Health & Medicinearticle2026-10-06

FDG-PET/CT Evaluation of Pulmonary Artery Sarcoma Masquerading as Pulmonary Embolism

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Abstract

A 20-year-old woman underwent evaluation for cardiopulmonary symptoms initially attributed to pulmonary embolism of uncertain chronicity. Positron emission tomography/computed tomography (PET/CT) revealed an intensely fluorodeoxyglucose (FDG)-avid mass within the right pulmonary artery, suggestive of a malignant process. Surgical resection and histopathologic examination confirmed high-grade spindle cell sarcoma with developing pulmonary infarcts. This case highlights the role of PET/CT in distinguishing a malignant intravascular tumour from thrombus in atypical presentations.

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View paper (DOI)Open access versionOpenAlexIndian Journal of Nuclear MedicinePublished 2026-10-06

Authors: Chris Hsu, Rashid Syed, Gopal Kumar Yadav, David Ricardo Cardoza-Ochoa, Olushola Ogunleye, Esosa Odigie‐Okon, Peeyush Bhargava

Institutions: The University of Texas Medical Branch at Galveston, Texas A&M University at Galveston