The University of Texas Medical Branch at Galveston

Disease-specific tau polymorphs are associated with unique protein networks across proteinopathies

Abstract Tau protein aggregates adopt distinct conformations across tauopathies, yet the protein interactions engaged by disease-specific polymorphs remain poorly characterized. Here, we demonstrate that conformationally distinct tau polymorphs associate with disease-specific int...

Imaging of ectopic gastric mucosa in Meckel’s diverticulum: A case report and literature review

Meckel’s diverticulum (MD) is usually asymptomatic, with the most common presentation being painless gastrointestinal bleeding in children under the age of 2 years. We report a case of a 10-year-old male who presented with painless hematochezia and melena, accompanied by several...

Continuing Trend of Increased Operative Treatment of Clavicle Fractures in Pediatric Patients in the United States Despite a Lack of Supporting Evidence in the Literature

Introduction: Pediatric clavicle fractures are among the most common fractures in this age group. Current research supports the efficacy of nonoperative treatment for these injuries in pediatric patients. Our study seeks to examine the current trends in the management of these fr...

suPAR Identifies Treatment-Resistant Inflammatory Risk Beyond hs-CRP in Type 2 Diabetes With Coronary Artery Disease: An Ancillary Analysis of BARI 2D

OBJECTIVE To determine whether soluble urokinase plasminogen activator receptor (suPAR) is modified by randomized diabetes and revascularization strategies in patients with type 2 diabetes and coronary artery disease and whether combined suPAR and hs-CRP classification refines re...

Evaluating the Feasibility and Preliminary Effectiveness of a Tailored Diabetes Education Program for Rural Residents

Introduction: Diabetes is a top ten Rural Healthy People 2030 priority for health improvement among rural Americans. Socioeconomic, environmental, geographic and political barriers contribute to the type 2 diabetes (T2D) prevalence and its disparate impact in rural communities. H...

Larval crowding in Culex pipiens generates cumulative cascading effects under changing environmental conditions

Density-dependent population regulation is a fundamental driver in the population dynamics of living systems, ensuring a balanced and sustainable maintenance in nature. It has been suggested that the adverse developmental and morphological effect of high larval density in contain...

HIF1A-dependent induction of alveolar miR-147b dampens SARS-CoV-2-associated ARDS via direct targeting of viral RNA

BACKGROUND: Acute respiratory distress syndrome (ARDS) causes significant morbidity and mortality during viral pneumonia, including SARS-CoV-2 infections. Nevertheless, most patients with SARS-CoV-2 infections recover seamlessly without developing ARDS, suggesting the existence o...