated steel beams with circular and hexagonal openings

This study presents an analytical–numerical framework for the failure-guided assessment and design exploration of castellated beams with circular and hexagonal openings across six beam spans (300–800 cm). The framework uses five metaheuristic optimisation algorithms, applied indi...

Novel ultra-compact 868 MHz/5GHz lowpass–bandpass diplexer for IoT

In this paper, we present a novel lowpass–bandpass diplexer designed to operate at frequencies of 868 MHz and 5 GHz. This diplexer is designed to overcome the limitations identified in previous studies. Notably, it achieves a maximum group delay of – 0.77 ns in the second passban...

The Fluid Mechanics of Stroke

Stroke remains a leading global cause of death and disability, originating from disruption of blood supply to brain tissue either from blockage or rupture of a blood vessel in the brain. Understandably, fluid mechanics plays a critical role in stroke mechanisms, disease manifesta...

A Study on Pyrolysis Characteristics and Product Release Mechanisms of Oil Shale

Abstract To investigate the effects of reaction atmosphere on the oxidative thermal conversion and product-evolution characteristics of oil shale, Maoming oil shale and its extracted kerogen were examined by thermogravimetric analysis (TG) and simultaneous thermal analysis couple...

Systematic analysis of peer to peer network attacks in blockchain technology examining strategies real world cases and cross layer vulnerabilities

Abstract The peer-to-peer (P2P) network layer, the foundation of the system, tends to be underplayed in blockchain security conversations about headline-grabbing applications and consensus rules. This work digs deep into the P2P layer and discovers it to be a critical front for t...

Communicating EU External Action: What Role for Strategic Narratives in the Commission's Promotion of the Global Gateway?

Abstract When the European Union promotes its external policies, it usually goes largely unnoticed. This was different for the EU's flagship initiative for external investments, the Global Gateway, which quickly created a public discussion amongst European pundits about what it m...

Clinical and imaging predictors of cerebrovascular stroke in patients with acute isolated dizziness/vertigo: a retrospective cohort study

Abstract Background Acute isolated dizziness/vertigo represents a significant diagnostic challenge, as it can be the sole manifestation of posterior circulation stroke. This study aimed to identify clinical and imaging features associated with stroke in a specific high-risk subgr...

Defects in medium-and high-entropy materials: a review

Abstract Medium- and high-entropy materials (M/HEMs) contain at least three principal elements with equal or near-equal fractions, thus representing the unexplored middle parts of phase diagrams. These substances include both metallic and ceramic materials. M/HEMs exhibit outstan...

Adaptive Damping Control for Stability Enhancement of Grid-Following Converters Based on q-Axis Voltage Magnitude Feedback

Grid-following converters are prone to transient synchronization instability during grid faults, which may lead to the disconnection of renewable energy devices and threaten the security and stability of power systems. To address this issue, this paper first establishes a second-...

A Bistable UV-Sensitive Opsin from a Reef Building Coral Showing a Switchable and Tunable Regulation of Gs-Signaling by Different Wavelengths of Light

Abstract Cnidarians possess a large number of opsins in their genomes for their various photoreceptive functions. In particular, they uniquely possess Gs-coupled opsins that induce intracellular cAMP accumulation in a light-dependent manner. These Gs-coupled opsins, cnidopsins, a...

Monopulse electrodeposited nanoflower-like Co-Mo-P/Cu catalyst for efficient hydrogen production from hydrolysis of sodium borohydride: Synergistic mechanism and electrochemical reactivation

High-performance catalysts for hydrogen generation from sodium borohydride (NaBH 4 ) hydrolysis are pivotal for portable energy applications. In this work, a hierarchical Co-Mo-P/Cu catalyst with spherical nanoflower structure was synthesized via a facile one-step monopulse flow...

Characteristics and associated risk factors of opportunistic infection in children with systemic lupus erythematosus in under-resourced areas

Objective Infection is a major factor in morbidity and mortality among pediatric systemic lupus erythematosus (SLE) patients, particularly opportunistic infections (OI), which can result in severe clinical outcomes. There is a scarcity of data regarding OI in children with SLE in...