Stereoselective Gateway to Decorated Chloro-1,3-butadienes from Allenols via Deoxygenative 1,2-Bond Migration

Abstract

Abstract We disclose an efficient strategy for the selective synthesis of E-2-chloro-1,3-butadienes from allenols. This modular approach offers an extensive substrate scope with moderate-to-good yields and operational simplicity. Additionally, they offer a versatile platform for synthetic diversification and are highly scalable.