Indian Institute of Technology Ropar

Thiol Deodorization Using Cu(II)/Ag(I)-Metal–Organic Gel-Based Photocatalyst in a Coiled Flow Inverter: Experimental and CFD Insights

Abstract The combination of photochemistry and flow chemistry enables substantial improvement in reaction efficiency. By adopting this approach, the study focuses on the treatment of malodorous volatile thiols that pose serious environmental and health concerns due to their low o...

Beyond Antibodies: Glypican‐3‐Targeting Peptides for Precision Hepatocellular Carcinoma Theranostics

ABSTRACT Glypican‐3 (GPC‐3) is a cell‐surface glycoprotein, highly expressed in hepatocellular carcinoma (HCC) but largely absent in normal adult liver tissues, making it a clinically compelling biomarker and therapeutic target. Although monoclonal antibodies and antibody‐drug co...

Physics-guided Gaussian process framework for data-efficient optimization of APCVD growth of 2D semiconductor WS2

Layer-controlled growth of two-dimensional transition-metal dichalcogenides (2D TMDs), such as Tungsten Disulfide (WS 2 ), remains challenging due to the nonlinear interplay among multiple parameters associated with the atmospheric pressure chemical vapor deposition (APCVD) growt...

Engineering [7]helicene via peripheral boron-nitrogen Lewis pair fusion: from synthesis to cellular imaging.

-helical enantiomers, which adopt an ordered heterochiral packing arrangement in the solid state. Furthermore, the helical boron-nitrogen adduct was investigated in cell imaging studies, where it exhibits enhanced intracellular photostability, lower cytotoxicity, and effective st...

Leveraging Iodomethylboronic Ester Reactivity to Access Late-Stage Dehydroalanine and Dehydrovaline onto Peptides in Water

Abstract We report a mild, chemoselective late-stage conversion of cysteine and penicillamine residues into dehydroalanine (Dha) and dehydrovaline (ΔVal), respectively, in peptides via rapid bis-alkylation with the commercially available iodomethylboronic acid pinacol ester (IMBp...

Stereoselective Gateway to Decorated Chloro-1,3-butadienes from Allenols via Deoxygenative 1,2-Bond Migration

Abstract We disclose an efficient strategy for the selective synthesis of E-2-chloro-1,3-butadienes from allenols. This modular approach offers an extensive substrate scope with moderate-to-good yields and operational simplicity. Additionally, they offer a versatile platform for...

Note on higher spins and holographic symmetry algebra

A bstract In this paper we discuss a higher-spin extension of the holographic symmetry algebra for graviton and gluon. Our primary observation is that in the presence of higher-spin particles the soft symmetry algebra has a subalgebra isomorphic to w ∞ which is generated by the c...

Synthetic Approaches to Conjugated Polycyclic Hydrocarbons Featuring the Antiaromatic Indeno[2,1-c]fluorene Scaffold

Fully conjugated indeno[2,1-c]fluorene, a fragment of fullerene-C60, is a structural isomer of the 20π indenofluorene family, which is viewed as the antiaromatic analogue of the aromatic acene(s). Compared to the linear indeno[1,2-b]fluorene isomer featuring a para-quinoidal s-in...

Pd-Catalyzed Chemodivergent Monodefluorinative Cascade Cyclizations of gem -Difluorovinyl-Conjugated Alkynylanilines to Fluorinated Benzocarbazoles and Indoloisoquinolines

Abstract An efficient one-pot Pd-catalyzed reaction medium-directed chemodivergent protocol has been developed that enables the controlled assembly of meta-fluorinated benzocarbazoles, fluoroindoloisoquinolines, and their halogenated analogues from easily synthesizable gem-difluo...

Physics-informed adversarial networks for stochastic second-order mean-field games of autonomous traffic

Abstract Inspired by the highly complex and nonlinear traffic flow phenomenon, we propose a second-order continuum model for autonomous vehicles (AVs) by considering them as rational and utility-optimizing agents. Further, by accounting for stochastic fluctuations in driving dyna...

Emerging Two‐Dimensional vdW Materials and Their Heterostructures for Memristive Devices: Advances, Challenges, and Perspectives

ABSTRACT The continuous scaling of conventional CMOS technology has posed critical challenges for modern electronic systems, including high power consumption and limited memory density. The major challenge in current computing systems is the von Neumann bottleneck, which arises f...

Adaptive behavioural strategies promote species persistence in niche-constrained ecological communities

Abstract Species persistence in ecosystems results from the interplay between ecological interactions and behavioural strategies. Classical niche theory explains how resource overlap determines the strength of interactions, while evolutionary game theory (EGT) describes how coope...

Random Silicon Micromirrors for Enhanced Emission Rate and Spin Readout Contrast of NV Centers

ABSTRACT The nitrogen‐vacancy (NV) center in diamond exhibits spin‐dependent optical response at room temperature, making it a driving force in quantum computing, memory, and sensing. In practice, shot‐noise magnetic sensitivity is often constrained by very low collection efficie...